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Arsenic, an established carcinogen and toxicant, occurs in drinking water and food and affects millions of people worldwide. Arsenic appears to interfere with gene expression through epigenetic processes, such as DNA methylation and post-translational histone modifications. We investigated the effects of arsenic on histone residues in vivo as well as in vitro. Analysis of H3K9Ac and H3K9me3 in CD4
Trisomy 7 as the single chromosome aberration has been found in a variety of neoplasms and in normal tissue in the proximity of tumors, as well as in non-neoplastic lesions. Recently, we described a nonrandom pattern of chromosome aberrations, in particular, a gain of chromosome 7, in synovia, cartilage, and osteophytes from patients with osteoarthritis. To study the clonal origin of trisomy 7 in
Innovation plays an important role in organization survival and longevity. This is especially true in the retail industry; there is a growing acknowledgment of the role of innovation in retail practice, as maintaining the status quo might prove insufficient, especially for traditional retailers, in addressing the enormous challenges they are facing driven by technological developments and evolving
This chapter traces the Syrian crisis through the lives of Syrian labourers in Beirut. Lebanon has maintained a significant population of migrant workers for decades. Men undertook largely seasonal work with extended periods of wage labour abroad. However, there was little evidence of permanent settlement and few signs that a second-generation of Syrians settling permanently across the border. The
This paper is about how the Syrian government lost control over its rural and rural-to-urban constituents. From the twin perspective of ethnography and political economy, I show how the same pressures that structured men’s decisions to migrate from the countryside to sell labour power in the city resemble the material foundations for the uprising itself. The dominant narrative of the Syrian uprisi
Jennie Bradbury and Philip Proudfoot reveal how agriculture is at the heart of both strife and heritage in Syria
Att dela med sig av det som växer i ens trädgård kan betraktas som en enkel, vardaglig vänskapsgest eller helt enkelt ett sätt att bli av med något man inte själv har användning för. Det kan emellertid också ses som inslag i större och vidare sammanhang. Ett sätt att tolka fenomenet är att se det som del i en delningsekonomi; ett begrepp som under senare år allt oftare kommit att användas om de fr
Gösta Hellström was a prolific film critic who introduced new film movements into Sweden during the 1920s and 1930s. He also had a short career as a film director, and is especially known for his experimental short Tango (1932). Hellström is a representative of the early cinephilia and of a modernism that was never to be fulfilled in Sweden, at least not in terms of coherent film production. In th
Background: Clinical reasoning is the ability to integrate and apply different types of knowledge, weigh evidence critically and reflect upon the process to arrive at a diagnosis. Body awareness is an approach directed toward an awareness of how the body is used in terms of body function, behaviour, and interaction with self and others. Methods: In the present study, 36 physiotherapists (PTs) from
It is known that any harmonic map of finite uniton number from a Riemann surface into U (n) can be deformed into a new harmonic map with an associated S1-invariant extended solution. We study this deformation in detail using operator-theoretic methods. In particular, we show that the corresponding unitons are real analytic functions of the deformation parameter, and that the deformation is closely
We describe a new and model-independent Lévy imaging method of quality fits to the published datasets and reconstruct the amplitude of high-energy pp and pp¯ elastic scattering processes. This method allows us to determine the excitation function of the shadow profile P(b), the elastic slope B(t) and the nuclear phase ϕ(t) functions of pp and pp¯ collisions directly from the data. Surprisingly, no
Fluorescence polarization is widely used to assess the orientation/rotation of molecules, and the excitation energy transfer between closely located chromophores. Emerging since the 1990s, single molecule fluorescence spectroscopy and imaging stimulate the application of light polarization for studying molecular organization and energy transfer beyond ensemble averaging. Here, traditional fluoresc
Among the many unique flight behaviours of Common Swifts Apus apus, the most puzzling may be their ascents to high altitudes during both dusk and dawn. Twilight ascents have been hypothesized to be functionally related to information acquisition, including integration of celestial orientation cues, high-altitude visual landmarks and sampling of weather conditions. However, their exact purpose rema
Fundamental upper bounds are given for the plasmonic multipole absorption and scattering of a rotationally invariant dielectric sphere embedded in a lossy surrounding medium. A specialized Mie theory is developed for this purpose and when combined with the corresponding generalized optical theorem, an optimization problem is obtained which is explicitly solved by straightforward analysis. In partiFundamental upper bounds are given for the plasmonic multipole absorption and scattering of a rotationally invariant dielectric sphere embedded in a lossy surrounding medium. A specialized Mie theory is developed for this purpose and when combined with the corresponding generalized optical theorem, an optimization problem is obtained which is explicitly solved by straightforward analysis. In parti
To increase fitness, a wide range of vertebrates preferentially mate with partners that are dissimilar at the major histocompatibility complex (MHC) or that have high MHC diversity. Although MHC often can be assessed through olfactory cues, the mechanism by which MHC genes influence odour remains largely unclear. MHC class IIB molecules, which enable recognition and elimination of extracellular ba
