Previously we reported the presence of anti-idiotypic antibodies (anti-Id) specific to autoantibodies against GAD65 (GAD65Ab) in healthy individuals while the activity of anti-Id directed to GAD65Ab in T1D patients was significantly lower. These anti-Id recognize the antigen binding site of GAD65Ab, thus preventing their binding to GAD65. Here we characterized the IgG subclass profile of these ant

A set of successively more accurate self-consistent equations for the one-electron Green's function have been derived. They correspond to an expansion in a screened potential rather than the bare Coulomb potential. The first equation is adequate for many purposes. Each equation follows from the demand that a corresponding expression for the total energy be stationary with respect to variations in

It has recently been reported that women treated with low molecular weight heparin (LMWH) during pregnancy had 3 h shorter duration of delivery. The aim of the present study was to evaluate whether LMWH (dalteparin) affects labour. From January 1996 to December 2005, 217 consecutive pregnancies, out of 34 216 newborn (prevalence 0.6%) that were given thromboprophylaxis with dalteparin (usually 5,0

Seven Campylobacter jejuni strains were characterised by a lectin typing assay. The typing system was based on a quartz crystal microbalance technique (QCM) with four commercially available lectins (wheat germ agglutinin, Maackia amurensis lectin, Lens culinaris agglutinin, and Concanavalin A), which were chosen for their differing carbohydrate specificities. Initially, the gold surfaces of the qu

We report on measurements of radiative lifetimes in singly ionized iron of six 3d(6)4p levels between 61 512 and 64 041 cm(-1),using time resolved laser-induced fluorescence. Absolute oscillator strengths of 18 Fe II lines in the wavelength range from 2350 to 2800 Angstrom have been obtained by measuring branching fractions for the lines from two Fe II levels with a Fourier-transform spectrometer.

Objective: Primary adrenal insufficiency [Addison's disease (AD)] is rare, and systematic studies are few, mostly conducted on small patient samples. We aimed to determine the clinical, immunological, and genetic features of a national registry-based cohort. Design: Patients with AD identified through a nationwide search of diagnosis registries were invited to participate in a survey of clinical f

BACKGROUND: Cigarette smoking enhances the risk of stroke. However, the underlying molecular mechanisms are largely unknown. The present study established an in vivo rat secondhand cigarette smoking (SHS) model and examined the hypothesis that SHS upregulates endothelin receptors with increased cerebrovascular contraction via the Raf/extracellular signal-regulated kinase (ERK)/mitogen-activated pr

The combination of features from the public and private sectors in jointly owned companies imposes challenges to the governance and control mechanisms of these organisations, which have been criticised for lacking accountability. Where there is fragmented ownership, the interests of different owners need to be coordinated. The aim of this article is to consider how such companies can be governed i

Rapporten behandlar ett projekt som utifrån samverkan undersökte möjligheterna att använda människors minnen och historia som utgångspunkt för att utveckla en plats, specifikt det hamnområde som omvandlas till området Oceanhamnen i Helsingborg genom utvecklingsprojektet H+. Människor med anknytning till hamnen intervjuades, arkivmaterial och annat samlades in. Materialet sammanställdes och blev ut

Background: Subjective well-being refers to the extent to which a person believes or feels that her life is going well. It is considered as one of the best available proxies for a broader, more canonical form of well-being. For over 30 years, one important distinction in the conceptualization of subjective well-being is the contrast between more affective evaluations of biological emotional reacti

Within the field of tourism information search behaviour, this research aims at exploring the proposed concept of ‘planned serendipity’ and its connection with smartphone use for tourism information search. Although studies on smartphone and tourism have flourished in the past few years, research on information needs and how these needs exist in relation to smartphones is lacking. Moreover, there

Pathogenic sequence variants (PSV) in BRCA1 or BRCA2 (BRCA1/2) are associated with increased risk and severity of prostate cancer. We evaluated whether PSVs in BRCA1/2 were associated with risk of overall prostate cancer or high grade (Gleason 8+) prostate cancer using an international sample of 65 BRCA1 and 171 BRCA2 male PSV carriers with prostate cancer, and 3,388 BRCA1 and 2,880 BRCA2 male PSV

Background of the study One of the main challenges in tourism research is to find effective methodologies to capture the salient moments that make a tourist experience memorable (Cary, 2004; Tussyadiah, 2014). A gap exists between the tourist experience – which happens at a destination, during the time of the trip – and the recollection of it during the study – which often happens days, weeks or m

We analyse the validity of a commonly used identification between structures of the virtual photon γ∗→ QQ¯ and vector meson V→ QQ¯ transitions. In the existing studies of S-wave vector-meson photoproduction in the literature, such an identification is typically performed in the light-front (LF) frame while the radial component of the meson wave function is rather postulated than computed from the

In this work, we present a thorough analysis of ηc(1S, 2S) quarkonia hadroproduction in k⊥-factorisation in the framework of the light-front potential approach for the quarkonium wave function. The off-shell matrix elements for the g*g*ηc(1S, 2S) vertices are derived. We discuss the importance of taking into account the gluon virtualities. We present the transverse momentum distributions of ηc for

Travel guidebooks are both travel information channels and objects of consumption. In contemporary tourism, Information and Communication Technologies (ICT) make information abundant and mostly free of charge. Therefore, as tourists still buy them, there must be something that makes guidebooks a valuable object. This research aims at understanding the value of travel guidebooks in the digital age.

Amyloid beta peptides (Aβ) proteins play a key role in vascular pathology in Alzheimer’s Disease (AD) including impairment of the blood–brain barrier and aberrant angiogenesis. Although previous work has demonstrated a pro-angiogenic role of Aβ, the exact mechanisms by which amyloid precursor protein (APP) processing and endothelial angiogenic signalling cascades interact in AD remain a largely un