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No effect of femoral canal jet-lavage on the stability of cementless stems in primary hip arthroplasty : a randomised RSA study with 6 years follow-up

Introduction: In contrast to cemented hip prostheses, the effect of washing the bone bed with jet-lavage prior to insertion of cementless stem components in primary hip arthroplasty (THA) is unclear. Jet-lavage potentially decreases the risk of fat embolisation during rasping and stem insertion and might help in avoiding bacterial contamination. An earlier animal study has shown less debris and be

Automatic exchange of information and cross border flows of personal data

International cooperation between national tax authorities through exchange of information is becoming even more important than it was before in combating tax evasion. In this chapter, the implementation of automatic exchange of information is discussed with a focus on cross border flows of personal data. First, we discuss the legal framework for the ex-change of information. Article 26 of the OEC

Where and how do you buy medicines? A social and cultural study of attitudes towards buying medicines online and abroad among Swedish public

We start our presentation with a brief overview of the literature written about SF medical products in the social and cultural sciences. In September 2015, we broadly reviewed literature about the phenomenon of SF medical products, and identified research gaps regarding social, cultural and ethical aspects. Studies, presented below, are two pilot studies aimed to fill some of the gaps. In May 2018

N-cadherin is dispensable for pancreas development but required for beta-cell granule turnover.

The cadherin family of cell adhesion molecules mediates adhesive interactions that are required for the formation and maintenance of tissues. Previously, we demonstrated that N-cadherin, which is required for numerous morphogenetic processes, is expressed in the pancreatic epithelium at E9.5, but later becomes restricted to endocrine aggregates in mice. To study the role of N-cadherin during pancr

How to model solvent effects on molecular properties using quantum chemistry? Insights from polarizable discrete or continuum solvation models

We present a comparative study of solvent effects on the N-15 NMR shielding constants and the lowest electronic excitation energy (n -> pi*) in the three diazines (pyrazine, pyrimidine, and pyridazine) in aqueous solution. This solvent is modeled using either a polarizable continuum model (PCM) or a discrete polarizable model (DPM). We analyze the results obtained with the two models in terms of d

pi* -> n fluorescence transition in formaldehyde in aqueous solution: A combined quantum chemical statistical mechanical study

The solvent shift to the fluorescence transition pi* -> n in formaldehyde in aqueous Solution is theoretically analyzed. The solvent model has explicit representation of the solvent and uses the complete active space state interaction (CASSI) method to obtain a description of the wave function of the solute similar to what the complete active space self-consistent-field (CASSCF) method would give.

Noninvasive functional optical spectroscopy of human breast tissue

Near infrared diffuse optical spectroscopy and diffuse optical imaging are promising methods that eventually may enhance or replace existing technologies for breast cancer screening and diagnosis. These techniques are based on highly sensitive, quantitative measurements of optical and functional contrast between healthy and diseased tissue. In this study, we examine whether changes in breast physi

Expression of CD137 (4-1BB) on Human Follicular Dendritic Cells

Follicular dendritic cells (FDCs) are the antigen (Ag)-trapping accessory cells of the germinal centres (GCs), essential for the development of humoral immune responses and memory. FDCs reside in the microenvironment of secondary lymphoid tissue where Ag-activated B cells expand, and undergo isotype switching and affinity maturation prior to becoming memory B cells. In addition to delivering Ag, F

Both Low and High Serum IGF-I Levels Associate with Cancer Mortality in Older Men.

Background: Although recent population-based studies suggest a U-shaped relationship between serum IGF-I concentration and all-cause mortality, the distribution of death causes underlying this association remains unclear. We hypothesized that high IGF-I levels associate with increased cancer mortality, whereas low IGF-I levels associate with increased cardiovascular disease (CVD) mortality. Metho

Identifying factors that may impact the adoption and use of a social science collaboratory: a synthesis of previous research

Introduction. This paper examines and synthesizes previous research in scientific collaboration, scholarly communication, scientific collaboratories, scientific disciplines, invisible colleges and virtual communities to identify factors that may impact the design, adoption and use of a collaboratory within librarianship and information science. Results. A taxonomy of factors that appear to impact

The 'We' that bear the burden of the European Dilemma - Can 'We' together?

This contribution provides interdisciplinary analysis of expressions of austerity-policies. It is argued that expressions of austerity-policies are meaningful if and only if intended addressees’ psychological states are adequately attuned and conceptual preconditions for implementation met. Furthermore, it is argued that if addressees are suitably psychologically attuned and preconditions met, uti

Incretin Hormone and Insulin Responses to Oral Versus Intravenous Lipid Administration in Humans.

Context: The incretin effect is responsible for the higher insulin response to oral glucose than to iv glucose at matching glucose levels. It is not known whether this effect is restricted to glucose only. Objective: The aim of the study was to examine whether insulin and incretin hormone responses are higher after oral vs. iv challenge of a lipid emulsion with matching triglyceride levels in huma