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Interviewees x

1 Alphabetical list of people interviewed by the Polish Research Institute in Lund The witness testimonies are numbered 1-514. Sixteen testimonies were considered to contain particularly sensitive information by the working group and were classified until 2004; those are numbered T1-T16. Some testimonies were never completed and given a number. Nine numbered testimonies have been missing since the

https://www.ub.lu.se/sites/ub.lu.se/files/interviewees_x.pdf - 2026-05-20

Recognizing Microscopic Structures: Dense Semantic Segmentation of Multiple Histopathological Classes using Fully Convolutional Neural Networks

In order to alleviate the financial burden on the healthcare sector as well as relax its employees’ workload, there is a need to introduce novel tools that automate some of the tasks that today are performed manually. Especially pathology poses a problem with few pathologists, demanding manual labour and unnecessary work on benign tissue. As a response, the DOGS project aims to develop a tool to a

Effects of oestradiol and raloxifene on the induction and effector phases of experimental postmenopausal arthritis and secondary osteoporosis.

Oestradiol and the selective oestrogen receptor modulator (SERM) raloxifene have been shown to ameliorate collagen-induced arthritis (CIA) in rats and in mice. One aim was to investigate if raloxifene exerts its anti-arthritic and anti-osteoporotic effects during the induction or effector phase of arthritis. A second aim was to analyse if raloxifene activates the oestrogen response element (ERE) t

Serum from patients with systemic vasculitis induces alternatively activated macrophage M2c polarization.

Anti-neutrophil cytoplasmic antibody associated vasculitides (AAV) are conditions defined by an autoimmune small vessel inflammation. Dying neutrophils are found around the inflamed vessels and the balance between infiltrating neutrophils and macrophages is important to prevent autoimmunity. Here we investigate how sera from AAV patients may regulate macrophage polarization and function. Macrophag

Baseline IGF-I Levels Determine Insulin Secretion and Insulin Sensitivity during the First Year on Growth Hormone Therapy in Children Born Small for Gestational Age. Results from a North European Multicentre Study (NESGAS)

Objective: Developmental programming alters growth and metabolic outcome in children born small for gestational age (SGA). We explored insulin and glucose metabolism in SGA children treated with a fixed GH dose over 1 year. Methods: In the North European Small for Gestational Age Study (NESGAS), 110 short SGA children received GH at 67 mu g/kg/day for 1 year. Insulin secretion was assessed by acut

Randomized Controlled Study of the Safety and Immunogenicity of Pneumococcal Vaccine Formulations Containing PhtD and Detoxified Pneumolysin with Alum or Adjuvant System AS02(V) in Elderly Adults

Six vaccine formulations containing AS02(V) or alum (aluminum phosphate [AlPO4]) adjuvant with pneumococcal proteins, pneumococcal histidine triad D (PhtD), and/or detoxified pneumolysin (dPly), either as a polysaccharide carrier in an 8-valent pneumococcal conjugate vaccine (8PCV) or as free (unconjugated) proteins, were evaluated in adults -65 to 85 years of age. In this phase I observer-blind s

Projected Rotational Velocities of 136 Early B-type Stars in the Outer Galactic Disk

We have determined projected rotational velocities, v sin i, from Magellan/MIKE echelle spectra for a sample of 136 early B-type stars having large Galactocentric distances. The target selection was done independently of their possible membership in clusters, associations or field stars. We subsequently examined the literature and assigned each star as Field, Association, or Cluster. Our v sin i r

An epigenetic mechanism for high, synergistic expression of indoleamine 2,3-dioxygenase 1 (IDO1) by combined treatment with zebularine and IFN-γ: Potential therapeutic use in autoimmune diseases.

