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BACKGROUND: Given the high heterogeneity among breast tumors, associations between common germline genetic variants and survival that may exist within specific subgroups could go undetected in an unstratified set of breast cancer patients. METHODS: We performed genome-wide association analyses within 15 subgroups of breast cancer patients based on prognostic factors, including hormone receptors, t

When in use, a mobile terminal is often held in the hand by the user. However, conventionally terminal antennas are only evaluated in free space, disregarding the effects of user interaction. In this paper, the performance of a low-profile twoport multiple-input multiple-output (MIMO) antenna that offers wide symmetrical bandwidth and low correlation in free space is investigated in presence of a

Background: Treatment of mentally disordered offenders (MDOs) is challenging as their behavior and clinical conditions can be traced to a complex constellation of major mental disorders, substance use and antisocial lifestyle. Finding subgroups of these offenders, which could guide treatment and risk assessment, is desirable. There are few long-term, prospective studies of risk factors for persist

Background: Adolescent pregnancy and associated neonatal mortality are major global health challenges. In low-income settings where 90% of the 21 million global adolescent pregnancies occur, half are unintended and a fifth experience unsafe abortion. In Kenya, Uganda, and Tanzania, the survival patterns of neonates born to adolescents are unclear.Objectives: To assess survival patterns among neona

Strain and interactions at grain boundaries during solid-phase crystallization are known to play a significant role in the functional properties of polycrystalline materials. However, elucidating three-dimensional nanoscale grain morphology, kinetics, and strain under realistic conditions is challenging. Here, we image a single-grain growth during the amorphous-to-polycrystalline transition in tec

We present a new, scalable alternative to the structured singular value, which we call ν, provide a convex upper bound, study their properties and compare them to ℓ1 robust control. The analysis relies on a novel result on the relationship between robust control of dynamical systems and non-negative constant matrices.

Control systems can show robustness to many events, like disturbances and model inaccuracies. It is natural to speculate that they are also robust to sporadic deadline misses when implemented as digital tasks on an embedded platform. This paper proposes a comprehensive stability analysis for control systems subject to deadline misses, leveraging a new formulation to describe the patterns experienc

The policy used to implement a control algorithm in a real-time system can significantly affect the quality of control. In this paper, we present a method to adapt the controller implementation, with the objective to improve the system’s performance under real-time faults. Our method compensates for missing state updates by adapting the controller parameters according to the number of consecutivel

A wideband compact series-fed patch subarray is proposed for 79 GHz multiple-input multiple-output (MIMO) radar. The proposed subarray is, for the first time, loaded with stacked micro-vias (SMVs). Two sets of patches in the subarray are fed 180-degrees out-of-phase. A low-cost, high-resolution multilayer PCB technology, called “Any-Layer PCB”, is used to implement the SMVs, which cannot be done b

Homogeneous Charge Compression Ignition (HCCI) is a promising but challenging combustion engine concept. The potential for good fuel economy and low emissions is high but the transient performance required for automotive applications presents a few problems still to be solved. The focus of this work is identification of the process dynamics. An ARX type model is fitted to input-output data. A meth

Homogeneous Charge Compression Ignition (HCCI) combustion lacks direct ignition timing control, instead the auto ignition depends on the operating condition. Since auto ignition of a homogeneous mixture is very sensitive to operating condition a fast combustion timing control is necessary for reliable operation, the ignition timing control design requiring appropriate models and system output vari

This paper offers a two-zone, physical, NOx model with low computational cost, implemented in C on an embedded system. The model is able to compute NOx-emission formation with high time resolution during an engine cycle. To do this the model takes cylinder pressure and injected fuel amount as inputs and produces NO concentration as output. The model as such is not new, nevertheless the physical ba

This study aimed to disentangle the influence of information status and referential form on the distribution of gestures in sustained discourse. Previous research shows that new/less accessible rather than old/more accessible information, expressed by rich rather than lean referential forms, is more likely to be accompanied by gestures. However, earlier studies have drawn on correlational results.

Objectives The primary aim of the present study was to investigate the putative excess mortality by suicide in suicide attempters. As a secondary aim, we investigate excess mortality in specific, clinically relevant subgroups: individuals with repeated suicide attempts (RA); individuals who used violent method at the attempt (VA); and those who scored high on the Suicide Intent Scale (HS) at the t

This paper shows how a channel sounder can be built with National Instruments (NI) Universal Software Radio Peripheral (USRP) equipment, featuring onboard FPGA processing and utilizing open-source tools. Compared to other USPR-based channel sounders, our design eases the requirements on the data link between the USRP and the host, limits the measurement data size, and increases the signal-to-noise

BACKGROUND: Lead exposure has been associated with increased incidence of adverse clinical cardiovascular outcomes. Atherosclerosis has been suggested as one of the underlying mechanisms, and findings from experimental studies support this, but human data are scarce. OBJECTIVES: Our objective was to determine the association between environmental lead exposure based on blood lead (B-Pb) concentrat

This thesis studies two families of methods for finding zeros of finite sums of monotone operators, the first being variance-reduced stochastic gradient (VRSG) methods. This is a large family of algorithms that use random sampling to improve the convergence rate compared to more traditional approaches. We examine the optimal sampling distributions and their interaction with the epoch length. Speci

Cloud computing has quickly grown to become an essential component in many modern-day software applications. It allows consumers, such as a provider of some web service, to quickly and on demand obtain the necessary computational resources to run their applications. It is desirable for these service providers to keep the running cost of their cloud application low while adhering to various perform

BACKGROUND: Several studies have reported on the use of intraoperative parathyroid hormone (ioPTH) measurements during parathyroidectomy (PTX) for renal hyperparathyroidism (rHPT), but there is no consensus on whether it is helpful and, if so, what protocol should be used. Therefore, the literature was systematically reviewed to assess a correlation between ioPTH and early postoperative parathyroi