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Severe hypoglycemia was induced by insulin in lightly anaesthetized (70°o N2O) and artificially ventilated rats. Brain tissue was frozen in situ after spontaneous EEG potentials had disappeared for 5. 10. 15 or 30 min and cerebral cortex concentrations of labile organic phosphates, glycolytic metabolites, ammonia and amino acids were determined. In other experiments, recovery was induced by glucos

The aim of this study was to evaluate some bioassays that are different in principle: cell counting, colony forming assay, 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl-tetrazolium bromide (MTT), sulforhodamine B (SRB), crystal violet, and alamarBlue, with respect to their ability to measure cisplatin-induced cell death of in vitro-cultivated squamous cell carcinoma of the head and neck (SCCHN). Cispl

OBJECTIVE: To determine the diagnostic value of metaiodobenzylguanidine (MIBG) scintigraphy compared with computed tomography (CT) for the localization of phaeochromocytomas in clinical practice. DESIGN: Retrospective comparison between MIBG scintigrams and CT for localization of phaeochromocytomas in all patients successively examined with MIBG scintigraphy in Malmo from 1984 until January 1997.

Soft tissue sarcomas (STS) are a heterogeneous group of highly malignant mesenchymal tumors that account for ~1% of all malignancies. Frequent heterogeneity and pleomorphism along with suboptimal diagnostic reproducibility and insufficient prognostic markers make clinical management of these tumors difficult. This thesis has applied microarray-based gene expression and copy-number profiling to STS

Objective: To investigate the association between human herpesviruses and multiple sclerosis ( MS), as well as between measles virus and MS. Methods: The authors identified prospectively collected serum samples from 73 MS cases and retrospective sera from 161 MS cases in two population-based serum bank registers. Analyses of IgG antibody responses in cases and matched referents were performed for

Conclusions. The results indicate that SOM of extreme duration, and maybe also the treatment of SOM, are risk factors for developing permanent hearing loss, both conductive and sensorineural. Objective. Fluctuating or persisting hearing loss of varying degrees is known to accompany secretory otitis media ( SOM). The aim of this study was to detect possible hearing sequelae in young adults who had

Allochthonous organic carbon in aquatic systems is metabolized by heterotrophic bacteria, with significant consequences for the biostructure and energy pathways of freshwater ecosystems. The degree to which allochthonous substrates support growth of bacteria is largely dependent on bacterial growth efficiency (BGE), i.e., bacterial production ( BP) per unit of assimilated carbon. Here we show how

Process development, optimization and robustness analysis for chromatographic separation are often entirely based on experimental work and generic knowledge. This paper describes a model-based approach that can be used to am process knowledge and assist in the robustness analysis of an ion-exchange chromatography step using a model-based approach. A kinetic dispersive model, where the steric mass

Herbivorous zooplankton may have a pronounced influence on pelagic microorganisms in Arctic freshwaters. We quantified experimentally the size-selective feeding of several zooplankton groups on pelagic microorganisms in high Arctic tundra systems. Our experiments and field study focused on dominant herbivores in Arctic freshwaters, including the cladoceran Dophnia, the copepod Diaptomus and the an

BACKGROUND: Methylation at CpG dinucleotides in genomic DNA is a fundamental epigenetic mechanism of gene expression control in vertebrates. Proteins with a methyl-CpG-binding domain (MBD) can bind to single methylated CpGs and most of them are involved in transcription control. So far, five vertebrate MBD proteins have been described as MBD family members: MBD1, MBD2, MBD3, MBD4 and MECP2. RESULT

We present here a study of the adsorption of 2-butyne (CH3-C equivalent to C-CH3) on the Si(0 01)-2 x 1 silicon surface at room temperature using synchrotron radiation photoemission spectroscopy (XPS) and X-ray absorption spectroscopy (NEXAFS). In particular, the Si2p and C1s core levels were followed by real-time photoemission (measuring while dosing). The intensity of the Si2p surface state comp

