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Popular Abstract in Swedish Bakgrund: Ischemisk hjärtsjukdom (IHS) och slaganfall är de främsta orsakerna till morbiditet och mortalitet i västvärlden och är ett stort hälsoproblem för samhället. Kardiovaskulära läkemedel används med syfte att förebygga (t. ex. blodtryckssänkande läkemedel och lipidsänkande läkemedel) eller lindra (t. ex. nitrater) dessa sjukdomar. Den optimala effektiviteten ("efBackground: Ischaemic heart disease (IHD) and stroke are the main causes of morbidity and mortality in developed countries and hence constitute a large public health problem. Cardiovascular drugs are used in an effort to prevent (e. g. blood pressure lowering drugs (BPLD) and lipid lowering drugs) and palliate (e. g. nitrates) these disorders. The efficacy and safety of these drugs have been evalu

This thesis aims at analysing and discussing the rules and opportunities of using permanent establishment within financial structures. Financing structures between related parties can be seen as one of the most common tax planning tools for MNE´s. This planning is tackled by thin capitalization rules and is also under the observation of the transfer pricing guidelines. Whereas permanent establishm

Objectives: Old-generation drug-eluting coronary stents (o-DES) have despite being safe and effective been associated with an increased propensity of late stent thrombosis (ST). We evaluated ST rates in o-DES, new-generation DES (n-DES) and bare metal stents (BMS) the first year (< 1 year) and beyond 1 year (> 1 year). Methods: We evaluated all implantations with BMS, o-DES (Cordis Cypher, Boston

Explaining the ∼5-million-year delay in marine biotic recovery following the latest Permian mass extinction, the largest biotic crisis of the Phanerozoic, is a fundamental challenge for both geological and biological sciences. Ocean redox perturbations may have played a critical role in this delayed recovery. However, the lack of quantitative constraints on the details of Early Triassic oceanic an

Preeclampsia (PE) is an important pregnancy complication that affects 3-8% of women worldwide and is a leading cause of maternal and fetal morbidity and mortality. It is known that PE is associated with placental dysfunction, resulting in hypoxia, oxidative stress, altered metabolism and production of inflammatory cytokines. Hypoxia could enhance erythropoiesis and induce non-erythroid hemoglobin

Innovation and entrepreneurship are essential processes for human development, market growth, and technological breakthroughs, and it is vital for economic growth. Despite its importance, innovation is inherently difficult to measure and hence it is almost impossible for an individual or organization to know how they can improve their innovation output or claim that they are great at innovation. T

This study compares the media discourses on euroscepticism in 2014 in six countries (the UK, Ireland, France, Spain, Sweden and Denmark). We assessed the extent to which the mass media's reporting of euroscepticism indicates the Europeanization of public spheres. Using a mixed-methods approach combining latent Dirichlet allocation (LDA) topic modelling and qualitative coding, we find that approxim

Frågeställning: - Vilka av en charterresas komponenter anser resenärer vara viktiga respektive mindre viktiga att charterarrangörer tar ansvar och kompenserar för vid missnöje hos kunden för att skapa en nöjd kund? Syfte och bidrag: Syftet med denna kandidatuppsats är att analysera vilka komponenter i en charterresa som resenärer anser vara viktiga respektive mindre viktiga, med fokus på ansvar oc

The expansion of biotechnology applied to agriculture has drastically changed traditional farming in recent decades. New plant varieties and techniques developed by life-science corporations guarantee more efficiency than traditional methods at relatively low costs. This feature resulted in many biotech creations (such as GM plants) being rapidly adopted by countries with agriculture-based economi

This project was conducted as a phenomenological study, focusing on organizational culture connected to communication, of the collaboration between the academic world and small private companies. The purposes were to get a deeper understanding of culture and communication and to use phenomenology as a research approach, to see what it can contribute with. Data collection was obtained by an intern

The Convention on the Rights of the Child is a legal framework stating what rights children have. Street children also have all these rights but few countries have responded to this. The Convention is however the most widely ratified multi-national treaty in existence and have been ratified by all countries known to deprive street children of their rights. This Master thesis uses the situation in

In a previous paper, a comprehensive clinicopathologic approach to mild and moderate bleeding disorders (MBD) was proposed by an international working group (IWG) as a part of a project promoted by the European Hematology Association (EHA) on the development of guidelines on the various MBDs. A single pre-diagnosis grade 4 bleeding event according to the ISTH-BAT scale or a comparable event after

Adeno-associated viral vectors have become a leading choice for gene therapy in the central nervous system due to their safety profile, efficient neuronal transduction, and capacity for sustained transgene expression. We previously reported that AAV2-derived capsids developed using the BRAVE (Barcoded Rational AAV Vector Evolution) approach have enhanced retrograde transport properties in the rode