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Normative values of the vibration perception thresholds at finger pulps and metatarsal heads in healthy adults

Aims To establish normative values of vibration perception thresholds (VPTs), using multi-frequency vibrometry at finger pulps and at metatarsal heads of the foot in healthy adults. We also aimed to investigate factors that could potentially affect VPTs such as age, sex, height, weight, foot- or handedness and skin temperature. Methods VPTs were examined in 924 healthy and randomly selected subjec

Socioeconomic and clinical predictors of mortality in patients with acute dyspnea

Background: Factors predicting long-term prognosis in patients with acute dyspnea may guide both acute management and follow-up. The aim of this study was to identify socioeconomic and clinical risk factors for all-cause mortality among acute dyspnea patients admitted to an Emergency Department. Methods: We included 798 patients with acute dyspnea admitted to the ED of Skåne University Hospital, M

Karaktärsbevisning : - studier av relevansproblematik i personrelaterad bevisning

This dissertation is a compilation thesis on character evidence in the Swedish legal system. It consists of five articles published in scientific journals and a comprehensive introductory chapter (kappa) on the key concepts, methodology, and procedural law with regard to character evidence in the Swedish system. The dissertation investigates how character evidence is assessed in Swedish courts, an

COVID-19 herd immunity in the absence of a vaccine : an irresponsible approach

As severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) continues to spread rapidly throughout the human population, the concept of "herd immunity" has attracted the attention of both decision-makers and the general public. In the absence of a vaccine, this entails that a large proportion of the population will be infected to develop immunity that would limit the severity and/or extent of

Severe alpha-1-antitrypsin deficiency increases the risk of venous thromboembolism

Background: Severe alpha-1-antitrypsin deficiency (AATD), phenotype PiZZ, is associated with increased risk of liver disease and chronic obstructive pulmonary disease (COPD), but the risk of venous thromboembolism (VTE) is unknown. Our aim was to evaluate the risk of VTE in individuals with severe AATD compared with control subjects from the general population. Methods: Individuals with severe AAT

Diagnostic accuracy of the HEART Pathway and EDACS-ADP when combined with a 0-hour/1-hour hs-cTnT protocol for assessment of acute chest pain patients

Background/aim: In ED chest pain patients, a 0-hour/1-hour protocol based on high sensitivity cardiac troponin T (hs-cTnT) tests combined with clinical risk stratification in diagnosing acute coronary syndrome is recommended. Two of the most promising risk stratification tools are the History, ECG, Age, Risk Factors and Troponin (HEART) and Emergency Department Assessment of Chest Pain (EDAC) scor

Inhibition of STAT3 augments antitumor efficacy of anti-CTLA-4 treatment against prostate cancer

There is an urgent need for new treatment options in metastatic drug-resistant prostate cancer. Combining immunotherapy with other targeted therapies may be an effective strategy for advanced prostate cancer. In the present study, we sought to investigate to enhance the efficacy of anti-CTLA-4 therapy against prostate cancer by the combination with STAT3 inhibition. Male C57BL6 mice were subcutane

Heparin binding protein in severe COVID-19- A prospective observational cohort study

Background and aims Neutrophil-derived heparin binding protein (HBP; also known as azurocidin or CAP-37) is a key player in bacterial sepsis and a promising biomarker in severe infections. The aims of this study were to assess whether HBP is involved in the pathophysiology of COVID-19 and, if so, whether it can be used to predict severe disease preferably using a point-of-care test. Methods This w

Brokers’ list price setting in an auction context

Purpose: The role of list price is often discussed in a narrative describing sellers’ preferences or sellers’ price expectations. This paper aims to investigate a set of list price strategies that real estate brokers have available to influence the outcome of the sale, which may be many times self-serving. Design/methodology/approach: By analyzing real estate brokers’ arguments on the choice of th

How young people talk about their variations in sex characteristics : making the topic of intersex talkable via sex education

