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Konsten att leva länge-Föreställningar om livets förlängning i handböcker 1700-1930

Popular Abstract in Swedish Drömmen om evigt liv och evig ungdom är inte ny. Föreställningarna om vägen dit är ungefär desamma idag som för 300 år sedan. Men de tekniska möjligheterna har vidgat gränserna. Att förbli ung, eller åtminstone se ung ut, är ett ideal som växer sig allt starkare. Åldrande och död ska bekämpas, att hålla sig ung och att leva länge är viktigt. Det gäller att träna och skThe aim of this thesis is to explore discursive changes in conceptions of life course and ageing. In a sense the Life- Span embodies the boundaries of human existence, but furthermore, it symbolizes a discursive system with distinctive symbols and meaning, that regulates and re-construct a cultural context. Hence, a cultures notion of the Life-Span also reveals its images and apprehensions of agei

China's "Great Proletarian Information Revolution" of 1966-1967

By the autumn of 1966, the PRC government had enjoyed seventeen years of uninterrupted and complete domestic information dominance. Independent collection of information was hampered by way of a CCP culture of secrecy and successfully enforced regimen of information curtailment. Of the changes in the political landscape triggered by Mao Zedong’s August 1966 decision to label part of government off

On the Prelude to 14th February Uprising

The book explores the contentious politics of Bahrain, and charts the way in which a dynamic culture of street protest, a strong moral belief in legitimate democratic demands and creative forms of resistance continue to hamper the efforts of the ruling elite to rebrand itself as a liberal, modernising monarchy. Drawing on powerful testimonies, interviews and conversations from those involved, this

Photochemical reactions in biological light perception and regulation

Many photochemical reactions involved in the sensing of and regulation by light and ultraviolet radiation by organisms consist of cis-trans (and trans-cis) isomerisations. This chapter starts with a description of these, and then goes on to the blue-light receptors crypto-chrome and phototropin, which use other chemical mechanisms, and concludes with a discus-sion of ultraviolet-B receptors.

Parabolic synthesis methodology implemented on the sine function

This paper introduces a parabolic synthesis methodology for implementation of approximations of unary functions like trigonometric functions and logarithms, which are specialized for efficient hardware mapped VLSI design. The advantages with the methodology are, short critical path, fast computation and high throughput enabled by a high degree of architectural parallelism. The feasibility of the m

The role of B cells and Th2 cytokines in physiological and pathological inflammation

Popular Abstract in Swedish Vårt immunförsvar har utvecklats genom evolutionen för att kunna motstå infektioner från diverse mikrober (parasiter, bakterier, virus). Kroppen svarar då med en inflammationsrespons för att kunna bekämpa infektionen. Immunsvaret kan delas upp i det icke specifika immunsvaret, bestående av bl.a. fagocyterande celler samt det specifika immunsvaret, bestående av sk T och The CD4+ T cells have an important role in inflammation. Based on the local cytokine milieu, these cells can differentiate into either a Th1 population promoting cellular immunity or Th2 population involved in humoral immunity. Th2 cells produce the anti-inflammatory cytokines IL-4 and IL-10, which might have a protective role in autoimmune diseases like rheumatoid arthritis (RA) and multiple scle

Tendencies of Swedish word accent production by L2-learners with tonal and non-tonal L1

A comparison between second language learners of Swedish, some of whom have an L1 with lexical tones, while the others do not, and their ability to produce adequate tonal word accents in Swedish is presented. The L1s in question are Farsi, Somali, Vietnamese and Thai. There is no clear evidence that it is easier to learn the correct Swedish word accent patterns and their correct application for sp

Studies of molecular events during peripheral B cell differentiation

Popular Abstract in Swedish Immunsystemet skyddar oss mot de patogener (t ex bakterier eller virus) som vi dagligen utsätts för. Det består av flera olika samtidigt verkande system. De enklare består av vår hud och de olika slemhinnor som finns till exempel i halsen och i tarmsystemet. Vidare finns det olika typer av celler och blodproteiner som kan skydda oss mot många infektioner. Det mest utvecThis thesis focuses on molecular changes occuring during terminal B cell differentiation as well as on somatic hypermutation and the generation and maintenance of B cell memory. During T cell dependent immune responses the average affinity for the eliciting antigen increases with time. This affinity maturation is generated by somatic hypermutation and selection for B cells carrying a high-affinty

On the use of Titration Calorimetry to Study the Association of Surfactants in Aqueous Solutions

Isothermal titration calorimetry is increasingly becoming a common tool for the investigation of surfactant association processes. This can be associated with the development of new, sensitive and easy-to-operate commercial equipment, allied with the advantage of producing simultaneous information on the main thermodynamic parameters associated with the process under investigation. However, a sign

Uneven distribution of repetitive trinucleotide motifs in human immunoglobulin heavy variable genes

Insertions and deletions of entire codons have recently been discovered as a mechanism by which B cells, in addition to conventional base substitution, evolve the antibodies produced by their immunoglobulin genes. These events frequently seem to involve repetitive sequence motifs in the antibody-encoding genes, and it has been suggested that they occur through polymerase slippage. In order to bett

S100A9 as a pharmacological target molecule in inflammation and cancer.

Upon tissue injury and infection both stressed and dying cells can release proteins that normally reside inside the cells. Some of the released proteins become ligands of various cell surface receptors expressed by local cells and such proteins are denoted damage associated molecular patterns (DAMPs). Binding of some DAMPs to certain cell surface receptors induces signals emanating in the producti