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Your search for "Identification of severity related mutation hotspots in SARS-CoV-2 using a density-based clustering approach" yielded 193125 hits

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A number of guidelines exist with recommendations for diagnosis and management of mitral stenosis (MS). We systematically reviewed existing guidelines for diagnosis and management of MS, highlighting their similarities and differences, in order to guide clinical decision-making. We searched national and international guidelines in MEDLINE and EMBASE (5/4/2011-5/9/2021), the Guidelines Internationa

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Two phosphite sialyl donors, each having an auxiliary 3-(S)-phenylseleno group, were prepared and evaluated. The phenylseleno group was introduced via a new mode of generating phenylselenenic acid (‘PhSeOH’). Although the sialyl donors provided fair yields (32–76%) of the desired sialosides in glycosylations of the reactive acceptor 1,2;3,4-di-O-isopropylidene-α-d-galactopyranose, no sialylated pr

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The aggregation of the amyloid β (Aβ) peptide is one of the molecular hallmarks of Alzheimer’s disease (AD). Although Aβ deposits have mostly been observed extracellularly, various studies have also reported the presence of intracellular Aβ assemblies. Because these intracellular Aβ aggregates might play a role in the onset and progression of AD, it is important to investigate their possible origi

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Background: The purpose of this study is to determine the prevalence and morbidity of neck pain with or without cervical rhizopathy, upper extremity motor deficit and/or thoracolumbar pain in elderly men. Methods: We conducted a cross-sectional questionnaire study of 3,000 community-dwelling older men with a mean age of 75.4 ± 3.2 years (range 69–81) to determine if they had experienced neck pain

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Quantifying air-borne and structure-borne sound insulation is an important design consideration for the indoor comfort in a building. Although sound insulation performance is commonly measured experimentally, numerical methods can have time-saving and economic benefits. Further, numerical methods can be incorporated within building simulations to provide an estimate of the acoustic environment. In

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Teacher shortage and turnover is a growing problem in Sweden, yet little is known about the organisational factors associated with these problems. The current study explores teachers’ experiences of organisational processes and aims to identify relevant job demands and resources linked to professional sustainability for teachers. In this study, semi-structured focus group-interviews were conducted

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The Valgarður database is a compilation of data describing the physical and geochemical properties of Icelandic rocks. The dataset comprises 1166 samples obtained from fossil and active geothermal systems as well as from relatively fresh volcanic rocks erupted in subaerial or subaqueous environments. The database includes petrophysical properties (connected and total porosity, grain density, perme

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Research into and widespread knowledge about the Assyrian Genocide, called Seyfo by Assyrians, is a recent phenomenon. Assyrians themselves have always known of the tragic events that occurred during the First World War, but it took some time before these were conceptualized as genocide and became an important element in the collective memory of the people that demanded recognition. In this articl

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The effect of 3,4,9,10-perylenetetracarboxylic dianhydride (PTCDA) adsorption on the physical properties of the two-dimensional (2D) atomic layer superconductor (ALSC) In/Si(111)-(7×3) has been studied by angle-resolved photoelectron spectroscopy, transport measurements, and scanning tunneling microscopy. Hole doping from the adsorbed molecules has been reported to increase the superconducting tra

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Increased logistics outsourcing and importance of supply chain integration (SCI) have attracted our interest in studying how logistics service providers (LSPs) are viewed as contributors to SCI and to their clients' performance. On the basis of LSPs? roles as they emerge from SCI-performance literature and from analysis of LSP-websites on how they communicate their role(s), we discuss how this dif

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Classical scholars commonly describe the ancient concept of stylistic levels with the presupposition that it merely involves literary style, how a message is expressed in a text. A study of what the rhetorical treatises say about the stylistic levels shows, however, that they affected not only composition, but also delivery and audience reactions. The delivery and reception of a text was strongly