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När vi lär oss av nya erfarenheter är minnen till en början detaljrika och kontextspecifika, och är lättare att plocka fram när inlärningssituationen återinrättas. Med tiden och upprepade framplockningar tenderar dock vissa minnen att förlora kontextuella detaljer (dekontextualiseras), och bli åtkomliga för framplockning i nya situationer (generaliseras). Denna studie gjordes i syfte att undersökaWhen we learn from new experiences, memories are initially detailed and context-specific, making them easier to retrieve when the learning situation is reinstated. Over time and repeated retrievals, however, some memories tend to lose contextual details (decontextualize) and become accessible for retrieval in new situations (generalize). This study aimed to investigate under which circumstances th

PCDD/Fs and dl-PCBs, or more commonly referred to as dioxin and dioxin like substances are compounds present in our surrounding environment. As some congeners of these have been shown to be toxic, they are regulated under the Stockholm Convention. As dioxins are persistent in biota and have lipophilic properties they are seen accumulating in lipid rich fish in the Baltic, one of the affected speci

Klimatförändringarna, energikrisen och en ökande efterfrågan på el har uppmärksammat behovet av en hållbar omställning av energisystemet. Havsbaserad vindkraft spelar en viktig roll i denna omställning och förväntas expandera kraftigt globalt, i EU och i Sverige. Samtidigt möter projekt stort lokalt motstånd. Trots att svenskar generellt visar högt stöd för vindkraft så har en majoritet av de senaClimate change, the energy crisis of 2022-2023, and estimations of future electricity demands have stressed the necessity for a rapid transition of the energy system. Offshore wind energy plays an important role in this transition, and is expected to expand considerably on a global level, in the EU and in Sweden. While Swedes show high support of wind energy, a majority of recent projects have bee

Tidigt under åren i arkitektskolan lär vi oss att forma och utforska våra egna kreativa processer. Dessa blir djupt personliga, och i detta projekt vill jag försöka formulera och utforska mitt sätt att arbeta. Under min studietid har jag upplevt att de största problemen jag haft under designprocessen varit att jag tenderat att bli för självkritisk i ett tidigt skede, vilket har resulterat i låsninIn the early years of architecture school, we learn to shape and explore our creative processes. These become deeply personal, and in this project I want to try defining and exploring my way of working. During my time as a student, I have experienced the biggest problems I had during the design process were that I tended to be too self-critical at an early stage, which resulted in blockages in the

This thesis, initiated by Thule Group, investigated how an ultra-lightweight roof top tent could be developed to improve and simplify the user experience during installation and use. The aim of the project was to design a roof top tent for two people, which could be handled and mounted on a car by one person. During the project, Double Diamond together with a human-centred design approach was use

Background and purpose — Traditional surgery forarthritis of the distal radioulnar joint (DRUJ), which typicallyinvolves resecting the ulnar head, is being increasingly challengedby newer techniques, such as prosthetic ulnar headreplacement. The aim of our prospective cohort study was toinvestigate the clinical and patient-reported functional results,up to 2 years postoperatively, among patients w

Background: The coronavirus disease-2019 (COVID-19) pandemic posed pronounced challenges in the care of lung transplant (LTx) recipients. Global variations in containment strategies and the introduction of messenger ribonucleic acid (mRNA) vaccines have sparked extensive debate in both scientific and public arenas. Methods: This retrospective study compared outcomes among LTx recipients in Denmark

The lifelong risk of stroke following adverse pregnancy outcomes, and potential causality, are unknown. This study examined five major adverse pregnancy outcomes and long-term risk of stroke in a large population-based cohort. Methods A national cohort study was conducted of all 2 201 393 women with a singleton delivery in Sweden during 1973–2015, followed up for stroke through 2018. Cox regressio

Background Primary ciliary dyskinesia (PCD) represents a group of rare hereditary disorders characterised by deficient ciliary airway clearance that can be associated with laterality defects. We aimed to describe the underlying gene defects, geographical differences in genotypes and their relationship to diagnostic findings and clinical phenotypes. Methods Genetic variants and clinical findings (a

