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BACKGROUND: The cross-sectional association between cerebral tissue oxygen saturation (SctO 2) and heart failure (HF) has been previously studied, but the prognostic significance of SctO 2 in HF remains uncertain. This study aimed to assess the role of SctO 2 as a risk factor for all-cause mortality and rehospitalisation, as well as to explore the cross-sectional association between physical activ

The distribution of betony (Betonica officinalis L.) is mapped using 390 herbarium specimens from 31 countries (28 European, 2 African and 1 Asian), representing ca 200 localities. Populations from 19 of these localities were used in seed cultivation experiments. Characters that correlate with their biogeography were searched for both in the herbarium material and in the cultivated material. Three

Objectives Sustained activity of the upper trapezius muscle during work has been linked to the development of neck pain. Women have higher occurrences of neck pain than men, even in the same occupations. This study aimed to investigate sex-specific associations between upper trapezius muscle activity time-related variables and neck pain using a meta-analysis of pooled data. Methods Seven Scandinav

Diabetes is a growing global problem, with hundreds of millions of people living with the disease worldwide. Diabetes can be divided into two major subtypes, autoimmune type 1 diabetes (T1D), and type 2 diabetes (T2D), which has stronger causal links in obesity, lifestyle, and age. Although immunity and inflammation are clearly defined in T1D, it is also understood that inflammation has a role in

The perivascular space (PVS) is integral to glymphatic function, facilitating fluid exchange and waste clearance in the brain. Diffusion tensor imaging along the perivascular space (DTI-ALPS) has been proposed as a noninvasive marker of perivascular diffusion, yet its specificity remains unclear. ALPS measures assume radial symmetry in white matter (characterized by equal transverse diffusion eige

Gut microbial communities can facilitate traits that are essential for invasive species survival in novel environments. Despite the global plethora of invasive social insect species, the role of the gut microbiome in colonisation success under novel dietary and environmental conditions is little known. The introduction of the European buff-tailed bumblebee, Bombus terrestris, to the island of Tasm

Environmental, social and governance (ESG) investing has become a site of struggle,around which a range of actors at multiple scales and in different legal, political andfinancial spheres are mobilising. We delve into four dynamics that characterise thisquickly changing landscape and propose a set of conceptual avenues to analysethem. Gramscian political economy, legal geographies and science and

The Permian - Triassic boundary of the Çürük daǧsection (Taurus, Antalya Nappes, Turkey) was sampled for ostracodes. 38 species belonging to 22 genera were discovered. This ostracode fauna is the first one described throughout the Permian - Triassic boundary outside of South China. Six species are new: Sargentina pamucakensis Crasquin-Soleau n. sp., Bairdia kemerensis Crasquin-Soleau n, sp., Baird

The Siusi/Seis section has been measured for the δ13C signature across the Permian-Triassic Boundary (PTB) in high resolution on magnetostratigraphic samples from Scholger et al. (2000), enabling an exact correlation with magnetostratigraphic data. We show that the base of the short normal polarity magnetozone that has been reported from the evento-stratigraphic boundary correlates with a distinct

Accurately predicting terrestrial ecosystem responses to climate change over long-timescales is crucial for addressing global challenges. This relies on mechanistic modeling of ecosystem processes through land surface models (LSMs). Despite their importance, LSMs face significant uncertainties due to poorly constrained parameters, especially in carbon cycle predictions. This paper reviews the prog

A post-extinction calcimicrobial cap rock occurs above the giant Permian skeletal carbonate platform exposed in the western Taurus Mountains (southern Turkey). It was formed during the main step of a very rapid and large-scale platform flooding (Earliest Triassic) and has been found also in other Tethyan localities. This calcimicrobial cap rock, 20 to 40 pm thick, consists of thrombolitic and stro

Background: Osteoarthritis (OA) and inflammatory arthritis (IA), including rheumatoid arthritis (RA), psoriatic arthritis (PsA), and axial spondylarthritis (axSpA), are leading causes of disability worldwide, significantly impacting health and quality of life. Sleep issues are highly prevalent in these populations, exacerbating pain, fatigue, and disease activity. However, there is a dearth of evi

This special issue introduction explores dialogic organizing centred on affirming public engagement for hope and solidarity. We propose ways of retheorizing and revitalizing dialogic perspectives and practices. In so doing we take our cue a Bakhtinian understanding of dialogue; however, we suggest that it is necessary to move beyond this foundational understanding. Instead, it needs to be read in

Cellular senescence, a phenomenon characterized by the accumulation of dysfunctional, metabolically active cells, is increasingly recognized to be a key player in aging-related metabolic disorders. It is accelerated by hyperglycemia through various molecular pathways, positioning it as a critical mechanism in the pathophysiology of type 2 diabetes mellitus (T2D) and a potential therapeutic target.

In this work, we explore Higgs boson decays into dark matter (DM) within the context of the freeze-in mechanism under stronger coupling scenarios. Our analysis focuses on scalar DM candidates interacting through the Higgs portal, where the coupling strength can be significant without establishing thermal equilibrium, owing to a suppressed reheating temperature. We find that for DM masses as low as

Structural optimization aims to find the geometry of the best performing design in a predefined setting, using mathematical techniques. The motivation for this study can be categorized into three main benefits: efficient material usage, enhancing existing designs and enabling new technologies. All of these benefits are crucial for solving contemporary technological and environmental challenges. An

Large amounts of dendrochronological data sets exported from the SEAD databasehave in this study been used to analyze timber trade and provenance from thethree Scandinavian towns of Copenhagen, Stockholm and Nya Lödöse/Gothenburgduring the medieval and early modern era. In total, 964 dendrochronologicalsamples with a dating and provenance description were compiled in this studyand compared with wrLarge amounts of dendrochronological data sets exported from the SEAD database have in this study been used to analyze timber trade and provenance from the three Scandinavian towns of Copenhagen, Stockholm and Nya Lödöse/Gothenburg during the medieval and early modern era. In total, 964 dendrochronological samples with a dating and provenance description were compiled in this study and compared wi