Search results

BACKGROUND: Autonomic disorders of the cardiovascular system, such as orthostatic hypotension and elevated resting heart rate, predict mortality and cardiovascular events in the population. Low-energy-fractures constitute a substantial clinical problem that may represent an additional risk related to such autonomic dysfunction.AIMS: To test the association between orthostatic hypotension, resting

Measures of muscle mass, strength, and function predict risk of incident fractures, but it is not known whether this risk information is additive to that from FRAX (fracture risk assessment tool) probability. In the Osteoporotic Fractures in Men (MrOS) Study cohorts (Sweden, Hong Kong, United States), we investigated whether measures of physical performance/appendicular lean mass (ALM) by DXA pred

Background: Sweden has closed all institutions and imposed legislation to ensure service and support for individuals with intellectual disability (ID). Understanding mortality among older individuals with ID is essential to inform development of health promotion and disease control strategies. We investigated patterns and risk of mortality among older adults with ID in Sweden. Methods: This retros

OBJECTIVES: The predictive ability of the STarT Back Tool (SBT) has not yet been examined among acute/subacute back and/or neck pain in a primary care setting in respect to health-related quality of life (HRQoL) and work ability outcomes. The aim of this study was to evaluate the SBT's predictive validity for HRQoL and work ability outcomes at long-term follow-up in a population with acute/subacut

Abstract: Cardiovascular diseases and diabetes mellitus are closely linked by sharing common risk factors, such as obesity, insulin resistance, hypertension and dyslipidaemia. These intermediate risk factors are affected by the joint effects of environment and genetics. Although a multitude of studies aimed to disentangle the effects of gene-environment interactions, many of the published gene-en

BACKGROUND: Identification of risk factors for rapid joint destruction in early rheumatoid arthritis (RA) can be helpful for optimizing treatment, and improving our understanding of destructive arthritis and its mechanisms. The objective of this study was to investigate the relationship between early RA patient characteristics and subsequent rapid radiographic progression (RRP).METHODS: An incepti

PurposeThe paper analyzes power effects of the strategy discourse to create a more profound understanding of how strategy seen as a discourse constitutes certain identities and practices among communication practitioners. The following two research questions has been posed to concretize the overall aim of the study: 1) What has the strategy discourse meant for practitioners understanding of themse

The holotype (KUVP 1301) of Styxosaurus snowii—one of the earliest described elasmosaurid plesiosaurians—consists of a well-preserved cranium, mandible and articulated sequence of anterior–mid-series cervical vertebrae found in the lowermost Campanian strata of the Smoky Hill Chalk Member in the Niobrara Formation of Kansas, USA. This particular specimen has proven important for recent phylogenies

Background Clinical health promotion significantly improves treatment outcomes in hospitals and health services on both long and short term. Therefore, the World Health Organization (WHO) and the International Network of Health Promoting Hospitals & Health Services (HPH) developed and validated three easy-to-use tools that have been implemented by many national, regional and local health care

Peatlands store substantial amounts of carbon and are vulnerable to climate change. We present a modified version of the Organising Carbon and Hydrology In Dynamic Ecosystems (ORCHIDEE) land surface model for simulating the hydrology, surface energy, and CO2 fluxes of peatlands on daily to annual timescales. The model includes a separate soil tile in each 0.5° grid cell, defined from a global peat

Objective: Retrograde open mesenteric stenting (ROMS) through laparotomy was introduced as an alternative to surgical bypass in patients with acute mesenteric ischemia (AMI). The purpose of this study was to evaluate the indications and outcomes of ROMS for treatment of AMI and chronic mesenteric ischemia. Methods: We reviewed the clinical data and outcomes of all consecutive patients treated by R

Context. Pismis 18 is a moderately populated, intermediate-Age open cluster located within the solar circle at a Galactocentric distance of about seven kpc. Few open clusters have been studied in detail in the inner disc region before the Gaia-ESO Survey. Aims. New data from the Gaia-ESO Survey allowed us to conduct an extended radial velocity membership study as well as spectroscopic metallicity

Background: In addition to the established association between general obesity and breast cancer risk, central obesity and circulating fasting insulin and glucose have been linked to the development of this common malignancy. Findings from previous studies, however, have been inconsistent, and the nature of the associations is unclear.Methods: We conducted Mendelian randomization analyses to evalu

We study the solvability for a system of pseudodifferential operators. We will assume that the systems is of principal type, i.e., the principal symbol vanishes of first order on the kernel, and that the eigenvalue close to zero has constant multiplicity. We prove that local solvability is to condition (PSI) on the eigenvalues as in the scalar case. This condition rules out any sign changes from -

BACKGROUND: Glibenclamide (Gb) may provoke long-lasting hypoglycaemic reactions, and one of the known risk factors is impaired renal function. We have demonstrated Gb to have a terminal elimination half-life of 15 h, and the main metabolites have a hypoglycaemic effect. With few exceptions, detailed studies on second generation sulphonylureas in diabetics with impaired renal function are lacking.

BACKGROUND: Patients on dialysis who have an acute myocardial infarction (AMI) have an exceedingly poor prognosis, but it is unknown to what extent guideline-recommended interventions and treatments are used and to which benefit. We aimed to assess temporal changes in the use of treatments and survival rates in dialysis patients with an AMI. METHODS AND RESULTS: All consecutive AMI cases from 1996

Background and ObjectivesIdentifying a clinically meaningful change in cognitive test score is essential when using cognition as an outcome in clinical trials. This is especially relevant because clinical trials increasingly feature novel composites of cognitive tests. Our primary objective was to establish minimal clinically important differences (MCIDs) for commonly used cognitive tests, using a