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Incretin-based therapy is associated with low risk of hypoglycemia in type 2 diabetes mellitus (T2DM) possibly due to its glucose-dependency in stimulating insulin secretion and a sustained glucagon response during hypoglycemia. This is of special relevance when it is combined with insulin or given to elderly patients since both insulin therapy and high age are associated with impaired glucagon co
De stora miljö- och samhällsproblemen kommer inte ensamma. De är sammankopplade på olika sätt. Detta innebär utmaningar men ger också möjligheter att utveckla åtgärder och lösningar. Det gäller både för klimatfrågan och frågan om att motverka förlusten av biologisk mångfald och ekosystem. Kunskapens betydelse för att hantera dessa och andra aspekter är ovärderlig, såväl kring specifika frågeställn
Vegetation is an important component of the terrestrial ecosystem that plays an essential role in the exchange of water and energy in climate and biogeochemical cycles. This study investigated the spatiotemporal variation of normalized difference vegetation index (NDVI) in northern China using the GIMMS-MODIS NDVI during 1982–2018. We explored the dominant drivers of NDVI change using regression a
Executive functions (EF) denote the host of top-down mental processes that mediate self-regulation to achieve a goal. Among other things, EF support cognitive flexibility by allowing inhibition of automatic responses in favour of obtaining future goals. Corvids, the bird group that is comprised of ravens, crows and jays, are distinguished by their cognitive flexibility. This thesis investigates tw
Our knowledge of the molecular mechanisms of urinary tract infection (UTI) pathogenesis has advanced greatly in recent years. In this review, we provide a general background of UTI pathogenesis, followed by an update on the mechanisms of UTI susceptibility, with a particular focus on genetic variation affecting innate immunity. The innate immune response of the host is critically important in the
Swedish archaeologists have been working in Pompeii since 2000. Our fieldwork has consisted mainly of the study of standing walls and cleared floor levels in a city block unearthed in the 19th century and of the production of a comprehensive documentation, presented in an open access publication: www.pompejiprojektet.se/insula.php. The perspective of the present paper is the insula as a whole. Its
OBJECTIVES: Alzheimer disease (AD) can now be diagnosed in subjects with mild cognitive impairment (MCI) using biomarkers. However, little is known about the rate of decline in those subjects. In this cohort study, we aimed to assess the conversion rate to dementia and identify prognostic markers in subjects with MCI and evidence of amyloid pathology. METHODS: We pooled subjects from the VU Un
Background/AimsThe reactive hyperaemia index (RHI) assesses endothelial function, with a proposed cut-off of <1.67 for prevalent endothelial dysfunction (ED). However, uncertainties remain about whether this cut-off is age-dependent and applicable in healthy individuals. We aimed to explore ED in relation to age within a large population-based cohort of young to middle-aged, healthy individuals.Me
Nanoplastics have been proven to induce toxicity in diverse organisms, yet their effect on soil microbes like bacteria and fungi remains largely unexplored. In this paper, we used micro-engineered soil models to investigate the effect of polystyrene (PS) nanospheres on Pseudomonas putida and Coprinopsis cinerea. Specifically, we explored the effects of increasing concentrations of 60 nm carboxylat
Specific causes of death, survival, and recurrence rates were assessed in a cohort of 60 patients who had undergone surgery for craniopharyngioma between 1951 and 1988. Compared to the general population, the standardized mortality ratio (SMR) was increased [5.55; 95% confidence interval (CI), 3.68-8.22], and it was higher among females (SMR, 11.4) than males (SMR, 4.79). The risk of cardio- and c
Background: In recent years, a discourse on how to systematically consider and report threats to validity started to gain momentum within the empirical software engineering community. Aims: With this study, we aim to systematically underpin the current state of threats to validity practices in software engineering research. Method: We conduct a literature review comprising 91 papers awarded with t
The use of digital technologies to deliver primary health care has increased over the past decade. While some technologies have been shown to be medically effective and efficient, the effects of digital primary care on the policy goal of equality in the use of such types of care have not been studied using large register data. The aim of this study was to analyse how digital contacts differ from o
Aim: To conduct the first revision of the World Health Organization International Classification of Functioning, Disability and Health (ICF) Core Sets for attention-deficit/hyperactivity disorder (ADHD). Method: A Delphi-like method was used, integrating evidence from stakeholder feedback and developing and piloting the ADHD ICF Core Set platform to inform revisions to the ADHD Core Sets. Results:
Antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) is a group of autoimmune diseases with inflammation affecting small blood vessels and includes granulomatosis with polyangiitis (GPA) and microscopic polyangiitis (MPA). In this study, we investigated granulocyte and monocyte subsets in a large cohort of AAV patients with emphasis on disease activity and tendency to relapse. A
Well before large-scale quantum computers will be available, traditional cryptosystems must be transitioned to post-quantum (PQ) secure schemes. The NIST PQC competition aims to standardize suitable cryptographic schemes. Candidates are evaluated not only on their formal security strengths, but are also judged based on the security with regard to resistance against side-channel attacks. Although r
This essay endeavours to define Frederick Henry's identity, how his detached persona is affected by his experience and his love for Catherine, and finally tries to answer who he has become by the end of the novel.
Kursguide - Course Syllabus • • Details of approval The syllabus was approved by the board of the Department of Service Management and Service Studies on 2017-01-25 to be valid from 2017-02-01, spring semester 2017. General Information The course may not be included in a main field of study. The course is included in the second semester of the Master of Science programme in Service Management. Lan
https://www.ses.lu.se/en/sites/ses.lu.se.en/files/smms22_english.pdf - 2026-07-11
Microsoft Word - Course analysis GEOR02 2019.docx 1 Course evaluation and analysis GEOR02 Geology Master’s Degree Project, 45 hp July 2019 This course analysis was conducted in mid-July 2019, about 13 months after we started to offer a web-based evaluation questionnaire to newly completed degree project students at the Department of Geology. A link to the questionnaire has been sent by the library
https://www.geology.lu.se/sites/geology.lu.se/files/course_analysis_geor02_2019.pdf - 2026-07-11