PURPOSE: This study aimed to examine the associations between the intake of high- and low-fat fermented dairy (cheese and fermented milk), their proteomic profiles, and mortality risk.METHODS: This cohort study included 25,187 participants (mean age 57.7 years, 60.9% females). Fermented dairy intake was assessed by a modified diet history method. In a random subset of this cohort (n = 4359), we co

Background: Studies on long-term exposure to air pollution at high levels suggest an association with increased risk of metabolic syndrome (MetS). We aimed to study this relationship at very low levels, less well-studied, yet of public health importance. Methods: The Swedish CArdioPulmonary bioImage Study (SCAPIS) consists of randomly selected subjects aged 50–64 years from six large cities in Swe

Background: Type 2 diabetes (T2D) is associated with increased risk of complications after breast cancer surgery. This study investigated systemic and surgical-site postoperative complications and the risk of early and late breast cancer recurrence and mortality, overall, and according to T2D status. Methods: From the Danish Breast Cancer Group (DBCG) and Danish registries, a cohort of women with

BACKGROUND: Post-acute sequelae of SARS-CoV-2 infection, or long COVID, include diverse symptoms and remain a major concern worldwide. This study investigates the occurrence of depression, anxiety, fatigue, and headache 1 year prior to the COVID-19 pandemic (2019), 12 months prior to, and 6 months after long COVID diagnosis in individuals diagnosed with long COVID and matched population-based cont

Background: We set out to profile the immune mechanisms active in treatment-naïve oligoarticular JIA (oJIA) to improve the knowledge of its immunopathogenesis, to identify potential biomarkers that can aid diagnosis, predictions and that correlate with clinical disease parameters. Methods: Using Olink proteomics (inflammation panel measuring 92 markers), we defined and compared the inflammation pr

Background: Amyotrophic lateral sclerosis (ALS) is invariably fatal but there are large variations in the rate of progression. The lack of predictability can make it difficult to plan clinical interventions. This includes the requirement for gastrostomy where early or late placement can adversely impact quality of life and survival. Methods: We designed a model to predict the timing of gastrostomy

Objective: To investigate the development of sexual activity, sexual function, and body image in women with primary vulvar cancer from the time of diagnosis to 24 months after the end of treatment. Methods: This nationwide prospective cohort study assessed health-related quality of life in women with newly diagnosed vulvar cancer using validated patient-reported outcome measures (EORTC-QLQ-VU34 [E

Objective Individuals with SLE commonly report chest pain or discomfort. We performed cardiovascular magnetic resonance (CMR) to differentiate coronary artery disease (CAD), coronary microvascular dysfunction (CMD), pericarditis and myocarditis in individuals with SLE who presented with chest symptoms. We also assessed the clinical utility of CMR. Methods Adults with SLE were included if reporting

Introduction: Food systems strongly influence both human and planetary health. Unhealthy diets aremajor risk factors for chronic disease and mortality, while food production contributes substantially togreenhouse gas emissions (GHGE), and other negative environmental impacts. Adopting moresustainable dietary patterns, such as the EAT-Lancet diet, has been proposed as part of the solution, butuncer

Background Although the role of smoking as a risk factor for emphysema in α1-antitrypsin deficiency (AATD) is well known, never-smokers with severe AATD may also develop lung disease, ranging from mild asymptomatic disease to severe emphysema. Methods We performed a cross-sectional and observational study to analyse the characteristics of the population of never-smoker severe AATD (genotype) indiv

Den allmänna rösträtten har genom historien varit något som människor be-hövt kämpa för. Idag kan man tycka att det ska vara en självklarhet att alla människor är berättigade lika och allmän rösträtt, men så har fallet långt ifrån alltid varit. Så sent som 1965 såg man till att alla svarta medborgare i USA tilläts utöva sin rätt att rösta. I Sverige, Storbritannien och USA finns det många likhetUniversal suffrage has throughout history been something people have had to fight for. Today, it may seem self-evident that all people are equally entitled to universal suffrage, but this has far from always been the case. As recently as 1965, measures were taken to ensure that all Black citizens in the United States were allowed to exercise their right to vote. In Sweden, Great Britain, and the