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Understanding the shape and diversity of dwarf galaxy rotation curves in ΛCDM

The shape and diversity of dwarf galaxy rotation curves is at apparent odds with dark matter halos in a Λ Cold Dark Matter (ΛCDM) cosmology. We use mock data from isolated dwarf galaxy simulations to show that this owes to three main effects. Firstly, stellar feedback heats dark matter, leading to a `coreNFW' dark matter density profile with a slowly rising rotation curve. Secondly, if close to a

Characterizing gravitational instability in turbulent multicomponent galactic discs

Gravitational instabilities play an important role in galaxy evolution and in shaping the interstellar medium (ISM). The ISM is observed to be highly turbulent, meaning that observables like the gas surface density and velocity dispersion depend on the size of the region over which they are measured. In this work, we investigate, using simulations of Milky Way-like disc galaxies with a resolution

Larson's scaling laws, and the gravitational instability of clumpy discs at high redshift

Gravitational instabilities play a primary role in shaping the clumpy structure and powering the star formation activity of gas-rich high-redshift galaxies. Here, we analyse the stability of such systems, focusing on the size and mass ranges of unstable regions in the disc. Our analysis takes into account the mass-size and linewidth-size scaling relations observed in molecular gas, originally disc

A Toomre-like stability criterion for the clumpy and turbulent interstellar medium

We explore the gravitational instability of clumpy and turbulent gas discs, taking into account the Larson-type scaling laws observed in giant molecular clouds (GMCs) and H i, as well as more general scaling relations. This degree of freedom is of special interest in view of the coming high-z interstellar medium surveys and is thus potentially important for understanding the dynamical effects of t

Mechanistic Toxicology : Molecular interactions and underlying mechanisms of dendritic cell activation in skin sensitization

Allergic skin diseases caused by low molecular weight chemical compounds are a major health concern among the general population, especially in certain occupational groups. To limit exposure to such compounds, it is important that thorough risk assessments are performed before products reach the consumer market. Traditionally, such risk assessments have been based on animal tests, but due to sever

Gender differences in subtypes of depression by first incidence and age of onset : a follow-up of the Lundby population

The Lundby Study is a prospective mental health survey in a community population (N = 3563), in which data were collected in 4 waves of field-work between 1947 and 1997. We investigated gender differences during the follow-up in overall first incidence rates, ages of onset, and incidence by age of onset patterns, in different subtypes of depression. The overall incidence rate in females was higher

Brief Admission Skåne (BAS), an intervention for indivi- duals with symptoms of borderline personality disorder, recurrent self-harm, at high risk for suicide. : Brief admission Skåne: Evaluation of fidelity to the method and individual-therapist experiences

Objectives: To measure treatment fidelity and to evaluate patient and clinician experiences with Brief Admission Skåne (BAS) over the pilot phase and first five months of the intervention phase of a randomized controlled trial (RCT) testing BAS. The purpose of the RCT is to determine whether BAS can reduce the frequency of acute psychiatric admissions for individuals with borderline personality di

Toy Consumption as Political : Challenges for Making Dreams Come True

This chapter looks at political consumerism in the toy sector, offering a brief history of consumer concerns and distinguishing among four strands of political consumerist research in this sector. A primary factor facilitating political consumerism of toys is that toy companies are extremely concerned about their reputation. Manufacturers cannot assume that parents and other carers do their usual

Developing legislation to prevent environmental damage from products : A herculean but necessary task

Why a Book about Product-Oriented Environmental Law? While laws relating to the environment have been around for centuries, it could be argued that modern environmental lawmaking started in the 1960s, when many nations began adopting acts specifically targeting the environment. The evolution of environmental law since then has followed several paths, from mainly local regulations to national, Euro

Present and future challenges for Europe’s environmental product policy

Concerns about the environmental effects of the ‘throwaway society’ are increasingly influencing policy-making and regulatory action in the EU. The Seventh Environment Action Programme, which aims to guide European environmental policy, sets out a long-term vision for the EU that requires a major shift in the way economic activities are conducted: In 2050, we live well, within the planet’s ecologi

Energy efficiency regulations, market and behavioural failures and standardization

Introduction: A large number of policy instruments have been developed to induce energy efficiency and mitigate climate change. Traditional policy evaluations have assessed the performance of individual policy instruments, applying criteria such as target effectiveness, cost-effectiveness, legitimacy and distributional effects. More recently there has been a shift of interest in how policy instrum

Managing a Century of Debt

This paper provides a consistent series for the Irish national debt since the foundation of the state. It also provides a continuous series for bond yields over the same period. The paper examines the factors behind the fluctuations in the debt burden over almost a century. The management of the debt burden by the Irish authorities has evolved over time, seeking to minimise both the burden on the

Secure generalized deduplication via multi-key revealing encryption

Cloud Storage Providers (CSPs) offer solutions to relieve users from locally storing vast amounts of data, including personal and sensitive ones. While users may desire to retain some privacy on the data they outsource, CSPs are interested in reducing the total storage space by employing compression techniques such as deduplication. We propose a new cryptographic primitive that simultaneously real

S100A9 in inflammation

S100A9 is a small (13 kD) cytosolic calcium-binding protein. The protein is mainly expressed in neutrophils and monocytes in human but can also be expressed in other cell types under inflammatory conditions. S100A9 is normally co-expressed with S100A8 and forms S100A8/S100A9 heterodimers. Previous publications had suggested that S100A9 could be expressed without S100A8 in certain conditions. Vario