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To develop treatments for currently uncurable neurological disorders, more knowledge is needed of the involved neural circuits and changes in gene expression. The padlock probe technique, in which linear DNA probes are circularized and amplified when hybridized to their cDNA target sequence, has previously been used for both multiplexed gene detection and neuronal projection mapping in brain tissu
This project is about developing a new neighbourhood in Häljarp with a floodable wet land park as the core. After analysing the site and its surroundings, a number of strategies has been created to guide the design process. The strategies are divided into three categories; adapt to the site, liven up the community and complementing the area. This landed in a carefully considered proposal. The desi
Bröstcancer är den vanligaste cancerformen bland kvinnor. För att kunna utröna viktiga mekanismer involverade i uppkomsten och framfarten av bröstcancer, och därigenom kunna utveckla nya behandlingsformer, är det viktigt att ha tillgång till tillförlitliga och enkla metoder för beredning och analys av cellprover. I Sverige förväntas uppemot var tionde kvinna att drabbas av bröstcancer innan 75 åTo expand knowledge on the mechanisms of breast cancer, the most prevalent cancer in women, the development of new and reliable technologies are of great interest. Phosphoproteome analysis of breast cancer cell lines can reveal important cellular processes active in different subtypes of the disease, and contribute to the understanding of breast cancer progression. Here, different sample preparati
Long waiting periods for asylum seekers is a problem in most European countries and the effort to harmonise the refugee politicy within the union has brought this question to the point. Everyone agrees that the asylum process has to be made more effective, also Sweden. Medical research shows that asylum seekers in Sweden are particularly exposed to mental and physical unhealthiness. My ambition wi
There is today an ongoing debate about Fair Trade and its consequences. The way to reach an understanding about the producers lives is important if the future will be liberated from the uneven access to the market. Today the free market is dominated by a few multinational companies and for poor producers there is no chance to compete at the same level. If industrial countries continue to exploit d
This thesis covers optimizing the first phase of the start-up of a thermal power plant using Nonlinear Model Predictive Control (NMPC) and state estimation using an Unscented Kalman Filter (UKF). The start-up has been optimized in regards to time and fuel usage. The thesis is done as a joint project between Vattenfall and Modelon. Both NMPC and UKF are nonlinear methods and require a model of the
Syftet med denna studie var att undersöka psykodynamiska psykoterapeuters subjektiva upplevelser och erfarenheter av vändpunkter i psykoterapi. Detta gjordes med en kvalitativ fenomenologisk-hermeneutisk ansats, med Tematisk analys som metod. Sex psykodynamiska psykoterapeuter och två som befann sig under utbildning till psykoterapeut intervjuades, och en psykoterapeut valde att skriva ner sin berThe purpose of this study was to investigate the psychodynamic psychotherapists´ subjective experiences and the experiences of the turning points in psychotherapy. This was done with a qualitative phenomenological-hermeneutical approach, with the Thematic analysis method. Six psychodynamic psychotherapists and two who were in psychotherapy training were interviewed, one left a written text. Six ma
This research gives a special attention to CSR audit in China, from both theoretical and practical perspectives. The research starts with the analysis of theoretical foundation that underlies the emergence and development of CSR and CSR audit. Both stakeholder theory and principal-agent theory are applicable to explain it. In the context of these two theories, the corporate management is not only
A numerical formulation is provided for secondary ice production during fragmentation of freezing raindrops or drizzle. This is obtained by pooling laboratory observations from published studies and considering the physics of collisions. There are two modes of the scheme: fragmentation during spherical drop freezing (mode 1) and during collisions of supercooled raindrops with more massive ice (mod
Objective: To evaluate the effect of dosage on the metabolic response to vegetables added to a mixed lunch meal, and to relate the amounts to the tripartite plate model. Carrots were chosen as an example, and the carrots were blanched, frozen and boiled to include possible effects of processing and cooking. The effects of carrots steeped in lactic acid, as produced at fermentation, were also studi
Removal of the native surface oxide from steel is an important initial step during vacuum brazing. Trace and alloying elements in steel, such as Mn, Si, and Ni, can diffuse to the surface and influence the deoxidation process. The detailed surface chemical composition and grain morphology of the common stainless-steel grade 316L is imaged and spectroscopically analyzed at several stages of in-vacu
As a classical polymer acceptor material, N2200 has received extensive attention and research in the field of polymer solar cells (PSCs). However, the intrinsic properties of ground- and excited-states in N2200, which are critical for the application of N2200 in PSCs, remain poorly understood. In this work, the ground- and excited-state properties of N2200 solution and film were studied by steady-
Simple roles for photoreception are likely to have preceded more demanding ones such as vision. The driving force behind this evolution is the improvement and elaboration of animal behaviors using photoreceptor input. Because the basic role for all senses aimed at the external world is to guide behavior, we argue here that understanding this "behavioral drive" is essential for unraveling the evolu
Safe long-term storage of spent nuclear fuel (SNF) is one of the main issues in the field of nuclear safety. Burn-up credit application in criticality analysis of SNF reduces conservatism of usually used fresh fuel assumption and implies a positive economic impact for the SNF storage. Criticality calculations of spent nuclear fuel in the CONSTOR® RBMK-1500/M2 cask were performed using pre-generat
One of the main challenges as the market for fully commercial electrified vehicles quickly expands is predicting the electromagnetic interference (EMI) in traction voltage systems (TVSs) in differential mode (DM) and common mode (CM). The number of subsystems connected to vehicle TVSs is increasing, and thus, so are the electromagnetic compatibility (EMC) requirements. These requirements should ma
While maximum standard absolute adjectives (such as straight) typically have a precise meaning (e.g., ‘perfectly straight’), they are also regularly used imprecisely (e.g., to mean ‘straight enough’). The current study investigates how contextual expectations of precision and a visual referent’s conceptual distance from an ideal maximum standard influence the processing effort of precise and impre
The prospect of Turkish accession to the EU has sparked controversy in many of the member countries. It has highlighted the different ways in which European as well as Turkish identity is being defined in the debate, with some politicians seemingly trying to draw on old prejudices in order to make the case against membership. By utilising discourse analysis as advocated by Thomas Diez, this thesis
Fluorescence sensing plays an increasingly important role in biology and biomedicine. For many practical applications of fluorescent probes, an “off-on” response is preferred. The question of how fluorescence quenching/enhancement occurs is fundamental and of high importance for application and design of new fluorescent probes. The sensing mechanism of an aminorhodamine (TMARh) pH probe is investi
Dissolved organic matter (DOM) drives many fundamental biogeochemical processes (e.g., carbon storage, nutrient cycling, and soil development) in forest soil. However, the molecular-level characteristics of DOM derived from different types of tropical forest soils are poorly understood. Here, water samples at different soil depths (0, 20, and 40 cm) from tropical legume (Acacia auriculiformis, AA)