Background. For Diffuse large B-cell lymphoma (DLBCL), the International Prognostic Index is the major tool for prognostication and considers an age above 60 years as a risk factor. However, there are several indications that increasing age is associated with more biological complexity, resulting in differences in DLBCL biology depending on age. Methods. We conducted a registry-based retrospective

This chapter reassesses the modernization processes at work in Republican China during the Warlord period between 1911 and 1927 by focusing on corporate, public action by non-state interest groups and organizations. In particular, it looks at modes of corporate governing at the interface of business/economy and education: the realm of vocational education. The chapter examines a particularly illum

Popular Abstract in Swedish Bröstcancer är den vanligast förekommande cancerformen hos kvinnor. Under sin livstid kommer tio procent av den kvinnliga befolkningen att få bröstcancer men endast en minoritet kommer att avlida av den. Operation är den vanligaste behandlingen och kombineras oftast med strålbehandling. Armlymfödem samt nedsatt axelrörlighet och muskelstyrka är välkända sidoeffekter tilTen percent of the female population in Sweden will be diagnosed with breast cancer during their lifetime, but only a minority will die from the disease. Arm lymph oedema is a well-known complication following breast cancer treatment and the incidence varies between about 10% when axillary node dissection is performed and about 40% when axillary radiotherapy is added. The general aim of this thes

Popular Abstract in Swedish Spatiell struktur hos Corylus avellana (Betulaceae), hassel, med avseende på genetisk och morfometrisk variation Hassel, (Corylus avellana) är en vindpollinerad perenn buske som förekommer i mer eller mindre sammanhängande bestånd i stora delar av Europa. I denna avhandling har jag undersökt den genetiska och morfometriska variationen på olika hierarkiska nivåer hos haIn the present thesis, I investigated the spatial structure of genetic and morphometric variation in the widespread wind-pollinated shrub Corylus avellana (L.) Betulaceae, hazel, and related the variation to geographic distribution and different spatial scales. The plant material derived from natural populations in Europe, with special emphasis on the Baltic island of Öland, Sweden. Genetic and mo

Popular Abstract in Swedish Osteoporos (benskörhet) är en sjukdom med en störning i ämnesomsättningen i skelettet vilket leder till minskad mängd benvävnad och förändringar i benets mikrostruktur. Detta resulterar i en sämre hållfasthet och en ökad risk för frakturer (benbrott), vilka kan uppkomma spontant eller som en följd av ett lindrigt trauma (olycksfall). Andelen individer med osteoporos ökaOsteoporosis is a systemic, skeletal disease with the consequence of an increased risk of sustaining a fracture, one of the most common fractures being a vertebral fracture. The lifetime risk of sustaining a clinically diagnosed vertebral fracture from age 50 years onward is 8% in men and 15% in women. These fractures are followed by increased morbidity and mortality as well as an increased risk o

Anaerobic digestion is a microbially mediated process occurring in nature in the absence of oxygen and other non-carbonaceous electron acceptors. The majority of the carbon of the organic matter degraded in the process is transformed into carbon dioxide and methane. Most of the energy potential of the degraded material is conserved in the methane, thus providing a renewable energy carrier, which c

This dissertation has three cornerstones: * Haptics * Human-Computer Interaction (HCI) * Blind Users Haptics deals with controlling human movements and getting feedback through the sense of touch. A haptic interface transmits forces to a person’s hand or fingers in a way that mimics the sensation of touching real objects. Virtual haptic touch can be particularly useful for people with visual i

Popular Abstract in Swedish Med hackspettsögon: att förstå habitatval, revirkvalitet och reproduktionsbeslut utifrån individers beteende Min doktorsavhandling bygger både på teoretiska modeller och på fältstudier av mindre hackspett (Dendrocopos minor). För att slippa språkliga krumbukter eller tvetydigheter kommer jag hädanefter att kalla arten "småspett" i denna sammanfattning. Fältstudierna gjIn this thesis I present some connections between foraging behaviour and reproductive success, time budget, tree species use, and habitat selection. The thesis is based upon both theoretical and empirical work. All empirical studies concern a south Swedish population of lesser spotted woodpeckers Dendrocopos minor, studied between 1990 and 1996. The foraging behaviour of the lesser spotted woodpe