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Your search for "Identification of severity related mutation hotspots in SARS-CoV-2 using a density-based clustering approach" yielded 193125 hits

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Objective: Previous studies have revealed positive effects on subjective alertness, performance and general sleep patterns, with exposure to light conditions adapted to time of day according to the circadian system. This study aimed to investigate the impact of a dynamic LED light intervention on sleep quality of adolescent students. Methodology: Twenty eight seventh-grade subjects were recruited

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Examensarbetet besvarar frågan om överföringar av asylsökande till Georgien som ännu inte fått sina asylskäl utförligt utredda skulle utsätta dem för en verklig risk för omänsklig eller förnedrande behandling och därmed vara oförenliga med Europakonventionens artikel 3. Asylrätten bygger på bedömningar av individuella asylskäl. I examensarbetet studeras därför problem i Georgien som är generella nThis graduate thesis examines if readmitting asylum seekers from EU member states to Georgia without first thoroughly assessing their claims would be illegal on the grounds that it would expose them to a real risk of ill-treatment contrary to Article 3 of the European Convention on Human Rights. The basis of asylum law is protection based on individual grounds. This graduate thesis therefore studi

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Food insecurity is a reality faced by millions of people worldwide. Poor access and availability to food markets, poverty, and uncertain global system futures all exacerbate this issue. In seeking to combat food insecurity for South Carolina residents and improve the viability and resilience of local food markets around Greenville County, South Carolina, this assessment determines optimal potentia

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We report the V-assisted synthesis of Na2Ti3O7 nanorods via a conventional solid state reaction technique. Energy dispersive X-ray spectroscopy (EDS) mapping showed that V-ions are not incorporated into the main structure of the nanorods but rather V behaves as a flux agent during the growth of the nanorods. The cyclic voltammetry (CV) analysis of the samples shows changes in the redox peaks as a

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We have developed a method to fabricate crossed junctions between semiconducting (s) and metallic (m) carbon nanotubes (CNTs) combining electric field directed chemical vapor deposition growth and dielectrophoretic alignment. By separating the s- and m-CNTs with a thin dielectric an ultrasmall field effect transistor (FET) was fabricated. By using the m-CNT as a gate it was possible to modulate th

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Parasites have evolved a diversity of lifestyles that exploit the biology of their hosts. Some nematodes that parasitize mammals pass via the placenta or milk from one host to another. Similar cases of vertical transmission have never been reported in avian and nonavian reptiles, suggesting that egg laying may constrain the means of parasite transmission. However, here we report the first incidenc

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In late 2019, the Intergovernmental Panel on Climate Change (IPCC) released their much-awaited Special Report on the Ocean and Cryosphere in a Changing Climate (SROCC). High mountain areas, polar regions, low-lying islands and coastal areas, and ocean and marine ecosystems, were separately dealt by experts to reveal the impacts of climate change on these regions, as well as the responses of the na

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The fresh-water cyanobacterium Microcystis is known to form blooms world-wide, and is often responsible for the production of microcystins found in lake water. Microcystins are non-ribosomal peptides with toxic effects, e.g. on vertebrates, but their function remains largely unresolved. Moreover, not all strains produce microcystins, and many different microcystin variants have been described. Her

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Stars ejected from the Galactic Center can be used to place important constraints on the Milky Way potential. We have used Hills stars to constrain models for the Galactic potential, demonstrating that meaningful constraint can be obtained if we have samples of around 50 nearby Hills stars.

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Even though insects have comparably small brains, they achieve astoundingly complex behaviors. One example is flying moths tracking minute amounts of pheromones using olfactory circuits. The tracking distance can be up to 1 km, which makes it essential that male moths respond efficiently and reliably to very few pheromone molecules. The male-specific macroglomerular complex (MGC) in the moth anten

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Individuals with severe self-harm and experiences of lengthy psychiatric admissions often have complex mental health conditions and are at risk of suicide. In this qualitative study, self-harming individuals with >180 days of psychiatric admission over 12 months shared their experiences of Brief Admission (BA), a standardized crisis-management intervention encouraging self-admission and autonomy.

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Neuroblastoma is a childhood solid tumour originating from undifferentiated neural progenitor cells of the sympathetic nervous system. Drug resistance of childhood cancer neuroblastoma is a serious clinical problem. In the present study, we aimed to identify novel drugs that can inhibit the growth and survival of chemoresistant neuroblastoma. High-throughput screening identified a small molecule,

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The Jewel of Annual Astrology is an encyclopaedic treatise on Tājika or Sanskritized Perso-Arabic astrology, dealing particularly with the casting and interpretation of anniversary horoscopes. Authored in 1649 CE by Balabhadra Daivajña, court astrologer to Shāh Shujāʿ – governor of Bengal and second son of the Mughal emperor Shāh Jahān – it casts light on the historical development of the Tājika s

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This paper presents a critical literature review of academic articles that analyze the role of formal and informal institutions in entrepreneurial ecosystems. It discusses which types of formal and informal institutions matter for the development of ecosystems, highlighting the importance of considering the specific type of legal system of the country in which they develop, i.e. its legal origin (

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The most common, severe cases of fetal and neonatal alloimmune thrombocytopenia among whites are caused by antibodies against human platelet antigen 1a (HPA-1a). The aims of this systematic review and meta-analysis are to determine the association between maternal HLA-DRB3∗01:01 and: (1) HPA-1a-alloimmunization and (2) neonatal outcome in children born of HPA-1a-immunized women. A systematic liter

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Grancalcin is a newly discovered cytosolic calcium-binding protein, belonging to the group of EF-hand proteins. Grancalcin is specifically associated with cells originating in the bone marrow. Grancalcin binds reversibly to secretory vesicles and plasma membranes in human neutrophils and might therefore play a role in the regulation of vesicle/granule exocytosis. We describe here the production of

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Purpose: To assess the performance of a 4-step algorithm for neurological prognostication after cardiac arrest recommended by the European Resuscitation Council (ERC) and the European Society of Intensive Care Medicine (ESICM). Methods: Retrospective descriptive analysis with data from the Target Temperature Management (TTM) Trial. Associations between predicted and actual neurological outcome wer

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Endwall film cooling upstream of the leading edge (LE) of a vane presents a relatively complex flow phenomenon due to the horseshoe vortices (HVs) generated at the LE region. Upstream of the LE region, the coolant flow has difficulties to eject out. This research work focuses on controlling the jet holes coolant coverage upstream of the LE region. Compound angle holes in staggered arrangement are

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In this thesis, a new theoretical framework is developed to study the relationship between human capital and economic development in a different perspective. The aim of this thesis is to examine the relationship between output composition and composition of education expenditure. Output composition is represented by the share of high value added sectors in total value added and composition of educ