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A new look at a poorly immunogenic neutralization epitope on cytomegalovirus glycoprotein B. Is there cause for antigen redesign?

he immune response is able to control cytomegalovirus infection in most subjects. However, in some patient groups the virus is not well contained resulting in disease and severe morbidity. The development of efficacious vaccines is therefore a high priority. Antibodies may contribute to protection against disease caused by CMV but the most efficient targets for protective humoral immunity are not

Cygnet or ugly duckling – what makes the difference? A tale of heat-pump market developments in Sweden

Who can pick a winner? Since 1974, various types of targeted support have at different times been directed at the development of the heat pump market in Sweden – which in the following decades oscillated violently between soaring sales and collapse. Eventually, however, small heat pumps for space heating of residential buildings have in recent years securely established themselves as a mature and

Proceedings utvecklingskonferens 09

I år var andra gången som Lunds universitet genomförde en universitetsgemensam pedagogisk utvecklingskonferens, första gången var 2007. Konferensen, som är ett samarrangemang mellan samtliga fakulteter och CED, har nu alltså blivit en återkommande aktivitet! Samhällsvetenskapliga fakulteten stod värd för årets konferens och dekanus Ann-Katrin Bäcklund sträckte vid invigningen fram en symbolisk sta

The role of glycosaminoglycan binding of staphylococci in attachment to eukaryotic host cells

Attachment of microorganisms to host cells is believed to be a critical early step in microbial pathogenesis. The aim of the study was to determine the role of the known glycosaminoglycan (GAG) binding activity of Staphylococcus aureus and coagulase-negative staphylococci (CoNS) in their attachment to six different eukaryotic cell lines. Three staphylococcal species expressing GAG binding capacity