Aim: The incidence of colorectal cancer (CRC) in Sweden is increasing in individuals

Several studies have shown the association between decreased insulin sensitivity and the risk of male hypogonadism. Homeostatic model assessment of insulin resistance (HOMA-IR) is a well-established marker of decreased insulin sensitivity. The triglyceride-glucose index (TyG), calculated as ln fasting triglyceride mg/dL× fasting glucose mg/dL/2, was recently suggested to be a cheaper and a reliabl

Earlier treatment of breast cancer results in better survival. Screening enables this through detection of tumors before they cause symptoms. On the negative side, some tumors if not detected through screening would not cause symptoms, leading to overdiagnosis. Improvements in image quality allow even earlier detection and diagnosis of even smaller tumors at an even earlier stage. This study aims

In this paper we study the numerical quadrature of a stochastic integral, where the temporal regularity of the integrand is measured in the fractional Sobolev-Slobodeckij norm in Wσ,p(0,T), σ ∈(0,2), p∈[2,∞). We introduce two quadrature rules: The first is best suited for the parameter range σ ∈(0,1) and consists of a Riemann-Maruyama approximation on a randomly shifted grid. The second quadrature

For initial value problems associated with operator-valued Riccati differential equations posed in the space of Hilbert–Schmidt operators existence of solutions is studied. An existence result known for algebraic Riccati equations is generalized and used to obtain the existence of a solution to the approximation of the problem via a backward Euler scheme. Weak and strong convergence of the sequenc

Freeze drying is a commonly used method for preserving probiotic bacteria and live biotherapeutic products. Before drying, the bacterial cells are formulated with a lyoprotectant, and the design of these two process steps are crucial to achieve a high-quality product. There are several factors that may affect the biological and physicochemical properties of the freeze-dried cells and we have used

In this paper, we introduce a randomized version of the backward Euler method that is applicable to stiff ordinary differential equations and nonlinear evolution equations with time-irregular coefficients. In the finite-dimensional case, we consider Carathéodory-type functions satisfying a one-sided Lipschitz condition. After investigating the well-posedness and the stability properties of the ran

Differential equations are an important building block for modeling processes in physics, biology, and social sciences. Usually, their exact solution is not known explicitly though. Therefore, numerical schemes to approximate the solution are of great importance. In this thesis, we consider the temporal approximation of nonlinear, nonautonomous evolution equations on a finite time horizon. We pres

Background: Contemporary patients with pulmonary arterial hypertension (PAH) are older and exhibit cardiovascular or/and lung comorbidities. Such patients have typically been excluded from major PAH drug trials. This systematic review compares baseline characteristics, hemodynamic parameters, and mortality rate between PAH patients with significant number of comorbidities compared to those with fe

With more than 260 000 islands, Sweden is one of the countries with most islands in the world. Its islands are located along the coasts and in the larger lakes. For the municipalities and regions where they are located, the islands are places for recreation and symbols in tourism marketing. A rough overview over the impact of the pandemic on rural and remote areas indicates that Swedish tourism in

A recent rise in climate-related risks, encompassing floods, landslides, storms, and heat waves, has been noted across Sweden, resulting in significant property damage amounting to millions of Euros. While contemporary homes are being developed with climate-resilient designs, the existing housing stock remains exposed to the dynamic challenges of climate hazards. The primary research objective is

The majority of single-family houses in Sweden are affected by deteriorations in building envelopes as well as heating, ventilation and air conditioning systems, since they are about 30 years old. Theses house are therefore in need of extensive renovation, which provides an excellent opportunity to incorporate energy efficiency measures to reduce both the energy consumption and also operational. A

To investigate multimodal signals in cat–human communication we recorded 36 cat–owner interactions in everyday situations that were judged by the owners for valence (negative, mixed or positive). We then coded the videos for behaviour using an ethogram including vocal, visual and tactile (multimodal) signals. Vocalisations were segmented and acoustic measures of duration and F0 obtained. In cats,

Plasma proteomics offers high potential for biomarker discovery, as plasma is collected through a minimally invasive procedure and constitutes the most complex human-derived proteome. However, the wide dynamic range poses a significant challenge. Here, we propose a semi-automated method based on the use of multiple single chain variable fragment antibodies, each enriching for peptides found in up

This thesis addresses the critical issue of design and development of products like production machines for SMEs and rural communities as an essential capability to foster local technology development within the innovation systems of Latin America. What is studied and discussed in this thesis is the pre-requisites for effective application of design and development methods, like design thinking fo

Air pollution is a global health problem and in Mozambique, indoor air pollution is primarily causedby cooking over an open fire. This study examines the potential of coconut charcoal as a cleanercooking fuel and as a possible source of income for women in the village of Linga Linga, Mozambique.Previous research conducted in the village identified a need to investigate the willingness of thecommunAir pollution is a global health problem and in Mozambique, indoor air pollution is primarily caused by cooking over an open fire. This study examines the potential of coconut charcoal as a cleaner cooking fuel and as a possible source of income for women in the village of Linga Linga, Mozambique. Previous research conducted in the village identified a need to investigate the willingness of the co

Energy economists have long argued that energy systems need to be adaptable in the face of shocks. In the early twentieth century, Denmark embodied the opposite, with its industry almost entirely dependent on imports of coal from the UK. Towards the end of the First World War, however, and well into the 1920s, coal imports became expensive and more difficult to obtain. Local diversification was po