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The possible importance of virus infections before the development of islet autoimmunity and then for the appearance of clinical type 1 diabetes is reviewed. There is a lack of specific data on the role of virus to induce islet autoimmunity. There is also a paucity of data to demonstrate that virus infections may contribute to an accelerated disease process resulting in clinical onset of type 1 di
This article seeks to explain what policy approaches and policy measures are best suited for promoting new regional industrial path development and what needs and possibilities there are for such policy to change and adapt to new conditions in order to remain efficient. The article departs from the notion of Smart Specialization and discusses how regional strategies that are inspired by this appro
The Late Neolithic flint daggers of Scandinavia have long fascinated contemporary flintknappers, due to the beauty of some specimens and the presumed skill required to make them. Examination of populations of daggers in museum collections reveals differences in knapping quality. Such differences are commonly ascribed to variations in skill levels on the part of their makers, and high skill is ofte
Background and purpose — Analysis of the revision-free survival of knee and hip prostheses has traditionally been performed using Kaplan–Meier analysis and Cox regression. The competing risk problem that is related to patients who die during follow-up has recently been increasingly discussed, not least with regard to the problem of choosing a suitable statistical method for the analysis. We compar
Tillgängliga forskningsresultat om samband mellan radikalisering, terrorism och psykisk ohälsa kan ännu inte användas som underlag för beslut om ändrade rutiner eller behandlingsmetoder i klinisk psykiatrisk verksamhet. De screening- och riskbedömningsverktyg som finns tillgängliga för kliniskt bruk går inte att använda inom psykiatrin utan att psykiatrins roll i det svenska samhäl-let allvarligt There is little evidence supporting the concept of mental illness as a part of, or reason behind radicalization towards violent extremism and terrorism. There is weak evidence that lone gunmen, particularly those involved in school shootings, may suffer from mental illness to a larger degree than the general population, whereas organized terrorist groups such as jihadists and right-wing extremists
The term ‘strategic use of procurement’ indicates that the procurement (also referred to as sustainable procurement) is about more than just saving money. Other important interests such as social and environmental considerations can be promoted through public procurement. Procurers can, according to newly proposed Directives on public procurement, make better use of public procurement in support o
There is uncertainty of how external factors will affect property development costs. Clarification and mapping of these external factors and how they impact the property development process is needed in order to gain insights into total development costs in the early stages of a project. The objective of the research reported in this paper is to understand the impact of external factors, for examp
Recent literature stresses the increasing importance of global innovation networks as a new mechanism to organize innovation across geographical space. This paper investigates if institutional diversity, defined at the level of the firm, influences firms’ engagement in GINs. Institutional diversity provides knowledge about the institutional context of other countries, increased capabilities to dea
A building for users with functional disorders has been built with the aim of being a low-energy residence, based on the criteria and technology applicable to passive houses. This new application of the passive house concept in a Nordic climate has shown that challenges must be met when producing buildings with a low energy demand while also fulfilling the requirements for a good indoor climate. T
Background: Radiotherapy reduces the risk of local recurrence in rectal cancer. However, the optimal radiotherapy fractionation and interval between radiotherapy and surgery is still under debate. We aimed to study recurrence in patients randomised between three different radiotherapy regimens with respect to fractionation and time to surgery. Methods: In this multicentre, randomised, non-blinded,
