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Coding of procedures documented by general practitioners in Swedish primary care-an explorative study using two procedure coding systems

Background: Procedures documented by general practitioners in primary care have not been studied in relation to procedure coding systems. We aimed to describe procedures documented by Swedish general practitioners in electronic patient records and to compare them to the Swedish Classification of Health Interventions (KVA) and SNOMED CT. Methods: Procedures in 200 record entries were identified, co

Male inguinal hernia repair with mesh. Short- and long-term results and the question of infertility.

Popular Abstract in Swedish Med stigande ålder försvagas våra vävnader. Om bukväggen i ljumsken blir för svag, så kan bukinnehållet pressas ut genom svagheten. Detta kallas för ljumskbråck. Sjukdomen är mycket vanligare hos män och drabbar alla åldrar. Ju äldre man är, desto vanligare att man drabbas av ett ljumskbråck. Man upplever då, framför allt vid ansträngning, en oftast rörlig och ibland smBackground: In the nineties, the patients with inguinal hernias were exposed to several newly developed repair techniques using alloplastic mesh prosthesis. Although the scientific knowledge was limited, the new techniques were rapidly introduced due to surgical enthusiasm, but also by an eagerness to reduce the recurrence rate and to shorten the time to recovery. When the first study of this thes

Clinical and Genetic Determinants of Progression of Type 2 Diabetes: A DIRECT Study

OBJECTIVETo identify the clinical and genetic factors that explain why the rate of diabetes progression is highly variable between idividuals following diagnosis of type 2 diabetes.RESEARCH DESIGN AND METHODSWe studied 5,250 patients with type 2 diabetes using comprehensive electronic medical records in Tayside, Scotland, from 1992 onward. We investigated the association of clinical, biochemical,

Safety of thalidomide in newly diagnosed elderly myeloma patients: a meta-analysis of data from individual patients in six randomized trials

Treatment with melphalan-prednisone-thalidomide improves the outcome of patients with multiple myeloma and is now considered a standard of care for patients not eligible for transplantation. However, this treatment is a major source of morbidity. A meta-analysis of data from individual patients (n=1680) in six randomized trials was performed, comparing the effects of melphalan-prednisone-thalidomi

Multivariable Optimization-Based Model Reduction

In this technical note we introduce a multivariable extension of a recently proposed model reduction algorithm for linear time-invariant systems. Reduced models are found by solving a convex. optimization problem with Linear Matrix Inequality constraints given a state space model or frequency samples of a model. In order to illustrate the method we apply it to a large-scale model of a deformable m

CaMKII inhibition with KN93 attenuates endothelin and serotonin receptor-mediated vasoconstriction and prevents subarachnoid hemorrhage-induced deficits in sensorimotor function.

It has been suggested that transcriptional upregulation of cerebral artery contractile endothelin (ETB) and 5-hydroxytryptamine (5-HT1B) receptors play an important role in the development of late cerebral ischemia and increased vasoconstriction after subarachnoid hemorrhage (SAH). We tested the hypothesis that inhibition of calcium calmodulin-dependent protein kinase II (CaMKII) may reduce cerebr

Generating research questions through problematization

It is increasingly recognized that what makes a theory interesting and influential is that it challenges our assumptions in some significant way. However, established ways for arriving at research questions mean spotting or constructing gaps in existing theories rather than challenging their assumptions. We propose problematization as a methodology for identifying and challenging assumptions under

Fetch! Go away! Sit! – Feeling at home in contemporary Sweden

This article analyzes Natan against the background of an increasingly mobile world where social relations and practices have become disembedded and social capital decreases. Natan outlines an inability to feel at home in modern society, and counters this experience by restoring a nostalgic home for a seemingly homeless man.

Mapping the Mayo-Portland adaptability inventory to the international classification of functioning, disability and health

Objective: To examine the contents of the Mayo-Portland Adaptability Inventory (MPAI-4) by mapping it to the International Classification of Functioning, Disability and Health (ICF). Methods: Each of the 30 scoreable items in the MPAI-4 was mapped to the most precise ICF categories. Results: All 30 items could be mapped to components and categories in the ICF. A total of 88 meaningful concepts wer

Receptor for detection of a Type II sex pheromone in the winter moth Operophtera brumata

Abstract in Undetermined How signal diversity evolves under stabilizing selection in a pheromone-based mate recognition system is a conundrum. Female moths produce two major types of sex pheromones, i.e., long-chain acetates, alcohols and aldehydes (Type I) and polyenic hydrocarbons and epoxides (Type II), along different biosynthetic pathways. Little is known on how male pheromone receptor (PR) gHow signal diversity evolves under stabilizing selection in a pheromone-based mate recognitionsystem is a conundrum. Female moths produce two major types of sex pheromones, i.e., long-chainacetates, alcohols and aldehydes (Type I) and polyenic hydrocarbons and epoxides (Type II), alongdifferent biosynthetic pathways. Little is known on how male pheromone receptor (PR) genes evolvedto perceive the

Novel risk factors for atrial fibrillation in an urban population

Popular Abstract in Swedish Förmaksflimmer är den vanligaste rytmrubbningen i hjärtat. Man beräknar att 1-2% av befolkningen har förmaksflimmer. Förmaksflimmer blir vanligare med stigande ålder. Bland personer äldre än 75 år har 5-10% förmaksflimmer. Var fjärde person över 40 år riskerar att drabbas av förmaksflimmer någon gång i livet. Förmaksflimmer ger bl.a. en ökad risk för blodproppar och strAtrial fibrillation (AF) is the most common sustained cardiac arrhythmia in the general population, and a major cause of morbidity and mortality. Low-grade inflammation, erythrocyte volume variation, and subclinical atherosclerosis have repeatedly been associated with cardiovascular disease, but it remains unclear whether these risk factors are also associated with incident AF. This thesis is bas

Should the acceptable noise level be considered to be an acceptable noise range?

The acceptable noise level (ANL) test is used to quantify the amount of competing background noise (BNL) that a listener is willing to accept when listening to speech at the most comfortable level (MCL). ANL is calculated by subtracting the BNL from the MCL. Most studies show large intersubject ANL variability and a few also demonstrate large intrasubject variability. Very few predictor variables

Comparison of measured with calculated dose distribution from a 120-MeV electron beam from a laser-plasma accelerator

Purpose: To evaluate the dose distribution of a 120-MeV laser-plasma accelerated electron beam which may be of potential interest for high-energy electron radiation therapy. Methods: In the interaction between an intense laser pulse and a helium gas jet, a well collimated electron beam with very high energy is produced. A secondary laser beam is used to optically control and to tune the electron b

A novel B(weak) hybrid allele lacks three enhancer repeats but generates normal ABO transcript levels.

Background and Objectives Weak expression of A/B histo-blood group antigens is often explained by single nucleotide substitutions at the ABO locus. However, hybrid alleles containing segments from different ABO alleles can result in unexpected phenotypes and may complicate genotype analysis. We investigated the basis of weak B phenotype in a referred sample. Materials and Methods A healthy young w

Natural Establishment of Specialist Plant Species after Topsoil Removal and Soil Perturbation in Degraded Calcareous Sandy Grassland

Specialist plant species in calcareous sandy grasslands are threatened by acidification and high nutrient levels in the topsoil. We investigated whether topsoil removal and soil perturbation in degraded sandy grasslands could lead to establishment of specialist species belonging to the threatened xeric sand calcareous grassland habitat. Restoration actions performed in 2006 resulted in increased s