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Poesi som propaganda : Nedslag i historia, tematik och praktik
Långt innan poesin blev kärlekens språk var den maktens och hatets tjänare. Än idag är den ett effektivt vapen i kampen om makt och inflytande. I "Poesi som propaganda" berättar propagandaforskaren Jimmy Vulovic om hur och varför dikten så ofta har tvingats tjäna maktens intressen. Med tematiska nedslag i härskarhymner samt krigs-, seger- och gudsdikter tecknas propagandapoesins historia från kils
Adaptation of Fibril-Reinforced Poroviscoelastic Properties in Rabbit Collateral Ligaments 8 Weeks After Anterior Cruciate Ligament Transection
Ligaments of the knee provide stability and prevent excessive motions of the joint. Rupture of the anterior cruciate ligament (ACL), a common sports injury, results in an altered loading environment for other tissues in the joint, likely leading to their mechanical adaptation. In the collateral ligaments, the patterns and mechanisms of biomechanical adaptation following ACL transection (ACLT) rema
Alison Kafer: Med blicken på funktionsmaktordningen
Adjusting platform business models : Digital health platforms in regulated industries
Digital platforms are spreading very fast and new opportunities are emerging in the realm of digital services. But, can any firm easily succeed with a new platform business model? Well, reality seems to be quite complex. Focusing on digital health platforms as examples of new business models in highly regulated sectors, we outline the challenges that platforms should prepare for.
Shaping Civil Society Leaders: Horizontal and Vertical Boundary Work in Swedish Leadership Training Programmes
Civil society leadership training programmes are a new phenomenon, and they are often overlooked by civil society scholarship despite being linked to the professionalisation of the sector. In this article, we examine 14 Swedish leadership programmes in order to identify leadership ideals in the sector. Drawing on the notion of ‘symbolic boundaries’, we argue that leadership programmes produce hori
Urban and local social policies in the Nordic countries
Nordic welfare states continue to rely on strong central and local governments in the regulation, funding, and implementation of social policies. However, decentralization of particular policy areas (e.g. activation policies) have further increased the significance of the local level in Nordic social policy regulation. However, increasing differences between local entities (e.g. between urban and
RG100204, A Novel Aquaporin-9 Inhibitor, Reduces Septic Cardiomyopathy and Multiple Organ Failure in Murine Sepsis
Sepsis is caused by systemic infection and is a major health concern as it is the primary cause of death from infection. It is the leading cause of mortality worldwide and there are no specific effective treatments for sepsis. Gene deletion of the neutral solute channel Aquaporin 9 (AQP9) normalizes oxidative stress and improves survival in a bacterial endotoxin induced mouse model of sepsis. In t
Gaps and alternative surgical and non-surgical approaches in the bone fragility management : an updated review
Osteoporotic fractures are one of the major problems facing healthcare systems worldwide. Undoubtedly, fragility fractures of the hip represent a far greater burden in terms of morbidity, mortality, and healthcare costs than other fracture sites. However, despite the significant impact on the health and quality of life of older adults, there is a general lack of awareness of osteoporosis, which re
Five year risk assessment and treatment patterns in patients with chronic thromboembolic pulmonary hypertension
Aims: Repeated risk assessments and treatment patterns over long time are sparsely studied in chronic thromboembolic pulmonary hypertension (CTEPH); thus, we aimed to investigate changes in risk status and treatment patterns in incident patients with CTEPH over a 5 year period. Methods and results: Descriptive and explorative study including 311 patients diagnosed with CTEPH 2008–2019 from the Swe
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Impact of dupilumab on SNOT-22 sleep and function scores in CRSwNP
Remissyttrande: Framställning om ändring i bestämmelser om avgifter för årlig revision (2021/22:RR6)
Pandemics, Policing and Protest
Pre-operative exercise and pyrexia as modifying factors in malignant hyperthermia (MH)
Malignant hyperthermia (MH) is a life-threatening reaction triggered by volatile anesthetics and succinylcholine. MH is caused by mutations in the skeletal muscle ryanodine receptor (RYR1) gene, as is rhabdomyolysis triggered by exertion and/or pyrexia. The discrepancy between the prevalence of risk genotypes and actual MH incidence remains unexplained. We investigated the role of pre-operative ex
Test-retest variability of plasma biomarkers in Alzheimer's disease and its effects on clinical prediction models
INTRODUCTION: The effect of random error on the performance of blood-based biomarkers for Alzheimer's disease (AD) must be determined before clinical implementation. METHODS: We measured test-retest variability of plasma amyloid beta (Aβ)42/Aβ40, neurofilament light (NfL), glial fibrillary acidic protein (GFAP), and phosphorylated tau (p-tau)217 and simulated effects of this variability on biomark
A critical role of the mechanosensor PIEZO1 in glucose-induced insulin secretion in pancreatic β-cells
Glucose-induced insulin secretion depends on β-cell electrical activity. Inhibition of ATP-regulated potassium (KATP) channels is a key event in this process. However, KATP channel closure alone is not sufficient to induce β-cell electrical activity; activation of a depolarizing membrane current is also required. Here we examine the role of the mechanosensor ion channel PIEZO1 in this process. Yod
Genomic sequence capture of Plasmodium relictum in experimentally infected birds
Background: Sequencing parasite genomes in the presence of host DNA is challenging. Sequence capture can overcome this problem by using RNA probes that hybridize with the parasite DNA and then are removed from solution, thus isolating the parasite DNA for efficient sequencing. Methods: Here we describe a set of sequence capture probes designed to target 1035 genes (c. 2.5 Mbp) of the globally dist
Pituitary function and the response to GH therapy in patients with Langerhans cell histiocytosis : analysis of the KIMS database
Objective: To analyze the effectiveness and safety of growth hormone (GH) replacement treatment in adult patients with Langerhans cell histiocytosis (LCH) and GH deficiency (GHD) enrolled in KIMS (Pfizer International Metabolic Database). Patients and methods: Patients with LCH and GHD were studied at baseline and some of them after 1 year of GH treatment. The effectiveness of GH is presented as c
Unraveling Parkinson's disease heterogeneity using subtypes based on multimodal data
Background: Parkinson's disease (PD) is a clinically and neuroanatomically heterogeneous neurodegenerative disease characterized by different subtypes. To this date, no studies have used multimodal data that combines clinical, motor, cognitive and neuroimaging assessments to identify these subtypes, which may provide complementary, clinically relevant information. To address this limitation, we su