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Resistance to activated protein C (APC) is a major cause of familial thrombophilia, and can be corrected by an anticoagulant activity expressed by purified factor V. We investigated linkage between APC resistance and the factor V gene in a large kindred with familial thrombophilia. Restriction fragment length polymorphisms in exon 13 of the factor V gene were informative in 14 family members. The

Abstract in Spanish El objetivo de este trabajo es reflexionar acerca de las diferentes estrategias de desarrollo que, desde la década de 1990, se vienen construyendo en territorios rurales del norte de Argentina. Para ello, presentamos desde una perspectiva comparativa tres casos de estudio localizados en el noroeste y nordeste del país: la Quebrada de Humahuaca (Jujuy), el departamento de San Ca

Short fatigue cracks are known to have a growth behaviour different from that of long cracks, the latter well predicted by linear elastic fracture mechanics. Short cracks can grow at high rates at load levels well below the threshold value for long cracks, before entering into the long crack region, or arrest and become nonpropagating cracks. The growth behaviour of short cracks is strongly influe

Chromosomal aneuploidy, that is, numerical chromosome aberrations, is one of the molecular hallmarks of cancer. However, when neoplasms are studied with sequencing- and array-based approaches, chromosome numbers and ploidy states are typically inferred from bulk DNA data. Furthermore, published molecular estimates of neoplasia-associated aneuploidy often also include genomic imbalances resulting f

Immigration status as a ground of making distinctions that might be in violation of the right to non-discrimination, is conceptually underdeveloped. This gap is addressed by explaining how the European Court of Human Rights has chosen to use arguments shaped by factual and legal/normative elements to reason under Article 14 of the European Convention on Human Rights. One such argument concerns the

Chapter 7, written by Vera Sadovska, Oksana Mont and Yuliya Voytenko Palgan, explores the economic sustainability of food-sharing initiatives (FSIs). Bringing together insights from a systematic literature review and empirical research in Barcelona, the chapter examines the economic challenges FSIs face, such as managing operational costs, obtaining funding and dealing with regulatory complexities

Rationale: Patients with obesity hypoventilation syndrome (OHS) have high risk of hospitalization, which might be decreased by home mechanical ventilation (HMV). Objectives: To evaluate annualized hospitalization rate (AHR) and changes in AHR in patients with OHS starting HMV and explore if there were any differences in AHR by starting HMV acutely or electively. Methods: This was a population-base

Digitalization poses significant challenges to the EU VAT system, as it does in other areas of law. These challenges can be broadly divided into two main categories: those stemming from transformations in the economy, and those related to the legislative responses to these changes. In the VAT context, the first category includes the growing volume of transactions—particularly cross-border transact

Magnesium (Mg) is an abundant metal which has been used in aviation, medicine, hydrogen energy storage, etc. However, Mg can be rather reactive, and therefore an improved understanding of corrosion and oxidation mechanisms can enhance the efficiency of these processes to control and widen applications. The study presented here investigates the mechanisms of oxidation from the initial to full monol

Caenorhabditis nematodes, particularly the well-known Caenorhabditis elegans, have challenged early views of them as hard-wired by demonstrating diverse learning and memory capabilities. This cognitive repertoire, developed with just several hundred neurons, highlights the evolutionary importance of cognitive traits. In this study, we examine the relationship between learning, development, reprodu

BACKGROUND: The ongoing TANGO2 (Telephone Assisted CPR. AN evaluation of efficacy amonGst cOmpression only and standard CPR) trial is designed to evaluate whether compression-only cardiopulmonary resuscitation (CPR) by trained laypersons is noninferior to standard CPR in adult out-of-hospital cardiac arrest. This pilot study assesses feasibility, safety, and intermediate clinical outcomes as part

Most state-of-the-art natural gas fired combined cycle (NGCC) plants are triple-pressure reheat cycles with efficiencies close to 60 percent. However, with carbon capture and storage, the efficiency will be penalized by almost 10 percent units. To limit the energy consumption for a carbon capture NGCC plant, exhaust gas recirculation (EGR) is necessary. Utilizing EGR increases the CO2 content in t

Temporära diplomatiska beskickningar mellan stater regleras internationellt genom ”The Convention on Special Mission”. Genom konventionen regleras också vilken typ av immunitet som gäller för ad hoc-diplomater. Temporära beskickningar har oftast ett specifikt syfte och verkar på uppdrag av en stat under en begränsad tidsperiod. Sverige har för närvarande inte anslutit sig till konventionen och harDiplomatic delegations sent by a state to conduct specific tasks are internationally referred to as special missions. This type of diplomacy is regulated through the Convention on Special Missions which also states the terms of immunity for the so-called ad hoc diplomats. Sweden has currently not ratified the convention and does not have any national regulation relating to special missions sent by

This thesis addresses the issue of customer relationship building in new small retail ventures with a particular focus on individual consumers and application of such relationship marketing concepts as trust, satisfaction, loyalty and value. This research rests upon a qualitative single-case study of a new German retail venture and assumes an interpretivist approach. The main method of inquiry enc