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The aim of this study was to determine the clinical conditions of patients with haemophilia within Europe as recommended by the European Commission. In this multicentre, cross-sectional, ambispective study, conducted within 21 European countries patients' clinical data were collected, amongst others haemophilia type, severity, treatment pattern, use of factor products, bleeding, orthopaedic joint
The terrestrial biosphere is a key regulator of atmospheric chemistry and climate. During past periods of climate change, vegetation cover and interactions between the terrestrial biosphere and atmosphere changed within decades. Modern observations show a similar responsiveness of terrestrial biogeochemistry to anthropogenically forced climate change and air pollution. Although interactions betwee
What's known on the subject? and What does the study add? Androgen stimulation of prostate cancer (PCa) cells has been the basis for extensive studies evaluating the role of androgen in PCa but the diagnostic measurement of androgen as well as androgen values that potentially influence prognosis are unclear in patients with PCa. The 50 ng/dL threshold has been questioned as a result of reports ind
We analyze a model for the Higgs sector with two scalar doublets and a Z(2) symmetry that is manifest in the Yukawa sector but broken in the potential. Thus, one of the doublets breaks the electroweak symmetry and has tree-level Yukawa couplings to fermions, whereas the other doublet has no vacuum expectation value and no tree-level couplings to fermions. Since the Z(2) parity is broken the two do
Regarding the recently published review "Looking for new treatments of Infantile Colic" by Savino et al. we want to add that positive effects of acupuncture have been demonstrated to release pain and agitation and that acupuncture seems to be a safe treatment when performed by trained acupuncturists. Inconclusive results in the few published articles on the subject can be due to different acupunct
The first part of this paper aims at identifying the timing of famines in the Nordic countries since the middle ages. This is done by using qualitative famine reports from the literature since quantitative data on famines are scarce or non-existent, at least before the early modern period. We supplement the reports with climate data and price data. Our survey indicates that widespread famine was a
We offer an analysis of perceptual intersubjectivity (PI) in terms of two types (symmetric and asymmetric) and three levels: synchronous (SPI), coordinated (CPI) and reciprocal (RPI), defined on the basis of the observable behavior of the participants in a study of (non-verbal) social interaction. We hypothesize that the three levels constitute stages in the development and possibly evolution of h
Popular Abstract in Swedish BAKGRUND Fokus riktas allt mer mot försörjningskedjan och allt mindre mot det enskilda företaget i takt med att konkurrens mellan enskilda företag ersätts av konkurrens mellan försörjningskedjor. Det är emellertid endast det enskilda företaget som kan fatta beslut och vidta åtgärder, men dessa beslut och åtgärder måste idag ske utifrån ett kedjeperspektiv. Med ökat foBackground Today's modern, industrialized society is based on globalization, specialization and mass-production. It is a society dependent upon highly integrated, continuously ongoing supply chain flows. Disruptions in those flows may cause devastating negative consequences, both for the individual company, for the supply chain, and for the society at large. Purpose and objectives The purpose o
Popular Abstract in Swedish Utforskar äldre och funktionshindrades behov av planeringsinformation i kollektivtrafiken och diskuterar huruvida information kan bidra till tillgängligheten. En omfattande enkätundersökning genomfördes för att validera tidigare genomförda fokusgruppsintervjuer om äldre och funktionshindrades informationsbehov. Resultaten visar att det finns ett behov av information blaExplores elderly and disabled people's travel information requirements when planning a journey by public transport and discusses the potential of information to improve access to the public transport system. Quesionnaire study in order to validate an earlier focus-group interview study about elderly and disabled people's travel information requirements. Results show a need for travel information t
