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The Effect of Postadded Ethylene Glycol Surfactants on DNA-Cationic Surfactant/Water Mesophases.

The addition of amphiphiles grafted with polyethylene glycol units to constructs of DNA-amphiphiles is of most relevance for applications demanding colloidal stability. In this work, we study the self-assembly behavior of a true ternary mixture comprising (i) an electroneutral complex of DNA and a cationic surfactant (dodecyltrimethylammonium, DTA), (ii) water, and (iii) nonionic surfactant (dodec

The history of scatter hoarding studies.

In this review, I will present an overview of the development of the field of scatter hoarding studies. Scatter hoarding is a conspicuous behaviour and it has been observed by humans for a long time. Apart from an exceptional experimental study already published in 1720, it started with observational field studies of scatter hoarding birds in the 1940s. Driven by a general interest in birds, sever

LL-37-induced host cell cytotoxicity depends on cellular expression of the globular C1q receptor (p33).

The human host-defense peptide LL-37 not only displays antimicrobial activity but also immune modulating properties that trigger intracellular signaling events in host cells. Since the cytolytic activity of high LL-37 concentrations affects cell viability, the function of LL-37 requires tight regulation. Eukaryotic cells therefore benefit from protective measures to prevent harmful effects of LL-3

Assessment and analysis of housing accessibility: adapting the environmental component of the housing enabler to United States applications.

The home environment is a primary context for daily activities, especially among older adults and persons with disabilities. Functional and age-related decline can generate problems in relation to certain environmental features, necessitating modifications or other provisions of support. The determination of appropriate home interventions is best served using a person–environment (P–E) fit approac

The GARD assay for assessment of chemical skin sensitizers.

Allergic contact dermatitis is a skin disease caused by an immunologic reaction to low molecular weight compounds, so called haptens. These substances are commonly present in products used by humans in daily life, such as in cosmetics and fragrances, as well as within chemical industry and in pharmaceuticals. The frequent usage of these compounds in different applications has led to increasing inc

Mediatization at the Margins : Cosmopolitanism, Network Capital, and Spatial Transformation in Rural Sweden

The significance of mediatization in countryside settings is an under-researched topic in media studies. In this paper, based on qualitative fieldwork carried out in two rural areas in Sweden, we study how mediatization integrates the prospects of cosmopolitan social change. The current phase of the mediatization process, which imposes a more dynamic register of networked communication, nourishes

Unintelligent Design: A Discussion of Steve Fuller's Dissent over Descent

In this discussion, Steve Fuller's book Dissent over Descent is criticized mainly because he draws conclusions from wishful thinking and uses ancient and medieval scientists as well as theologians in his efforts to invalidate the theory of evolution. He is also criticized for drawing universal conclusions from a Eurocentric version of history. If science and technology studies is to regain its rep

DNA interaction with catanionic vesicles

DNA-cationic liposome complexes as possible vehicles for gene delivery is currently an important issue. In this work, the interaction between DNA and thermodynamically stable, spontaneously formed, catanionic vesicles with a net positive charge is studied. A phase map was drawn for the aqueous system of DNA and positively charged vesicles, composed of CTAB (cetyltrimethylammonium bromide) and SOS

Investigation of the segregative phase separation induced by addition of polystyrene to AOT oil-continuous microemulsions

The effect of different molecular weight polystyrenes (PS) on the phase behavior of sodium 1,4-bis(2-ethylhexyl) sulfosuccinate (AOT)/water/cyclohexane oil-continuous microemulsions was investigated. The surfactant-covered water droplets were treated as a pseudocomponent in the mixture, and ternary polymer/droplet/oil phase diagrams were established as a function of microemulsion droplet radius (2

Complex formation in solutions of oppositely charged polyelectrolytes at different polyion compositions and salt content

The formation of complexes in solutions containing positively charged polyions (polycations) and a variable amount of negatively charged polyions (polyanions) has been investigated by Monte Carlo simulations. The polyions were described as flexible chains of charged hard spheres interacting through a screened Coulomb potential. The systems were analyzed in terms of cluster compositions, structure

Mixing oil and water by a DNA-based surfactant

The self-assembly behavior of a cationic surfactant (dodecyltrimethylammonium) with DNA as counterion in mixtures of water and decanol was investigated. The phase diagram was established and the different regions of the phase diagram characterized with respect to microstructure by H-2 NMR (D2O), small-angle X-ray scattering (SAXS), and other techniques. The DNA-cationic surfactant aggregate is vir

Characterization of the protein-synthesis dependent adaptive acid tolerance response in Lactobacillus acidophilus

Exposure of L. acidophilus CRL 639 cells to sublethal adaptive acid conditions (pH 5.0 for 60 min) was found to confer protection against subsequent exposure to lethal pH (pH 3.0). Adaptation, which only occurred in complex media, was dependent on de novo protein synthesis and was inhibited by amino acid analogues. There was no modification in the protein synthesis rate during adaptation, but the

Family structure in the Siberian Jay as revealed by microsatellite analyses

The Siberian Jay (Perisoreus infaustus) lives in resident, territorial family groups outside the breeding season, but does not breed cooperatively. Thereby it offers an opportunity to study the evolution of territorial group living, without confounding effects of reproductive cooperation. During a long-term study in Finland 1974-2000, we observed Siberian Jay group composition in autumn. Using mic

Immune responses to bile-tolerant Helicobacter species in patients with chronic liver diseases, a randomized population group, and healthy blood donors

Bile-tolerant Helicobacter species such as Helicobacter pullorum, Helicobacter bilis, and Helicobacter hepaticus are associated with hepatic disorders in animals and may be involved in the pathogenesis of chronic liver diseases (CLD) in humans. Antibody responses to cell surface proteins of H. pullorum, H. bilis, and H. hepaticus in serum samples from patients with CLD, a randomized population gro

Transepithelial neutrophil migration is CXCR1 dependent in vitro and is defective in IL-8 receptor knockout mice

Neutrophil migration across infected mucosal surfaces is chemokine dependent, but the role of chemokine receptors has not been investigated. In this study, chemokine receptors were shown to be expressed by epithelial cells lining the urinary tract, and to play an essential role for neutrophil migration across the mucosal barrier. Uroepithelial CXCR1 and CXCR2 expression was detected in human urina