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Mutations in the NRF2-KEAP1 pathway are common in non-small cell lung cancer (NSCLC) and confer broad-spectrum therapeutic resistance, leading to poor outcomes. The cystine/glutamate antiporter, system xc-, is one of the >200 cytoprotective proteins controlled by NRF2, which can be non-invasively imaged by (S)-4-(3-18F-fluoropropyl)-l-glutamate ([18F]FSPG) positron emission tomography (PET). Throu

Electrifying road transport is seen as one of the key components in decreasing the carbon footprint of the society as a whole. Recent developments in electric drivetrain and battery technology have helped to design vehicles with ranges that make them independent of public charging infrastructure during most sub-urban and commuting trips. Once long-haul trips are planned, however, these vehicles re

In this study, we assess the impact of an image restoration pipeline, designed for digital mammography, on the detectability of microcalcifications of different sizes across varied radiation exposures. The restoration pipeline first removes the noise of the image considering a Poisson-Gaussian noise model that incorporates quantum and electronic noise. Then, it appropriately merges the noisy and d

There is currently interest in low strain HPHT diamond due to its expected application as various types of X-ray optical elements at Synchrotrons, where the X-ray intensity is becoming progressively too severe for the existing materials. The diamond crystals need to be synthesised with unprecedented lattice quality. In recent measurements at the ID19 beamline of European Synchrotron Radiation Faci

Title: The thin line between toxic leadership and transformational leadership: stories of Steve Jobs Seminar date: 1 June 2016 Course: FEKH49, Degree Project Undergraduate level, Business Administration, Undergraduate level, 15 University Credit Points (UPC) or ECTS‐cr) Authors: Amanda Bengtsson, Malin Lindskog and Sofia Jörnlid Advisor/s: Sverre Spoelstra Key words: Steve Jobs, Toxic Leadershi

Wearer trials with human subjects were included in the Subzero project in order to validate the manikins' data against practice. Physiological tests of the project were aimed to study hu-man subjects at thermal comfort or being slightly warm in cold: 0, -10, -25 and wind-chill temperature –50 ºC. Wind-chill temperature –50 was achieved by combination of 2 tempera-tures and wind velocities: -40 ºC

Popular Abstract in Swedish SVENSK SAMMANFATTNING Huvudsyftet med denna avhandling var att undersöka olika aspekter av självrapporterade sexuella övergrepp under barndom och ungdomstid i en befolkningsstudie med svenska gymnasieelever. Ett av målen var att undersöka livstidsprevalensen för olika typer av sexuella övergrepp och olika övergreppsvariabler samt relationen mellan sexuella övergrepp, köABSTRACT The purpose of this thesis was to investigate aspects of self-reported sexual abuse during childhood and adolescence in a population-based study of Swedish high school students. The aim of this thesis was first to investigate the lifetime prevalence of sexual abuse of varying severity and characteristics as well as the associations between sexual abuse, gender, socio-demographic character

CCD observations of V538 Cas have been made on nine nights during three weeks using the AAVSO Bright Star Monitor. No significant variations were found.

A data set of adaptive optics images has been analyzed in order to study the effects of angular anisoplanatism and to characterize Mauna Kea nighttime turbulence. The data set consists of a selection of Galactic center images obtained with the adaptive optics instrument Hokupa'a and the near-infrared camera QUIRC on the Gemini-North 8 m telescope. Using the Strehl ratio and the FWHM as tracers for

This paper aims to support the decision-making tasks regarding the integration of packaging development into product development. Based on the study of the interactions of the product and packaging during the whole product life cycle, a set of packaging-related factors was extracted and mapped to a general product development model, which at a strategic level can be used to define an integrated pr

Popular Abstract in Swedish Avhandlingen består av tre essäer som behandlar effekterna av inkomplett information i de finansiella marknaderna. Av dessa essäer är två teoretiska och en är huvudsakligen empirisk. Samtliga essäer undersöker effekterna av parameterosäkerhet, och de använder sig av kontinuerliga modeller. Den första essän, "The Effect of Information Quality on Optimal Portfolio ChoiceThis thesis consists of three essays on incomplete information in financial markets, two of which are theoretical, and one that is mainly of an empirical nature. All three essays concern parameter uncertainty, and they employ a continuous-time framework. The first essay, "The Effect of Information Quality on Optimal Portfolio Choice," analyzes the portfolio choices made by three types of agents,

Maternal anxiety about a child's diabetes risk in the TEDDY study: the potential role of life stress, postpartum depression, and risk perception Pediatric Diabetes 2014 doi: 10.1111/pedi.12168 All rights reserved © 2014 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd. Pediatric Diabetes Original Article Maternal anxiety about a child’s diabetes risk in the TEDDY study: the potential role

https://www.teddy.lu.se/sites/teddy.lu.se/files/06032016_679_37_roth_ped_diab_2014.pdf - 2026-05-19

This article examines how Swedish social democratic women used the enactment of universal suffrage in 1919/1921 as an argument to gain support for separate organising. The article also analyses the extent to which the Swedish National Federation of Social Democratic Women, founded in 1920, used direct (personal) and indirect (media) channels for voter communication. Both scarce economic resources

The aim of this paper is to examine whether the theory of cosmopolitan democracy provides a satisfactory solution to the boundary problem in democratic theory. I argue that David Held's version of cosmopolitan democracy rests on two incompatible principles: the all-affected principle and the all-inclusive principle. However, the theory does not need to presuppose both these principles; it req

This thesis tries to create a wider understanding for the complexity of friction in peacekeeping interventions. By connecting the concepts of friction and hybridity as well as the local and the international in a theoretical framework the thesis tries to concrete the complexity of peace processes. By applying the framework upon the UN peacekeeping mission MONUC in the Democratic Republic of the Co