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The Statistical Distribution of Irrationality

This paper investigates whether the shape of a probability distribution of a given problem has any predictable effect on the shape of the distribution of people's associated irrational choices. Focus is especially on the skewness of distributions. Based on previous research in psychology and behavioral economics, a theory of the causes of skewness of choice distributions is presented. Hypothes

Interna motverkansåtgärder i förhållande till skatteavtalen

I syfte att undvika dubbelbeskattning och på så sätt skapa goda för-utsättningar för tillväxt på den globala marknaden, väljer många stater att ingå skatteavtal. En baksida med skatteavtalen är att de i vissa situationer resulterar i dubbel icke-beskattning. Vissa inkomster beskattas med andra ord inte alls, tack vare skatteavtalet. I syfte att förhindra dessa situationer, väljer många stater att In order to avoid double taxation and thus create good conditions for the growth on the global market, many states choose to conclude tax treaties. However, the downside of tax treaties is that they in certain cases results in double non-taxation. Some income is in other words not taxed at all, due to the tax treaty. To prevent these situations, many states legislate against tax evasion and tax av

Concordance of Tumor Differentiation Among Brothers with Prostate Cancer

Background: Genetic factors seem to be of greater importance in prostate cancer than in other forms of cancer. Studies have suggested familial concordance in survival, but the extent to which that is due to tumor characteristics is not known. Objective: We hypothesized that a brother of an index case with prostate cancer is at particularly increased risk of prostate cancer with the same tumor diff

Blood pressure in relation to the incidence of cerebral infarction and intracerebral Hemorrhage - Hypertensive hemorrhage: Debated nomenclature is still relevant

Background and Purpose - Data regarding the association between blood pressure level and incidence of stroke subtype, especially primary intracerebral hemorrhage (PICH) subtypes, is sparse. This population- based study explored the relationship between blood pressure and the incidence of cerebral infarction, and PICH, with lobar and nonlobar location. Methods - Risk factors were assessed in 27 702

Tumour necrosis factor blockers do not increase overall tumour risk in patients with rheumatoid arthritis, but may be associated with an increased risk of lymphomas

Objective: To determine whether TNF blockers increase tumour risk in patients with RA. Material and methods: The South Swedish Arthritis Treatment Group register (SSATG) comprises over 90% of anti-TNF treated patients with RA in the area. 757 patients treated with etanercept or infliximab included between 1 February 1999 and 31 December 2002 were identified. 800 patients with conventional antirheu

Epidemiology of fractures in Iceland and secular trends in major osteoporotic fractures 1989-2008

The incidence of the most common fracture types in Iceland is reported based on individual data from the Reykjavik Study 1967-2008. Time trend is reported for the major osteoporotic fractures (MOS) 1989-2008. This study aims to assess the incidence of all fractures in Iceland, with emphasis on the rate of hip fractures, and compare the incidence with other populations as well as examine the secula

From disease to genes in animal models of rheumatoid arthritis and multiple sclerosis

Rheumatoid arthritis (RA) and multiple sclerosis (MS) are complex inflammatory autoimmune diseases. The aetiology is largely unknown but the risk of developing disease is dependent on both genetic and environmental factors. Extensive efforts have been done to identify the underlying genes in order to understand the molecular mechanisms of the diseases. Until recently, only a few genes have been qu

Long-term patient survival in ANCA-associated vasculitis

Background Wegener's granulomatosis and microscopic polyangiitis are antineutrophil cytoplasm antibodies (ANCA)-associated vasculitides with significant morbidity and mortality. The long-term survival of patients with ANCA associated vasculitis treated with current regimens is uncertain. Objective To describe the long-term patient survival and possible prognostic factors at presentation in an inte

Anti-tumour necrosis factor therapy in rheumatoid arthritis and risk of malignant lymphomas:relative risks and time-trends in the Swedish Biologics Register

Background: Tumour necrosis factor (TNF) antagonists have proved effective as treatment against rheumatoid arthritis ( RA), but the unresolved issue of whether the use of anti-TNF therapy increases the already elevated risk of lymphoma in RA remains a concern. Methods: Using the Swedish Biologics Register (ARTIS), the Swedish Cancer Register, pre-existing RA cohorts and cross-linkage with other na

Causes and risk factors for death in systemic sclerosis: a study from the EULAR Scleroderma Trials and Research (EUSTAR) database

