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The Late Emergence of the Socioeconomic Gradient in Adult Mortality: An Urban Phenomenon?

Previous research has shown that class differences in adult mortality in the study area emerged only in the mid-twentieth century. Such findings question a universal association between socioeconomic status and mortality. This chapter examines whether these class differences in adult mortality emerged at the same time in urban as in rural areas. The analysis shows that the social class gradient in

Social Media, Anti-Corruption Activism and Democratisation in Authoritarian Contexts : A Case Study of Uzbekistan

This article aims to examine the nexus between social media, anti-corruption activism and democratisation in authoritarian regime contexts. It will investigate the complex ways in which civil society actors utilise art and humour on social media platforms to engage in covert anti-corruption activism. In doing so, we will show how, in authoritarian contexts, digital (social media) activists creativ

Higher-order thinking e-assessment in online EFL courses : Swedish instructors' perceptions and experiences

Previous research indicates that higher-order thinking skills (HOTS) have an important role in L2 learning. In an online learning context, e-assessment tasks are ideally designed to target these skills. A recently conducted study by Johansson (2020) indicates that HOTS e-assessment is relatively common in Swedish online English as a Foreign Language (EFL) courses. Generally, instructors’ perceptio

Completion axillary lymph node dissection for the identification of pN2–3 status as an indication for adjuvant CDK4/6 inhibitor treatment : a post-hoc analysis of the randomised, phase 3 SENOMAC trial

Background: In luminal breast cancer, adjuvant CDK4/6 inhibitors (eg, abemaciclib) improve invasive disease-free survival. In patients with T1–2, grade 1–2 tumours, and one or two sentinel lymph node metastases, completion axillary lymph node dissection (cALND) is the only prognostic tool available that can reveal four or more nodal metastases (pN2–3), which is the only indication for adjuvant abe

Stimulation of χ transcription by a decamer‐dependent, synergistic mechanism

The intact SP6 χ promoter stimulated transcription 30 times more efficiently than did a control promoter consisting of a TATA motif as the only promoter element. Mutation of the SP6 χ promoter decamer in two positions reduced the transcriptional stimulation activity by over 90%. Promoters containing the SP6 χ promoter octamer or a consensus octamer in front of a TATA box were ineffective immunoglo

Effect of radiotherapy after mastectomy and axillary surgery on 10-year recurrence and 20-year breast cancer mortality : meta-analysis of individual patient data for 8135 women in 22 randomised trials

BACKGROUND: Postmastectomy radiotherapy was shown in previous meta-analyses to reduce the risks of both recurrence and breast cancer mortality in all women with node-positive disease considered together. However, the benefit in women with only one to three positive lymph nodes is uncertain. We aimed to assess the effect of radiotherapy in these women after mastectomy and axillary dissection.METHOD

Modulation of ERP responses by predictability of information in negated contexts

Modulation of ERP responses by predictability of information in negated contextsPrevious research has shown that language comprehension is incremental and that we can keep up with language input because we make predictions about the upcoming information [1]. If these predictions are confirmed, processing is facilitated. In event-related potential (ERP) studies, this facilitation effect appears in

IoET-SG : Integrating internet of energy things with smart grid

The term smart grid refers to an electrical grid system that incorporates a range of operating and energy initiatives including advanced metering, intelligent distribution boards and circuit breakers, load control switches and smart devices, and renewable energy resources. The incorporation of the internet of things (IoT) into the smart grid, called the internet of energy things-smart grid (IoET-S

The Galactic formation rate of eccentric neutron star-white dwarf binaries

Abstract in Undetermined n this paper we consider the population of eccentric binaries with a neutron star and a white dwarf that has been revealed in our galaxy in recent years through binary pulsar observations. We apply our statistical analysis method (Kim, Kalogera, & Lorimer 2003)and calculate the Galactic formation rate of these binaries empirically. We then compare our results with rate

Novel engineered peptides of a phage lysin as effective antimicrobials against multidrug-resistant Acinetobacter baumannii

Acinetobacter baumannii is a Gram-negative bacterial pathogen responsible for a range of nosocomial infections. The recent rise and spread of multidrug-resistant A. baumannii clones has fueled a search for alternative therapies, including bacteriophage endolysins with potent antibacterial activities. A common feature of these lysins is the presence of a highly positively charged C-terminal domain