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Your search for "Identification of severity related mutation hotspots in SARS-CoV-2 using a density-based clustering approach" yielded 114808 hits

“Humanities 2000” : Legitimizing Discourses of the Humanities in Public Debate and Research Policy at the Turn of the Century

This chapter analyzes the legitimizing discourse of the humanities in two different public debates in Sweden at the end of the twentieth century and at the beginning of the twenty-first century. The first debate concerned the marginalized role of the humanities and their relation to the broader public, while the second was strongly influenced by current research policies, which had a strong focus

Key Performance Index for Creating an Integrated and Sustainable Academy - A University with the Ability to Meet Future Needs and Challenges Identified in Society and Industry

Key performance indexes (KPIs) in various forms have always been used in one way or another in the production and processing of raw materials. The need for KPIs was accentuated with the advent of industrialism in the western world. The way and strategy of manufacturing industrial products has been divided into several so-called developmental transformations. Primarily after the depression of the 1

Sex-related differences in left ventricular assist device utilization and outcomes : results from the PCHF-VAD registry

Aims: Data on sex and left ventricular assist device (LVAD) utilization and outcomes have been conflicting and mostly confined to US studies incorporating older devices. This study aimed to investigate sex-related differences in LVAD utilization and outcomes in a contemporary European LVAD cohort. Methods and results: This analysis is part of the multicentre PCHF-VAD registry studying continuous-f

Bivalirudin Versus Heparin During PCI in NSTEMI : Individual Patient Data Meta-Analysis of Large Randomized Trials

BACKGROUND: The benefit:risk profile of bivalirudin versus heparin anticoagulation in patients with non-ST-segment-elevation myocardial infarction undergoing percutaneous coronary intervention (PCI) is uncertain. Study-level meta-analyses lack granularity to provide conclusive answers. We sought to compare the outcomes of bivalirudin and heparin in patients with non-ST-segment-elevation myocardial

A communication approach for oncologists : understanding patient coping and communicating about bad news, palliative care, and hospice

Oncologists frequently approach patients to discuss difficult topics, such as bad news about cancer progression and referrals to palliative care and hospice. To communicate effectively in these difficult situations, it is helpful to assess what the patient knows and wants to know about their disease in general and, specifically, their prognosis. Although some patients fully accept the diagnosis of

Reporting Bone Cytopathology-A Proposal Based on a Single Tertiary Centre Experience

OBJECTIVE: Fine-needle aspiration cytology (FNAC) from bone lesions has been proven to be a useful diagnostic tool but lacks standardisation. The aim of the study was to evaluate the diagnostic utility of FNAC as a basis to propose and test a reporting system for bone reporting cytopathology.METHODS: This retrospective study is based on patients with bone lesions, that were approached by cytology

On catalytic preorganization in oxyanion holes : highlighting the problems with the gas-phase modeling of oxyanion holes and illustrating the need for complete enzyme models

Oxyanion holes play a major role in catalyzing enzymatic reactions, yet the corresponding energetics is frequently misunderstood. The main problem may be associated with the nontrivial nature of the electrostatic preorganization effect, without following the relevant formulation. That is, although the energetics of oxyanion holes have been fully quantified in early studies (which include both the

Negative-Ion Formation upon Soft X-ray Photoexcitation of 2-Propanol

This study investigates the formation of negative ion fragments from gas-phase 2-propanol molecules after interaction with soft X-rays near the O K-edge. The experiment was performed by detecting negative and positive ions in coincidence with time-of-flight spectrometry. The analysis of two- and three-ion coincidence data revealed that nine different anions were produced: H-, C-, CH-, CH2-, O-, OH

Body mass index and breast cancer survival in relation to the introduction of mammographic screening.

AIMS: Mammographic screening reduces mortality in breast cancer. It is not known if this reduction is more pronounced in certain groups. Obesity has been associated with worse survival following breast cancer diagnosis. This study investigates BMI in relation to breast cancer mortality, and if this association is affected by invitation to mammographic screening. METHODS: In 1976, a randomised mamm

Inflectional features and clausal structure

This paper discusses the relation between verbal inflection and clausal structure, making the claim, based on evidence from Icelandic finite verb inflection, that formal verbal features, such as Number, Person, Tense and Mood, each represents (or corresponds to) a functional head in clausal structure. More generally, the paper claims that there is a one-to-one correspondance between formal feature

Testing a Swedish version of the Consumer Emergency Care Satisfaction Scale in an emergency department and 2 observation wards.

The aim was to investigate the construct validity and internal consistency of the Swedish version of the Consumer Emergency Care Satisfaction Scale. The sample comprised 157 persons from an emergency department and an observation ward. The results showed satisfactory reliability, and an explorative factor analysis revealed 3 factors: Caring, Teaching, and Clinical Competence. The Swedish version o

Histopathological findings and follow-up after prophylactic mastectomy and immediate breast reconstruction in 100 women from families with hereditary breast cancer.

AIM: To survey the histopathological abnormalities in breasts of women who have undergone risk reducing mastectomy and to evaluate the effect of this measure on future breast cancer development. PATIENTS/METHODS: Between August 1995 and October 2006 100 consecutive women with a hereditary increased risk of breast cancer underwent prophylactic mastectomy (PM) at Malmö University Hospital. Fifty of

Comparing foreign accent and ”Rosengård Swedish”: some hypotheses and initial observations.

Within the research project ‘Language and language use among young people in multilingual urban settings’ (Lindberg 2004) my role is to describe SMG pronunciation, the pronunciation of ‘Swedish on Multilingual Ground’ (e.g. Rosengård Swedish). Thanks to means placed at my disposal by the Faculty of Humanities at Lund University, I am able to broaden my research field to include also a comparison o

A novel hollow-fibre microporous membrane liquid-liquid extraction for determination of free 4-isobutylacetophenone concentration at ultra trace level in environmental aqueous samples

In this study, a method was developed for determination of the free concentration of 4-isobutylacetophenone, a toxic degradation product of ibuprofen, in river and sewage water samples from Sweden. Sample preparation and analysis were performed by a hollow-fibre microporous membrane liquid-liquid extraction (HF-MMLLE) set-up and gas chromatography-mass spectrometry (GC-MS), respectively. In this n