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Background: The rate of biological ageing is individual and represents the steady decrease in physiological and mental functions. Adverse social factors have been shown to influence this process. Self-perceived early ageing (SEA) might be a useful indicator of early biological ageing and increased mortality risk. The aim of this population-based study was to identify markers of SEA, including telo

Popular Abstract in Swedish Små partiklar i form av vätska eller fast material mellan 0.001 till 100 µm i diameter, kan sväva i luften och kallas då aerosolpartiklar. De påverkar direkt på klimatet genom att reflektera solstrålar ut till rymden. Detta gör att vi får ett kallare klimat. Indirekt kan de påverka klimatet genom att verka som kondensationskärnor vid molnbildning. Med detta påverkar de The aim of this work was to study atmospheric aerosols, focusing on the chemical composition, the morphology and the origin of the aerosol in the upper troposphere and lowermost stratosphere. An aerosol sampler was developed for this purpose. A new method for quantitative analysis of the major components of the aerosol, i.e. C, N and O was developed, and methodologies for single-particle analysis

The use of passive house technique has been used in a new wood framed building in Sweden. Besides the positive effect of reduced energy need, highly insulated wooden houses often have a higher risk of moisture and mould problems. The reason is that critical positions is more exposed to higher relative humidity compared to ordinary houses with thinner insulation. To investigate if an external wall

Structural and mechanistic aspects of orthoplatination of acetophenone and benzaldehyde oximes by the platinum(II) sulfoxide and sulfide complexes [PtCl2L2] (2, L = SOMe2 (a), rac-SOMePh (b), R-SOMe(C6H4Me-4) (c), and SMe2 (d)) to afford the corresponding platinacycles cis-(CS)-[Pt-II(C6H3-2-CR'=NOH-5-R)CI(L)] (3, R, R' = H, Me) have been investigated. The reaction of acetophenone oxime with sulfo

Rationale: A microdeletion at locus 15q13.3 is associated with high incidence rates of psychopathology, including schizophrenia. A mouse model of the 15q13.3 microdeletion syndrome has been generated (Df[h15q13]/+) with translational utility for modelling schizophrenia-like pathology. Among other deficits, schizophrenia is characterised by dysfunctions in prefrontal cortical (PFC) inhibitory circu

ackground: The separate spheres, in which men dominate the public sphere of politics, arts, media, and wage work and women dominate the private sphere of unpaid production and caring, is a powerful configuration in much social theory (including Parsons, Becker, and Goode), which posited that with industrialization, family structures and activities would converge towards the nuclear family with strBackground: The separate spheres, in which men dominate the public sphere of politics, arts, media, and wage work and women dominate the private sphere of unpaid production and caring, is a powerful configuration in much social theory (including Parsons, Becker, and Goode), which posited that with industrialization, family structures and activities would converge towards the nuclear family with st

Aims: Patterns of species richness, such as the remarkable biodiversity of tropical regions, have been documented and studied for centuries. However, their underlying evolutionary and ecological causes are still incompletely understood. A commonly stated paradigm in the literature is that high richness in some habitats is directly caused by one of three competing explanations: (1) greater time-for

När en väljare röstar med andras beteende i åtanke och politikutfall i sikte är det en "strategisk" röst. Den här studien relaterar väljares strategiska överväganden till olika steg i regeringsbildningsprocessen: att ta plats i parlamentet, ingå i regering, och påverka politikutfallet. Detta innebär att väljaren ibland tänker som ett parti på vad rösten kan få för konsekvenser. Utifrån detta perspIf a voter defects from preference under the consideration of policy outcomes and others' behavior, it is a "strategic vote". This thesis relates voters' strategic considerations to the government formation process: the chances for a party to gain seats, enter office, and affect overall policies. This implies that voters sometimes think like parties on the governmental consequences of the vote. Fr

Ciliary neurotrophic factor (CNTF) promotes photoreceptor survival but also suppresses electroretinogram (ERG) responses. This has caused concerns about whether CNTF is detrimental to the function of photoreceptors because it is considered to be a potential treatment for retinal degenerative disorders. Here we report that the suppression of ERG responses is attributable to negative regulation of t

OBJECTIVE: Treatments have failed to delay or stop the autoimmune process, preceding onset of type 1 diabetes. We investigated if autoantigen-specific treatment with alum-formulated glutamate decarboxylase (GAD-Alum) was safe and affected progression to type 1 diabetes in children with islet autoimmunity.METHODS: In an investigator-initiated, double-blind, placebo-controlled clinical trial, non-di

Inhibitory control refers to the ability to stop impulses in favor of more appropriate behavior, and it constitutes one of the underlying cognitive functions associated with cognitive flexibility. Much attention has been given to cross-species comparisons of inhibitory control; however, less is known about how and when these abilities develop. Mapping the ontogeny of inhibitory control in differen

