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In this interview, Prince Sisowath Thomico, a cousin of Cambodian King Sihamoni who has been politically active in a range of political movements and parties, discusses the role of the monarchy and what royalism might mean in Cambodia today, three decades after the Cambodian monarchy was reintroduced. He reflects on the historical trajectory of the Cambodian monarchy and royalism, and analyses how

En viktig del av utvecklingen av den fysiska butiken är nya koncept, både som ett sätt att spegla den digitala utvecklingen (med omnikanal som ambition) men också som ett sätt att spegla en förändrad värld där nya konsumentbehov etcetera spelar en viktig roll. Men klarar sig nya format om inte också sättet att utvärdera dem förändras? Den traditionella utvärderingen med försäljning som bas behöver

Conflicting findings have recently been presented as to the sites and sources of B cells that undergo class switch recombination (CSR) to IgA in the gut. In this study we provide compelling evidence in CD40-/- mice demonstrating that IgA CSR can be independent of CD40 signaling and germinal center formation and does not occur in the gut lamina propria (LP) itself. We found that CD40-/- mice had ne

Crayfish spermatophores are deposited on the body surface of the female during mating and remain there for a period of time before fertilization ensues. Post-mating changes in protein expression level in the noble crayfish Astacus astacus spermatophore were quantified. In-gel digestion and high resolution mass spectrometry were used for label-free protein quantification. One hundred twelve protein

Natural killer (NK) cells are large granular lymphocytes that are components of the innate immune system. These cells are key players in the defense against viral and other microbial infections and cancer and have an important function during pregnancy, autoimmunity and allergy. Furthermore, NK cells play important roles in hematopoietic stem cell (HSC) transplantation by providing the graft versu

Introduction: Asthma is a complex, heterogeneous and mutifactorial disease and represents a major health problem in Westernised countries. The airway epithelium, with its direct physical contact with luminal triggers, has a major role in determining the nature of inflammation that develops in asthmatic airways. Objective: The present review aims to provide a brief overview of the numerous ways the

We have recently found that DNA packaged in phage λ undergoes a disordering transition triggered by temperature, which results in increased genome mobility. This solid-to-fluid like DNA transition markedly increases the number of infectious λ particles facilitating infection. However, the structural transition strongly depends on temperature and ionic conditions in the surrounding medium. Using ti

To distinguish between natural and anthropogenic forcing, the supposedly ongoing global warming needs to be put in a longer, geological perspective. When the last ca. 20 000 yr of climate development is reviewed, including the climatically dramatic period when the Last Ice Age ended, the Last Termination, it appears that the last centuries of globally rising temperatures should be regarded as an a

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As the concept of gentrification celebrates an even forty years, some of the most basic questions about the process itself remain contentious. What is gentrification? What are its root causes? There is surely no lack of answers, though these are largely stamped by disciplined convention. The purpose of this chapter is to revisit these basic questions and formulate answers that facilitate “having g

The activation of dendritic cells (DCs) by microbes is mediated by pattern recognition receptors including the Toll-like receptors (TLR). Bacterial lipopolysaccharide acts via TLR4 whereas peptidoglycan and lipoprotein responses are mediated by TLR2. It is generally accepted that TLR binding to microbes occurs at the cell surface but this has not been directly demonstrated for human DCs. We show h

Popular Abstract in Swedish Teknisk textil är en bred benämning för textila material med användningsområden som inte är beklädnad eller där utseendemässiga krav oftast är av underordnad betydelse. På senare tid har dock designsynpunkter på tekniska textilprodukter kommit att alltmer uppmärksammas och detta belyses i kapitel 10 i avhandlingen. Teknisk textil är en nygammal industrigren som genomgåtIn this thesis the tensile strength, deformation, damage resistance and tear propagation for flexible composites are analysed. There are two essential requirements common to all flexible composites; namely, high tearing strength and good matrix-to-fabric adhesion. The interaction of fabric and matrix is complex. The most critical variables are those of yarn and fabric structure, the mechanical pro