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Transcription factor AP-4 is a ligand for immunoglobulin-κ promoter E-box elements
Immunoglobulin (Ig)-κ promoters from humans and mice share conserved sequences. The octamer element is common to all Ig promoters and pivotal for their function. However, other conserved sequence motifs, that differ between lg variable gene families, are required for normal promoter function. These conserved motifs do not stimulate transcription in the absence of an octamer. One example is an E-bo
Implementation at Multiple Levels
Temporal quality of post-compressed pulses at large compression factors
Post-compression of ultra-short laser pulses via self-phase modulation is routinely employed for the generation of laser pulses with optical bandwidths reaching far beyond the laser gain limitations. Although high compression factors can be routinely achieved, the compressed pulses typically suffer from temporal quality degradation. We numerically and experimentally analyze the deterioration of di
Disability, Justice and Freedom as Non-Domination
Disability scholars have recently proposed that republican theory is relevant to think about justice in relation to disability. Following in their footsteps, this article submits that the republican conception of freedom as non-domination provides a fresh angle to legitimise disability rights in terms of justice and prevent their interpretation as charity or privileges. This proposition takes its
Danish stød as a cue to upcoming suffixes : An ERP and response time study
Multilevel Climate Governance in Brazil and Indonesia : Domestic Pioneership and Leadership in the Global South
Focusing on forest policy and urban climate politics in Brazil and Indonesia, the primary objective of this chapter is to identify domestic pioneers and leaders who, compared to other sectors, governmental levels or jurisdictions within the same nation-state, move ‘ahead of the troops’ (Liefferink and Wurzel, 2017: 2-3). The chapter focuses especially on the role of multilevel governance in bringi
Degrowth
This chapter is devoted to introducing degrowth to anyone interested in environmental politics and making connections between the two areas. It articulates critiques of growth, alternatives associated with degrowth and the politics of pursuing them. It is argued that economic growth, with GDP being its key indicator, comes with environmental degradation and is rooted in injustices. Degrowth schola
Vorsprung durch Technik: The Future of Work, Digital Technology, and the Platform Economy
1H detection and dynamic nuclear polarization–enhanced NMR of Aβ1-42 fibrils
Several publications describing high-resolution structures of amyloid-β (Aβ) and other fibrils have demonstrated that magic-angle spinning (MAS) NMR spectroscopy is an ideal tool for studying amyloids at atomic resolution. Nonetheless, MAS NMR suffers from low sensitivity, requiring relatively large amounts of samples and extensive signal acquisition periods, which in turn limits the questions tha
Wind induced circulation in a lake
Finland’s election: what happened to Sanna Marin and what to expect next
Nobody's Perfect : On Trust in Social Robot Failures
With robots increasingly succeeding in exhibiting more human-like behaviours, humans may be more likely to ‘forgive’ their errors and continue to trust them as a result of ascribing higher, more human-like intelligence to them. If an integral aspect of successful HRI is to accurately communicate the competence of a robot, it can be argued that the technical success of the robot in exhibiting human
The young HD 73583 (TOI-560) planetary system : two 10-M⊕ mini-Neptunes transiting a 500-Myr-old, bright, and active K dwarf
We present the discovery and characterization of two transiting planets observed by TESS in the light curves of the young and bright (V = 9.67) star HD73583 (TOI-560). We perform an intensive spectroscopic and photometric space- and ground-based follow-up in order to confirm and characterize the system. We found that HD73583 is a young (∼500 Myr) active star with a rotational period of 12.08 ± 0.1
Nuclear Spectators : When Globocide Turned Entertainment
Multialphabet coding with separate alphabet description
For lossless universal source coding of memoryless sequences with an a priori unknown alphabet size (multialphabet coding), the alphabet of the sequence must be described as well as the sequence itself. Usually an efficient description of the alphabet can be made only by taking into account some additional information. We show that these descriptions can be separated in such a way that the encodin
Translanguaging in English Classrooms in Sweden? : A Study of Teacher Beliefs and Practices
In English Language Teaching in Sweden, the entextualized ideology is monolingual, i.e., English Only (Hult, 2017; Lundahl, 2012). Evidence from a large-scale classroom observation study (Swedish Schools Inspectorate, 2011) and a smaller-scale classroom-interaction study (Authors 3 & 4 2016) reveals a de facto bilingual policy of both English and Swedish enacted in classrooms, however. As stud
Translanguaging Practices in English Language Teaching in Scandinavian Contexts
With the over-arching aim of contributing to the development of evidence-based teaching practices, this colloquium provides a forum for scholars doing research on language practices in the teaching of English as a foreign/second language (L2) in mainstream schools in Scandinavia. In Sweden, the English teaching profession has long been guided by monolingual, English Only, ideology, particularly at
English-Swedish Translanguaging in Multilingual Secondary English Classrooms : A Study of Students' Attitudes
A pressing issue in multilingual education is when to draw on students’ entire multilingual repertoires to enhance learning and promote equity (Cummins 2017; Kramsch 2009). Classroom research on the learning of L2 English supports multilingual/translanguaging practices (Lee & Macaro 2013; Zhang 2018), but much of this research involves students who had acquired the same L1 prior to having clas
