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The development of monoclonal antibody therapies targeting specific components of the pathways relevant to asthma pathophysiology has revolutionized treatment of severe asthma both in adults and children and helped to further unravel the heterogeneity of this disease. However, the availability of multiple agents, often with overlapping eligibility criteria, creates a need for pragmatic guidance fo
A test of CP invariance in Higgs boson production via vector-boson fusion has been performed in the H→γγ channel using 139 fb^{-1} of proton-proton collision data at sqrt[s]=13 TeV collected by the ATLAS detector at the LHC. The optimal observable method is used to probe the CP structure of interactions between the Higgs boson and electroweak gauge bosons, as described by an effective field theo
The prevalence of alopecia has increased recently. Hair loss is often accompanied by the resting phase of hair follicles (HFs). Dermal papilla (DP) plays a crucial role in HF development, growth, and regeneration. Activating DP can revive resting HFs. Augmenting WNT/β-catenin signaling stimulates HF growth. However, the factors responsible for activating resting HFs effectively are unclear. In thi
In this study I have investigated the various factors influencing reproductive tactics among breeding blue tits (Parus caeruleus). The study was carried out in a nestbox-breeding population of marked individuals at the Revinge Area, outside Lund, southern Sweden. I have especially investigated the energetic, physiological and temporal factors influencing the reproductive decisions. This included u
The radionuclide 14C is produced in all types of nuclear reactors mainly by neutron-induced reactions in oxygen (17O), nitrogen (14N) and carbon (13C). Part of the 14C created is continuously released during normal operation as airborne effluents in various chemical forms (such as CO2, CO and hydrocarbons) to the surroundings. Because of the biological importance of carbon and the long physical ha
There is ample evidence that word order is a problematic domain in L2 usage. In particular, production of the verb-second (V2) phenomenon, which requires the finite verb in main clauses to appear in second position, (e.g., Ganuza, 2008 for an overview). Surprisingly, we know very little about how these structures are processed and how production relates to comprehension. We therefore examined how
INTRODUCTION: The importance of holidays, traditions, and family celebrations to human culture and occupational engagement has been neglected. The aim of this study was to explore how older adults experienced holidays and celebrations with social and physical distancing during the COVID-19 pandemic.METHODS: A secondary analysis was made on data from the At-Risk Study. Seventeen community-living ad
In recent years, kaempferol, a natural flavonoid present in various fruits and vegetables, has received significant attention in gastrointestinal cancer research due to its varied therapeutic effects. Kaempferol has been proven to alter several molecular mechanisms and pathways, such as the PI3/Akt, mTOR, and Erk/MAPK pathway involved in cancer progression, showing its inhibitory effects on cell p
