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Epilepsy is a devastating neurological disorder characterized by synchronous neuronal activity, which manifests as epileptic seizures. It usually develops after an initial insult, such as head trauma or stroke, which triggers the epileptogenic process. During epileptogenesis, the affected brain regions undergo multiple changes in connectivity and gene expression, and among the most affected genes
Operation med konstgjorda ledproteser i höft och knä ger generellt mycket lyckade resultat. Fortfarande förekommer dock lossning och slitage av komponenterna som ett problem, och alla patienter blir inte fullt nöjda. I ett flertal forskningsprojekt studerar vi faktorer av betydelse för fixation och funktion av proteskomponenterna. Vi utvärderar hur man optimerar de biomekaniska ledförhållandena viTotal joint replacements, both in the hip and knee, are generally very successful operations. Still, however, component loosening as well as wear remains a problem, and all patients are not fully satisfied with their new joint. In a number of ongoing investigations, we are studying different factors involved in the fixation and function of the prosthesis components. We are exploring how to optimiz
Laboratoriet för metabola störningar och leversjukdomar leds av Philipp Kaldis, som är professor vid Institutionen för kliniska vetenskaper och vice koordinator för Lunds universitets Diabetescentrum (LUDC). Nya data tyder på att upp till 30% av befolkningen lider av leversjukdomar inklusive icke-alkoholorsakad fettleversjukdom (NAFLD), som kan vidareutvecklas till icke-alkoholorsakad steatohepatiThe metabolic disorders and liver disease laboratory is headed by Philipp Kaldis, who is a Professor in the Department of Clinical Sciences and a vice-coordinator of the Lund University Diabetes Centre (LUDC). Recent data suggests that up to 30% of the population suffers from liver diseases including non-alcoholic fatty liver disease (NAFLD), which can further develop to non-alcoholic steatohepati
MultiPark är ett translationellt forskningsnätverk som sträcker sig från preklinisk forskning till studier av livssituationer för patienter med Alzheimers och Parkinsons sjukdom samt relaterade hjärnsjukdomar. Vi syftar inte bara till att förbättra patienternas kroppsfunktion utan även deras aktivitet och delaktighet. MultiPark bygger på ett starkt samarbete mellan Lunds universitet och Skånes uniMultiPark (Multidisciplinary research focused on Parkinson's disease) is a translational programme that ranges from experimental pre-clinical research to studies on the life situation of patients with neurodegenerative disorders. Our programme not only aims at improving the overall function of patients, but also their acitivity and participation. This initiative relies on solid interactions betwee
Artros, vår vanligaste ledsjukdom, orsakar smärta och funktionsnedsättning och drabbar främst knä, höft och fingerleder. Dagens behandling är fokuserad på smärtlindring, sjukgymnastik och eventuell ledersättning. Vid ledskada och artros bryts broskproteiner ner, och ledskador är en riskfaktor för artros, men mekanismerna som leder fram till artros är till stor del okända. Vi studerar de molekyläraOsteoarthritis (OA), the most common joint disease, causes pain and disability and mainly affects the knee, hip and finger joints. Treatment focuses on pain relief, physical therapy and eventually prosthesis. Cartilage proteins are degraded after joint injuries and in OA; joint trauma is a risk factor for OA, but the mechanisms leading to OA are mainly unknown. We study the molecular and structura
Skissernas Museum – Museum of Artistic Process and Public Art is a unique art museum that focuses on the artistic creative process. It features the world’s largest collection of sketches, models and preparatory work for Swedish and international public art. The large exhibition rooms hold modern and contemporary art – from small pencil drawings to colourful, monumental paintings and large-scale pl
Syftet med detta examensarbete är att öka kunskapen kring hur AI inom fysisk Retail får konsekvenser för konsumenters värdeskapande. Vikten av kompetens och kunskap i kombination med teknik betonas för att möjliggöra förbättrade kundupplevelser inom fysisk retail. Kundens köpbeslut påverkas främst av människors kunskap och kompetens, där tekniken kompletterar och stöttar den mänskliga interakThe purpose of this thesis is to increase knowledge about how AI in physical Retail has consequences for consumers' value creation. The importance of competence and knowledge in combination with technology is emphasized to enable improved customer experiences in physical retail. The customer's purchase decision is primarily influenced by people's knowledge and competence, where tech
The current process of issuing industrial and mineral licenses is complex and time consuming. More specific, industry establishment generally makes environmental pollution. Such negative impact on environment is due to not using proper information and mechanisms for site selection and license issuance. This research suggests a new process/method based on WebGIS enable e-government to simplify the
• Meliha C Kapetanovic (gruppledare) huvudforskningslinje är att studera olika aspekter av vaccination vid inflammatoriska reumatiska sjukdomar. Andra forskningsområden är remission vid reumatoid artrit och gikt. Doktorander Jon Einarsson, Johanna Nagel and Per Nived är involverade i dessa projekt. • Elisabet Lindqvist Johan K Wallman, Tor Olofsson och Elisabet Mogard (doktorand) ansvarar för SPAR• Meliha C Kapetanovic (group leader) research area includes vaccinations in patients with inflammatory rheumatic diseases, remission in patients with RA and gout. PhD students Jon Einarsson, Johanna Nagel and Per Nived are involved in these projects. • Elisabet Lindqvis’s Johan K Wallman, Tor Olofsson and Elisabet Mogard (physiotherapist, PhD-student) are responsible for SPARTAKUS, a crossectiona
Abstract in UndeterminedThis paper describes a method for assessing the effectiveness in the steps of the learning cycle: the 1st loop with reporting - analysis - decision - implementation - follow-up, and the 2nd loop on an aggregated basis. For each step, the dimensions considered the most relevant for the learning process (scope, quality, timing and information distribution) and for each dimens
The aim of the thesis is to research and compare the situation of management practices in Japanese companies in Japan and in Japanese companies abroad after a joint venture termination, particularly in Sweden. The changing in management style when Japanese companies go abroad is a highly researched topic. However, not that much research has been done on the Japanese companies in Sweden, specifical
Artificial Intelligence in Cardiothoracic Science was funded 2006. Traditionally, medical decisions are based on the combined strength of clinical facts and the experience of the clinician. A growing understanding of the molecular, genetic and biochemical basis of diseases have greatly increased the degree of complexity in medical decision-making. To identify risk factors in medical registers, a n