BACKGROUND: To have an impact on the population's health, preventive interventions have to reach a large proportion of the intended population. Digital solutions show potential for providing wider access to fall preventive exercise. However, there is a lack of knowledge about how to reach the target group. The aim of this study was to describe the recruitment process used in the Safe Step randomis

Alzheimer's disease is a neurodegenerative condition which involves heavy neuronal cell death linked to oligomers formed during the aggregation process of the amyloid β peptide 42 (Aβ42). The aggregation of Aβ42 involves both primary and secondary nucleation. Secondary nucleation dominates the generation of oligomers and involves the formation of new aggregates from monomers on catalytic fibril su

[The project Millora 2.0: Results 2018–2022] Based on repeated yearly surveys of the vascular plant flora in 120 hectar plots in the province of Scania, southernmost Sweden, analysed in combination with speciesspecific traits and ecological indicator values (EIVs), changes in the flora and vegetation over the last four years are reported. Many of the changes observed, such as significant increasesBased on repeated yearly surveys of the vascular plant flora in 120 hectar plots in the province of Scania, southernmost Sweden, analysed in combination with speciesspecific traits and ecological indicator values (EIVs), changes in the flora and vegetation over the last four years are reported. Many of the changes observed, such as significant increases in lightdemanding, shortlived, pollinatorind

Syfte: Uppsatsen ser till vilken påverkan Instagram har på konsumenters resekonsumtion. Syftet med arbetet är att analysera och skapa en djupare insikt i hur studenters resekonsumtion påverkas av de bilder som publiceras på Instagram och hur dessa i sådant fall kommer till uttryck. Vi studerar också i vilket steg i beslutsprocessen som Instagram påverkar resekonsumtionen mest. Metod: Uppsatsen äPurpose: This paper deals with the impact Instagram has on consumers travel consumption. The aim of this paper is to analyse and create a deeper insight into how students travel consumption are affected by the pictures published on Instagram and how they are expressed. We also examine in which step of the buyer decision process Instagram affects travel consumption the most. Method: This study use

I september 2014 antog FN:s säkerhetsråd resolution 2178, i ett försök att stävja strömmen av frivilliga som söker sig till terrorstämplade grupper i främst Syrien och Irak. Resolutionen uppställer krav på medlemsstaterna att införa nationell lagstiftning för att tackla problemet. Samtidigt definieras inte vad som ska anses utgöra terrorism och det saknas en geografisk eller tidsmässig avgränsningIn September 2014 the UN Security Council adopted resolution 2178 in an attempt to prevent the flow of so-called foreign terrorist fighters, a term referring to all foreign recruits who voluntarily join the ranks of UN-designated terrorist organisations. The resolution imposes upon member states far-reaching legal obligations to strengthen their domestic criminal laws. The scope of the resolution

Vetenskapen har gjort att vi kan idag kan känna igen ett sjukdomstillstånd, eller följa ett sjukdomsförlopp genom att titta på dess biologiska fingeravtryck. För att man ska kunna upptäcka och tolka ett sådant fingeravtryck behöver man ett högteknologiskt redskap; microarray. Ett biologiskt fingeravtryck utgörs av en uppsättning ämnen, eller biomarkörer, som i olika kombinationer och koncentrationAnalyses of biological samples today include protein microarray, a high-throughput technology that can be used for protein expression profiling, targeting disease related biomarkers. Affinity microarray utilises scFv antibodies, fixed in an ordered pattern on a solid support. Albeit high biocompatibility and sensitivity, this technique causes randomised antibody orientation, which could negatively

To increase productivity in the rail industry, the Swedish Transport Administration (Trafikverket) has decided to increase the percentage of projects procured as turnkey projects. Two recent projects, a railway switch exchange and a track replacement has been contracted as turnkey projects and the purpose of this project is to conduct an experience feedback of them. The goal is to find and enlight

Lagen om anställningsskydd infördes år 1974 för att trygga anställningen för alla enskilda arbetstagare på den svenska arbetsmarknaden. Tidigare hade arbetstagarnas rättigheter reglerats i kollektivavtal och endast vissa arbetstagares rättigheter var reglerade i lag. Några regler som infördes i 1974 års lag var bland annat saklig grund för uppsägning enigt 7 § LAS. För att saklig grund skulle anseThe Employment Protection Act from 1974 was implemented in to Swedish law as a way to secure the employments of the employees. Before the implementation of the Act, the rights of the employees were regulated in collective agreements. By then there were only some rights regulated in the law. Some of the regulations that were implemented in to the Employment Protection Act was the 7§. The 7 § states