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Interim Report on Gribshunden (1495) Excavations: 2019–2021

We present an interim archaeological report on the ship- wreck of the Danish-Norwegian flagship Gribshunden. Built in 1485, extensively employed by King Hans as his floating castle, and ultimately lost in June 1495 en route to Kalmar, the ship carried people and material selected to further the political goal of re-unifying the Nordic region. Three field campaigns led by Lund University and Blekin

Enhanced left-finger deftness following dominant upper- and lower-limb amputation

BACKGROUND: After amputation, the sensorimotor cortex reorganizes, and these alterations might influence motor functions of the remaining extremities.OBJECTIVE: The authors examined how amputation of the dominant or nondominant upper or lower extremity alters deftness in the intact limbs.METHODS: The participants were 32 unilateral upper- or lower-extremity amputees and 6 controls. Upper-extremity

Bringing Death to Life: The Personifications of Death in Zusak's The Book Thief, Moore's A Dirty Job and Pendle's Death: A Life

This essay examines the personifications of Death in Markus Zusak’s The Book Thief (2005), Christopher Moore’s A Dirty Job (2006) and George Pendle’s Death: A Life (2008). The personifications are analysed in terms of gender, anthropomorphism, (im)mortality, agency in conceptual death and attitude towards their occupation as Death. The personifications are also compared to previous portrayals in r

The Triangle of Mistrust: A Utility's Struggle to Engage Effectively in the Informal Settlements of Nairobi

“Water is life”. During the past decade this phrase has been used repeatedly to emphasize the importance of a number of issues surrounding water services provision including, supply, distribution, governance and political will. This research seeks to investigate the Nairobi City Water and Sewerage Company (NCWSC), a water utility in Kenya, which faces the monumental task of providing water and san

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NYTT FRÅN SACO-S SLU Innehåll: • Julhälsning • Information • Lästips • Lönerevision 2025 • Webbinarier • SACO-S SLU styrelse (In English further below) Julhälsning År 2025 har varit intensivt med många förändringar och ärenden rörande avtal, ny arbetsmiljöorganisation, omorganisationer och verksamhetsförändringar, arbetsmiljöärenden och medlemsstöd. Vi är glada över att vi kunnat bjuda in våra med

https://www.saco.se/globalassets/lokala-akademikerforeningar/statlig/slu/nyhetsbrev/nyhetsbrev_2025-5.pdf - 2026-05-05

IgG glycan hydrolysis by a bacterial enzyme as a therapy against autoimmune conditions.

EndoS from Streptococcus pyogenes efficiently hydrolyzes the functionally important and conserved N-linked glycan of IgG in human blood. Repeated i.v. administration of EndoS in rabbits completely hydrolyzes the glycans of the whole IgG pool, despite the generation of anti-EndoS antibodies. EndoS administration had no apparent effects on the health of the animals. EndoS hydrolysis of the IgG glyca

Prevention and Management of Bleeding Episodes in Children with Hemophilia

Regular prophylactic treatment with factor VIII (FVIII) and factor IX (FIX) concentrates in hemophilia A and B, respectively, is introduced in early infancy and has resulted in dramatic improvement of the conditions. Recombinant FVIII and FIX concentrates have been available for > 25 years and have been modified and refined through the years; however, unfortunately frequent intravenous administrat

Induction of platelet thrombi by bacteria and antibodies.

We have characterized 2 distinct mechanisms through which infectious agents may promote platelet adhesion and thrombus formation in flowing blood, thus contributing to the progression of disease. In one case, the process initiates when the integrin alpha(IIb)beta(3) mediates platelet arrest onto immobilized bacterial constituents that have bound plasma fibrinogen. If blood contains antibodies agai

Engineering Af1521 improves ADP-ribose binding and identification of ADP-ribosylated proteins

Protein ADP-ribosylation is a reversible post-translational modification that regulates important cellular functions. The identification of modified proteins has proven challenging and has mainly been achieved via enrichment methodologies. Random mutagenesis was used here to develop an engineered Af1521 ADP-ribose binding macro domain protein with 1000-fold increased affinity towards ADP-ribose. T

Countercurrent distribution of lymphocytes from human peripheral blood in an aqueous two-phase system. : II. Separation into subsets of lymphocytes with distinctive functions

Lymphocytes from human peripheral blood were separated by Countercurrent distribution (CCD) in a charged aqueous two-phase system composed of Dextran T 500 and polyethylene glycol 6000. Maximal responses to the T-cell mitogens phytohemagglutinin and concanavalin A were detected in a part of the distribution corresponding to the area where the highest percentage of E rosetting cells were seen. Anti

Group B Streptococcus suppression of phagocyte functions by protein-mediated engagement of human Siglec-5

Group B Streptococcus (GBS) is a leading cause of invasive bacterial infections in human newborns. A key GBS virulence factor is its capsular polysaccharide (CPS), displaying terminal sialic acid (Sia) residues which block deposition and activation of complement on the bacterial surface. We recently demonstrated that GBS Sia can bind human CD33-related Sia-recognizing immunoglobulin (Ig) superfami