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Bomb-pulse 14C analysis combined with 13C and 15N measurements in blood serum from residents of Malmö, Sweden

The 14C content of 60 human blood serum samples from residents of Malmö (Sweden) in 1978, obtained from a biobank, has been measured to estimate the accuracy of 14C bomb-pulse dating. The difference between the date estimated by using the Calibomb software and sampling date varied between -3±0.4 and +0.2±0.5 years. The average age deviation of all samples was -1.5±0.7 years, with the delay between

Protein dynamics: aggregation and mechanical unfolding

The subject of this thesis is protein dynamics. Papers I--IV and VI study either of two different processes: mechanical unfolding and aggregation. Paper V presents a computationally efficient all-atom model for proteins, variants of which are used to perform Monte Carlo simulations in the other papers. Mechanical unfolding experiments probe properties of proteins at the single molecule level. The

Self-reported mindfulness mediates the relation between meditation experience and psychological well-being

A well established notion in Buddhist literature is that meditation practice improves the ability to be mindful in daily life which in turn promotes psychological wellbeing. In order to test this hypothesis the relations between meditation experience, five mindfulness facets and psychological well-being were studied in a sample consisting of Buddhist meditators, Western mindfulness meditators and

Molecular co-operation between protein PAM and streptokinase for plasmin acquisition by Streptococcus pyogenes.

Bacterial surface-associated plasmin formation is believed to contribute to invasion, although the underlying molecular mechanisms are poorly understood. To define the components necessary for plasmin generation on group A streptococci we used strain AP53 which exposes an M-like protein ("PAM") that contains a plasminogen-binding sequence with two 13-amino acid residues long tandem repeats (a1 and