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The intrauterine milieu can have an impact on an individualʼs entire life. Restricted supply not only causes reduced growth, but also irreparable damage, e.g., cardiovascular or neurocognitive. Issues to be addressed by prenatal medicine include not only possible therapeutic aspects, but also the question of the optimal medical strategy, which aims to minimize damage from undersupply on the one ha

Numerical investigation on the impact of membrane thickness on transport phenomena in PEM fuel cells

A two-dimensional mathematical model is used to investigate the performance and transport characteristics of PEM fuel cells with different membrane thicknesses. The overall cell performance of three cases are presented and compared. In addition, the local temperature, liquid water saturation, water content and current density distributions are analyzed and compared. Results show that performance i

Does Self-isolation Violate the Right to Liberty? An Analysis of the European Court of Human Rights’ Practice in Light of the Ukrainian Experience

COVID-19 became a stress-test for many legal systems because it required that a balance be found between rapid action to prevent the spread of the disease and a continued respect for human rights. Many states in Europe, including Ukraine, chose to enforce an obligation to self-isolate. In this article we review what the obligation to self-isolate entails in the case of Ukraine. We also analyse whe

On the convergence rate of the dirichlet-neumann iteration for coupled poisson problems on unstructured grids

We consider thermal fluid structure interaction with a partitioned approach, where typically, a finite volume and a finite element code would be coupled. As a model problem, we consider two coupled Poisson problems with heat conductivities $$\lambda _1$$, $$\lambda _2$$ in one dimension on intervals of length $$l:1$$ and $$l:2$$. Hereby, we consider linear discretizations on arbitrary meshes, such

Ethene/nitrous oxide mixtures as green propellant to substitute hydrazine : Reaction mechanism validation

Reaction mechanism validation for nitrogen-diluted ethane/nitrous oxide mixtures at stoichiometric conditions has been performed using ignition delay time measurements at p = 1, 4, and 16 bar as well as laminar flame speed measurements at p = 1 and 3 bar. The predictive capability of the public domain mechanism GRI 3.0 was improved considerably by adapting some reactions within the nitrogen subsys

Production of moth sex pheromone precursors in Nicotiana spp. : a worthwhile new approach to pest control

Pheromones are environmentally friendly alternatives to traditional pesticides for pest control. They are widely applied for insect monitoring, mating disruption and mass trapping. Nicotiana benthamiana and N. tabacum are potential green biomass production platforms of moth sex pheromones. Using these two Nicotiana species as plant factories, we expressed biosynthetic genes of plant and insect ori

The development of supply chain risk management over time : revisiting Ericsson

Purpose: This invited article explores current developments in supply chain risk management (SCRM) practices by revisiting the classical case of Ericsson (Norrman and Jansson, 2004) after 15 years, and updating its case description and analysis of its organizational structure, processes and tools for SCRM. Design/methodology/approach: An exploratory case study is conducted with a longitudinal focu

Inflammation, oxidative stress and genotoxicity responses to biodiesel emissions in cultured mammalian cells and animals

Biodiesel fuels are alternatives to petrodiesel, especially in the transport sector where they have lower carbon footprint. Notwithstanding the environmental benefit, biodiesel fuels may have other toxicological properties than petrodiesel. Particulate matter (PM) from petrodiesel causes cancer in the lung as a consequence of delivery of genotoxic polycyclic aromatic hydrocarbons, oxidative stress

Self-service Last Mile Delivery : E-consumer perspective on service renovation

The continuous growth of e-retail in the B2C sector has been generating new recordsin revenues for several years. This has led to diversification of the marketinteractions and actors that are involved and impacted by the respective operationsand trends. To address the rising demands from the different actors involved and tohelp manage the increasing complexity of the retail sector, technological s

Body surface rewarming in fully and partially hypothermic king penguins

Penguins face a major thermal transition when returning to land in a hypothermic state after a foraging trip. Uninsulated appendages (flippers and feet) could provide flexible heat exchange during subsequent rewarming. Here, we tested the hypothesis that peripheral vasodilation could be delayed during this recovery stage. To this end, we designed an experiment to examine patterns of surface rewarmPenguins face a major thermal transition when returning to land in a hypothermic state after a foraging trip. Uninsulated appendages (flippers and feet) could provide flexible heat exchange during subsequent rewarming. Here, we tested the hypothesis that peripheral vasodilation could be delayed during this recovery stage. To this end, we designed an experiment to examine patterns of surface rewarm

The metabolic cost of subcutaneous and abdominal rewarming in king penguins after long-term immersion in cold water

Marine endotherms in the polar regions face a formidable thermal challenge when swimming in cold water. Hence, they use morphological (fat, blubber) adjustment and peripheral vasoconstriction to reduce demands for heat production in water. The animals then regain normothermia when resting ashore. In the king penguin (Aptenodytes patagonicus) metabolic rate is lower in fed than in fasted individual

Unacceptable pain in the BARFOT inception cohort of patients with rheumatoid arthritis : a long-term study

Objectives: Pain is the most common and troublesome complaint in rheumatoid arthritis (RA). This study aimed to assess the prevalence and clinical implications of unacceptable pain in an inception cohort of patients with RA. Method: This study followed 477 patients from the BARFOT (Better Anti-Rheumatic FarmacOTherapy) early RA cohort for 15 years. Unacceptable pain was defined as ≥ 40 mm on a vis

The young protester : the impact of belongingness needs on political engagement

As institutional forms of political engagement continue to decline, participation in protests steadily become more common. These trends are particularly strong among younger citizens. Previous research indicates that social factors can explain participation in political protests, and that younger citizens’ participation in protests is more affected by social ties than older people’s participation.

Experiences of sensory input in daily occupations for people with serious mental illness

Background: There is growing evidence that people with serious mental illness have impaired capacity for processing sensory inputs which affects daily occupation. Although this is known, research regarding the target groups experiences of sensory inputs in daily occupations is lacking. Aim: To investigate the experience of sensory input and strategies used in daily occupations among people with se

Informed successive condition assessments in bridge maintenance

The condition assessment of bridges considers a combination of information from different sources rendering multiple levels of assessment possible. This paper illustrates how successive condition assessment strategies increase the expected utility compared to single choice decisions through Bayesian inference. Multiple levels of assessment allow for additional possibilities for obtaining structura

Cerebrospinal fluid levels of GFAP and pNF-H are elevated in patients with chronic spinal cord injury and neurological deterioration

Background: Years after a traumatic spinal cord injury (SCI), a subset of patients may develop progressive clinical deterioration due to intradural scar formation and spinal cord tethering, with or without an associated syringomyelia. Meningitis, intradural hemorrhages, or intradural tumor surgery may also trigger glial scar formation and spinal cord tethering, leading to neurological worsening. S

Serum choline in extremely preterm infants declines with increasing parenteral nutrition

Purpose: Choline is an essential nutrient for fetal and infant growth and development. Parenteral nutrition used in neonatal care lack free choline but contain small amounts of lipid-bound choline in the form of phosphatidylcholine (PC). Here, we examined the longitudinal development of serum free choline and metabolically related compounds betaine and methionine in extremely preterm infants and h