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Endoderm development is an area of intense interest in developmental biology, but progress has been hampered by the lack of specific markers for differentiated endodermal cells. In an unbiased secretion cloning screen of Xenopus gastrula embryos we isolated a novel gene, designated Darmin. Darmin encodes a secreted protein of 56 kDa containing a peptidase M20 domain characteristic of the glutamate
Regeneration of cells in the central nervous system is a process that might be affected during neurological disease and trauma. Because nitric oxide (NO) and its derivatives are powerful mediators in the inflammatory cascade, we have investigated the effects of pathophysiological concentrations of NO on neurogenesis, gliogenesis, and the expression of proneural genes in primary adult neural stem c
Low-energy particle production perpendicular to the event plane in three-jet events produced in Z decays in e(+)e(-) annihilation is measured and compared to that perpendicular to the event axis in two-jet events. The topology dependence of the hadron production ratio is found to agree with a leading-order QCD prediction. This agreement and especially the need for the presence of a destructive int
In Swedish public debate, economists have been more influential than any other category of social scientists. We examine the views of five great Swedish economists on the role of the university economist in the public arena. What did they say about scholarly objectivity and value judgements, about political commitment and educating the people? The five economists are Knut Wicksell, Gustav Cassel,
A novel process for the production of biodegradable lubricant-based stocks from epoxidized vegetable oil with a lower pour point via cationic ion-exchange resins as catalysts was developed. This involves two steps, first, ring-opening reactions by alcoholysis followed by esterification of the resultant hydroxy group in the first step. The ring-opening reaction of epoxidized soybean oil with differ
In the first essay of this thesis we develop a model for calculating the net expected value of a swap agreement subject to dual-default risk. The main explanatory variable for the net expected return of a swap is the default intensity of each party measured by the credit rating of the firm. We derive the net expected return of the swap as a function of the credit rating of the firm receiving the f
In this paper, we are concerned with the charging and electrokinetic behavior of colloidal particles exhibiting a high surface charge in the alkaline pH range. For such particles, a theoretical approach has been developed in the framework of the primitive model. The charging and electrokinetic behavior of the particles are determined by the use of a Monte Carlo simulation in a grand canonical ense
We have analysed 994 sites for oncogenes and tumour suppressor genes located within human chromosome bands. The data presented disclose that: 1) These cancer genes build ridges as well as hot spots, which are not related to the position of other types of genes present in these chromosomes. 2) The frequency of cancer genes is not directly related to chromosome length, to the number of DNA bases per
Class I and class II MHC-restricted T cells specific for proteins present in myelin have been shown to be involved in autoimmunity in the central nervous system (CNS). It is not yet known whether CD1d-restricted T cells reactive to myelin-derived lipids are present in the CNS and might be targeted to influence the course of autoimmune demyelination. Using specific glycohpid-CD1d tetramers and clon
This article discusses Swedish gender equality policy and excellent gender equality laws. The problem is not a lack of policy documents and laws, the problem is turning this law system in to practise.
The purpose of this report is to give the background of the chosen methodology to analyse cost-benefit of industrial fire protection. Further more the investigation work has been compiled and some future research topics have been suggested.
Om den politiska svartlistningen av filmarbetare i den amerikanska filmindustrin under 1940- och 1950-talen.
Looking backwards the history of Swedish is characterized by the growing impportance of written language, increased standardization of written and spoken language, growth of the Swedish vocabulary. It is hypothesized that this development will stagnate in the future. The hypothesis ist tested in a discussion against the background of a number of societal phenomena that can be expected to affect th