IDO1 can be induced by interferon gamma (IFN-γ) in multiple cell types. We have earlier described that the DNA methyltransferase inhibitor zebularine also induces IDO1 in several rat cell clones. We now describe a synergistic induction of IDO1 expression by IFN-γ and zebularine. To elucidate the mechanism of the IDO1 induction we have studied the methylation status in the promoter region of the ID

Colour holography in optics courses at Lund Institute of Technology

Several physics courses are given at Lund Institute of Technology. In the basic courses on ray and wave optics, holography has played an important role both in stimulating the students to curiously investigate the optical world and as an important visualisation of some obvious and interesting parts of the courses. To meet the need for basic laboratory experience, a holographic laboratory has been

The Dead Sea Future Elevation Based on Water and Salt Mass Balances

Water and salt mass balances for the Dead Sea were modeled. Precipitation, evaporation, river discharges, ground water flows, input/output from potash companies and salt production, and brine discharge were included in the models. The mixing time in the Dead Sea was modeled using a single-layer (well-mixed) a two-layer (stratified) system. Using the single-layer approach the water level was predi

Successive interference cancellation in multistream faster-than-Nyquist signaling

In earlier work we have extended Mazo's concept of faster-than-Nyquist signaling to pulse trains that modulate adjacent subcarriers, a method we called two dimensional Mazo signaling. The signal processing is similar to orthogonal frequency division multiplex (OFDM) transmission. Despite pulses that are faster than the Nyquist limit and subcarriers that significantly overlap, the transmission achi

Three-dimensional laser induced fluorescence of fuel distributions in an HCCI engine

Three-dimensional imaging of fuel tracer planar laser-induced fluorescence in a homogeneous charge compression ignition (HCCI) engine is presented. A high-speed multiple Nd:YAG laser and detection system, in combination, with a scanning mirror, are used to collect eight images, with an equidistant separation of 0.5 mm. Three-dimensional isoconcentration surfaces calculated from the data are visual

Multiple Loci in the HLA Complex Are Associated with Addison's Disease.

Context: A strong association between autoimmune Addison's disease (AAD) and major histocompatibility complex class II-encoded HLA-DRB1-DQA1-DQB1 haplotypes is well known. Recent evidence from other autoimmune diseases has suggested that class I-encoded HLA-A and HLA-B gene variants confer HLA-DRB1-DQA1-DQB1-independent effects on disease. Objective: We aimed to explore AAD predisposing effects of

FPGA implementation of controller-datapath pair in custom image processor design

In order to reduce the effort of the controller design in the customized image convolution processor, a controller synthesis tool is developed based on [9] to support the design flow from a system or algorithm specification to RTL level VHDL. Architecture extensions to basic FSMs structures are implemented with the purpose of optimizing controller design for area and power consumption. Together wi

Generation of a conditionally null allele of the laminin alpha 1 gene

Laminins are heterotrimeric glycoproteins of the basement membranes. Laminin 1 (alpha 1, beta 1, gamma 1) is the major laminin expressed during early mouse embryogenesis. To gain access, to the physiological function of laminin alpha 1 chain, we developed a conditionally null allele of its encoding gene (Lama1) using the cre/loxP system. Floxed-allele-carrying mice (Lama1(flox/flox)) display no ov

Insulin and free oestradiol are independent risk factors for benign prostatic hyperplasia

The aetiology of benign prostatic hyperplasia (BPH) remains unclear. The objective of the present study was to test the insulin, oestradiol and metabolic syndrome hypotheses as promoters of BPH. The design was a risk factor analysis of BPH in which the total prostate gland volume was related to endocrine and anthropometric factors. The participants studied were 184 representative men, aged 72-76 y

Interstitial photodynamic therapy for primary prostate cancer incorporating realtime treatment dosimetry

Photodynamic therapy (PDT) for the treatment of prostate cancer has been demonstrated to be a safe treatment option capable of inducing tissue necrosis and decrease in prostate specific antigen (PSA). Research groups report on large variations in treatment response, possibly due to biological variations in tissue composition and shortterm response to the therapeutic irradiation. Within our group,

Effects of harvest time and storage on dietary fibre components in various cultivars of white cabbage (Brassica oleracea var capitata)

The effect of harvest time and storage on dietary fibre content and composition was investigated in six cultivars of white cabbage (Brassica oleracea var capitata). Three cultivars were of early maturity type (SW Nordpol, Rolly and Balbro) and three of late maturity type (Predikant, Hanna and Lion). The average total dietary fibre (TDF) content was 241 g kg(-1) dry matter (DM) (CV = 13), of which