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Antigen-specific islet antibodies: prediction of beta cell failure and differentiation between Type 1 and Type 2 diabetes

Popular Abstract in Swedish Vid Typ 1 diabetes mellitus (insulinberoende, [ungdoms]) förlorar kroppen förmågan att tillverka insulin, det hormon som styr upptaget av socker i kroppens celler. Insulinet bildas av bukspottskörtelns hormonproducerande betaceller, och Typ 1 diabetes orsakas av att dessa celler skadas och förstörs. Denna skadeprocess anses idag i de flesta fall förmedlas av kroppens egAutoantibodies against glutamic acid decarboxylase (GADA), protein tyrosine-phosphatase-like protein (IAÐ2A), and/or pancreatic islet cells (ICA) are autoimmune markers usually present at diagnosis of Type 1 diabetes. Type 1 diabetes is therefore in general believed to be caused by an immune-mediated beta cell destruction. In children this destruction is fast, whereas in adult patients Type 1 diab

Introduction

Just like the first theories in physics viewed atoms as independent and surrounded by a void, our bodies’ microscopic constituents are often portrayed as disconnected from the body as a unified organism, and from its cultural and social contexts. In The Atomized Body the authors examine the relations between culture, society and bioscientific research and show how our bodies’ singularized atoms in

Coherence and Prominence in the Sermon on the Mount : A Systemic-Functional Approach

Language is a social phenomenon used for communication and to convey messages from one individual to another. The systemic-functional approach embraces the linguistic expression of the Sermon, the co-text, as well as its paralinguistic reference points, the context. The Sermon on the Mount is probably the most well-known passage of text in the New Testament and is a structured discourse with far-r

Outcome of case management based on the strengths model compared to standard care. A randomised controlled trial.

BACKGROUND: The outcome of less intensive case management services, such as the strengths model, is still inconclusive, which suggests a need for more controlled studies. The aim of the present study was to investigate the outcome of a strengths model of case management service (SCM) compared to standard care. METHODS: Seventy-seven clients with a mental illness and a serious impairment in functio

Omyndig, men straffmyndig - En analys av den straffrättsliga påföljdsbestämningen för unga lagöverträdare mellan 15 och 17 år

Den som är yngre än 18 år stadgas vara omyndig enligt gällande rätt, men den som är 15 år gammal kan bli föremål för straffrättsliga påföljder om den begått ett brott. Enligt gällande rätt bör dock straffrättsliga påföljder dömas ut mycket restriktivt när lagöverträdare är mellan 15 och 17 år, eftersom vårdande åtgärder angetts erhålla företräde. Enligt barnkonventionen, vilken gäller som svensk lAccording to the Swedish Parental Code (1949:381), chapter 9, section 1, a person below the age of eighteen years is considered a minor. But according to the Swedish Penal Code (1962:700), chapter 1, section 6, a person above the age of fifteen may be subject to sanctions if he or she has committed a crime. According to the Convention on the Rights of the Child, which was incorporated as Swedish l

European Commission's proposal to implement a new permanent establishment nexus based on significant digital presence - Is it compliant with the EU Law and international tax principles?

The taxation of the digital economy has become a relevant subject, as business models and value creation chains of all sectors have been transformed bringing challenges to the international tax system and parameters for the allocation of taxing rights between source and residence jurisdictions. In view of these changes, the European Commission has published two proposals for directives on the taxa

Area and power efficient trellis computational blocks in 0.13μm CMOS

Improved add-compare-select and branch metric units are presented to reduce the complexity in the implementation of trellis-based decoding architectures. These units use a complementary property of the best rate 1/2 convolutional codes to reduce both area requirements and power consumption in a silicon implementation with no loss in decoding performance. For a 0.13μm CMOS process, synthesized comp

Multi-photon lithography on thin films for efficient fabrication of 2D and 2.5D meta-atoms

Direct laser writing (DLW) has arise interest in a variety of fields due to the capabilities that we get from the realization of 2D and 3D structures with high resolution fabrication techniques. Multi-photon lithography (MPL) relies on non-linear absorption effects, making possible the fabrication of metasurfaces with feature size beyond the diffraction limit. A new approach in this direction is t

Swe consent diaprime m090118v4

Formulär för informerat samtycke M090118v4 DIAPRIME-studien Formulär för informerat samtycke M090118v4 Lunds universitet 1 INFORMATIONSBLAD DELTAGARE PROJEKTTITEL: The Diabetogenic Perturbations of the Fetal Methylome (DIAPRIME) Project (Epigenetiska förändringar hos fostret under graviditet med hög risk för nedsatt blodsockerkontroll) FINANSIÄR: Studien är delvis finansierad av den Europeiska sti

https://www.diabetesportalen.lu.se/sites/diabetesportalen.lu.se/files/swe_consent_diaprime_m090118v4.pdf - 2026-05-16