Objectives To determine the causes and predictors of mortality in systemic sclerosis (SSc). Methods Patients with SSc (n=5860) fulfilling the American College of Rheumatology criteria and prospectively followed in the EULAR Scleroderma Trials and Research (EUSTAR) cohort were analysed. EUSTAR centres completed a structured questionnaire on cause of death and comorbidities. Kaplan-Meier and Cox pro

Association between dietary fiber intake and risk of incident aortic stenosis

Background and aims: Although aortic stenosis is the most common valvular heart disease requiring intervention in Europe, the role that diet plays in development of the disease is largely unknown. The pathophysiology of aortic stenosis is however similar to other cardiovascular diseases that fiber intake has been associated with. The aim of this study was consequently to investigate the associatio

Efficacy and tolerability of tropisetron in comparison with a combination of tropisetron and dexamethasone in the control of nausea and vomiting induced by cisplatin-containing chemotherapy

In a double-blind, randomised, multicentre study, the efficacy and tolerability of tropisetron and a combination of tropisetron and dexamethasone were compared for the control of nausea and vomiting induced by cisplatin in patients previously not entirely protected by tropisetron monotherapy. In all, 160 women with gynaecological cancers were studied during two consecutive courses of cisplatin-con

Healthy diet and fiber intake are associated with decreased risk of incident symptomatic peripheral artery disease – A prospective cohort study

Peripheral artery disease (PAD) is caused by atherosclerosis and associated with an increased risk of leg amputation, cardiovascular disease, and death. A healthy diet has been shown to reduce the risk of cardiovascular events, but relationships between diet, fiber intake, and incidence of PAD are virtually unknown. The aim was to investigate the long-term impact of diet on the development of PAD

Different boreal terrestrial DOC sources show different δ13C signatures: implications for tracing labile doc across the land-water interface

The stable carbon isotope ratio (δ13C) is a key tool in tracing the source of carbon within and across ecosystems. In isotope mixing models dissolved organic carbon (DOC) from terrestrial sources is often assigned a fixed δ13C of roughly -28‰ to -27‰ in C3 plant-dominated areas. However, the claim of a uniform δ13C distribution for terrestrial DOC sources of different reactivity has seldom been te

Familial risk of cancer : data for clinical counseling and cancer genetics

Familial risks for cancer are important for clinical counseling and understanding cancer etiology. Medically verified data on familial risks have not been available for all types of cancer. The nationwide Swedish Family-Cancer Database includes all Swedes born in 1932 and later (0-to 68-year-old offspring) with their parents, totaling over 10.2 million individuals. Cancer cases were retrieved from

Motion Generators Combined with Behavior Trees: A Novel Approach to Skill Modelling

Task level programming based on skills has often been proposed as a mean to decrease programming complexity of industrial robots. Several models are based on encapsulating complex motions into self-contained primitive blocks. A semantic skill is then defined as a deterministic sequence of these primitives. A major limitation is that existing frameworks do not support the coordination of concurrentTask level programming based on skills has often been proposed as a mean to decrease programming complexity of industrial robots. Several models are based on encapsulating complex motions into self-contained primitive blocks. A semantic skill is then defined as a deterministic sequence of these primitives. A major limitation is that existing frameworks do not support the coordination of concurrent

Protease Inhibitors or NNRTIs as First-Line HIV-1 Treatment in West Africa (PIONA) : A Randomized Controlled Trial

BACKGROUND: Nonnucleoside reverse transcriptase inhibitors (NNRTIs) are recommended as part of first-line treatment for HIV-1 in Africa. However, NNRTI-based regimens are more prone to resistance development than protease inhibitors (PIs) in a context in which drug interruptions are frequent. The aim of this study was to compare the efficacy and tolerability of NNRTIs with PIs in HIV-1-infected pa

Multi-omic biomarker identification and validation for diagnosing warzone-related post-traumatic stress disorder

Post-traumatic stress disorder (PTSD) impacts many veterans and active duty soldiers, but diagnosis can be problematic due to biases in self-disclosure of symptoms, stigma within military populations, and limitations identifying those at risk. Prior studies suggest that PTSD may be a systemic illness, affecting not just the brain, but the entire body. Therefore, disease signals likely span multipl

Who should record surgical complications? Results from a third-party assessment of complications after radical cystectomy

Objective: In Sweden complications after radical cystectomy have been reported to the nationwide population-based Swedish Cystectomy Registry since 2011. Here, validation of the reporting was assessed in two healthcare regions. Materials and methods: Complications were ascertained from patient records by a third party not involved in the care delivered to 429 randomly selected patients from 949 wh