Classrooms are important spaces for young people with variations in sex characteristics and their classmates. Sex education can promote agency and well-being by helping young people make sense of their embodiment and form rewarding social relationships and by changing societal understandings about variations in sex characteristics. Realising this potential however may hinge on how sex education ma

The heritability of doctor-diagnosed traumatic and degenerative meniscus tears

Objective: To estimate the genetic contribution to traumatic and degenerative meniscus tears for men and women across the lifespan. Methods: We linked the Swedish Twin Register with individual-level national healthcare data to form a 30-year, population-wide, longitudinal twin cohort. To study genetic contribution to meniscus tears, we estimated the heritability and familial risk using incident tr

(Un)desirable approaches in therapy with Swedish individuals practicing BDSM : client’s perspectives and recommendations for affirmative clinical practices

This transformative study aimed to explore how people who practice BDSM (bondage, discipline, dominance, submission, sadism, masochism) experience therapy; specifically, what sort of therapist responses and qualities they described as problematic and desirable in relation to addressing BDSM in therapy. Semi-structured interviews were conducted with 27 Swedish BDSM practitioners with experiences ofThis transformative study aimed to explore how people who practice BDSM (bondage, discipline, dominance, submission, sadism, masochism) experience therapy; specifically, what sort of therapist responses and qualities they described as problematic and desirable in relation to addressing BDSM in therapy. Semi-structured interviews were conducted with 27 Swedish BDSM practitioners with experiences of

Contextualising Feminisms in the Nordic Region : Neoliberalism, Nationalism, and Decolonial Critique

In understanding feminism as a floating signifier, the chapter seeks to explore how feminism as an idea, a project, and a community of belonging is produced and given meaning to by actors inside and outside of feminisms, but also how feminism is acted upon in different contexts in the Nordic region. The chapter outlines the book’s contribution to the study of the intersections between feminism, ne

Emission reduction strategies in the EU steel industry : Implications for business model innovation

The European steel industry must achieve deep greenhouse gas emission reductions to become climate neutral by 2050. New business models are often proposed as one of the key solutions but are mostly addressed in general terms, without elaborating on or systematically analyzing how these new business models are actually linked to specific mitigation measures or strategies. In this paper, we assess w

Flow structure and heat transfer characteristics in a ribbed two-pass channel with varying divider inclination angle

A numerical method is utilized in this paper to study the effects of varying divider inclination angle on the flow structure and heat transfer characteristics in a ribbed two-pass channel for Reynolds number varying from 10,000 to 50,000. The studied divider inclination angles are −3°,−2°,−1°,0°, +1°, +2° and +3°. The ribs have an orientating angle of 45°. The results show that the heat transfer i

Conclusion : Civil Defence Futures (Re)imagined

Reflecting on the individual studies of civil defence during the Cold War provided in this volume, this brief, concluding chapter performs three tasks. First, against the backdrop of the empirical analyses and the collective exploration of the concept of sociotechnical imaginaries, we reflect on the potential and limitations of this concept in historical scholarship. Second, we sum up the findings

Introduction: New Paths in Civil Defence History

The introduction to the volume lays out the rationale and ambitions of the book, delineates its chronological and geographical focus and situates it in the existing historiography of civil defence. One central ambition is to advance civil defence history by attuning it more explicitly to the study of science and technology and to pave the way for transnational and comparative efforts. We do so in

The Emerging Outer Space Order : Professional Orders, Heterarchy, Hypermodernity and Political Reason

Den politiska ordningen i rymden har tidigare betraktats som en förlängning av den politiska ordningen på jorden. I den här avhandlingen hävdar jag istället att den framväxande politiska ordningen i rymden definierar internationella förhållanden på jorden. Nya insikter om den politiska dynamiken i rymden ger oss därför en bättre förståelse för den nuvarande världsordningen. Dessutom ger en fördjupPolitical order in outer space has so far been perceived as an extension of the terrestrial political order. In contrast, I argue that the political order emerging in outer space defines international relations on Earth. Therefore, with a refreshed understanding of the political dynamics of outer space, we will be better equipped to grasp the contemporary world order. Moreover, deeper knowledge ab