Search results

Background:Computed tomographic angiography (CTA) may require a non-contrast enhanced dataset for the diagnostic workup. By using dual-energy acquisition, it is possible to obtain a virtual non-contrast-enhanced (VNC) dataset, thereby possibly eliminating the non-contrast acquisition and reducing the radiation dose.Purpose:To compare image quality of VNC images reconstructed from arterial phase du

In the present study, we correlated the various lifestyle habits and their associated mutations in cell cycle (P21 and MDM2) and DNA damage repair (MLH1) genes to investigate their role in gastric cancer (GC). Multifactor dimensionality reduction (MDR) analysis revealed the two-factor model of oral snuff and smoked meat as the significant model for GC risk. The interaction analysis between identif

Isolation of DNA from blood and buccal swabs in adequate quantities is an integral part of forensic research and analysis. The present study was performed to determine the quality and the quantity of DNA extracted from four commonly available samples and to estimate the time duration of the ensuing PCR amplification. Here, we demonstrate that hair and urine samples can also become an alternate sou

Malignant melanoma is one of the most aggressive skin cancers with high potential of visceral dissemination. Since the information about melanoma genomics is mainly based on primary tumors and lymphatic or skin metastases, an autopsy-based visceral metastasis biobank was established. We used copy number variation arrays (N = 38 samples) to reveal organ specific alterations. Results were partly com

Background and Objective: Waste in clinical trials remains rife. We developed an economic model to predict the cost of trials based on input costs, duration, power, number of sites, recruitment eligibility and consenting rates. Methods: We parameterised the model for three proxy placebo-controlled surgical trials using data from a systematic review, a bespoke cost survey, and from the literature.

Tactile feedback plays a vital role in inducing ownership and improving motor control of prosthetic hands. However, commercially available prosthetic hands typically do not provide tactile feedback and because of that the prosthetic user must rely on visual input to adjust the grip. The classical rubber hand illusion (RHI) where a brush is stroking the rubber hand, and the user's hidden hand synch

Background: Healing failure after rotator cuff repair is a challenging problem. Acute, trauma-related tears are considered a separate entity and are often treated surgically. The aim of this study was to identify factors associated with healing failure in previously asymptomatic patients with trauma-related rotator cuff tears treated with early arthroscopic repair. Methods: This study included 62

Introduction: Fracture reduction and fixation of distal femur fractures are technically demanding. Postoperative malalignment is still commonly reported after minimally invasive plate osteosynthesis (MIPO). We evaluated the postoperative alignment after MIPO using a traction table with a dedicated femoral support. Methods: The study included 32 patients aged 65 years or older with distal femur fra

In household wastewater, a large proportion of organic micropollutants (OMPs) load is attributed to human urine. OMPs could pose a risk to human and environmental health when urine collected in source-separating sanitation systems is recycled as crop fertiliser. This study evaluated degradation of 75 OMPs in human urine treated by a UV-based advanced oxidation process. Fresh urine and water sample

We previously showed that two iron compounds that are orally ingested by humans, namely ferric EDTA and ferric citrate, can induce an oncogenic growth factor (amphiregulin) in human intestinal epithelial adenocarcinoma cell lines. Here, we further screened these iron compounds, plus four other iron chelates and six iron salts (i.e., 12 oral iron compounds in total), for their effects on biomarkers

Background: Welders are exposed to gas and particle emissions that can cause severe lung disease, such as chronic obstructive pulmonary disease (COPD), a leading cause of mortality and morbidity worldwide. It is difficult to detect COPD early and therefore mitigating measures may be delayed. The aim of this study was to investigate lung health in welders and evaluate new sensitive methods with pot

Purpose: Bone marrow is the primary site of skeletal metastases in prostate cancer. 18F-sodium fluoride (NaF) can be used to detect malignant activity, but also identifies irrelevant degenerative cortical uptake. Normal radiotracer activity in solely the marrow has yet to be described and could be a first step towards automated tumor burden calculation as SUV thresholds. We aimed to investigate no

Public transport affects people on a daily basis and therefore it is important for the public transport sector to improve the user experience for travellers. Simplicity is a keyword in the improved user experience where mobile solutions play an important role for the experience. The aim in this master thesis is to explore ways how to use a smartphone to make it easier for travellers and how to pre

Chitosan films for food packaging applications were prepared from shrimp and cricket chitosan, enriched with Schisandra chinensis extract. Physicochemical and antibacterial properties of the films were studied and compared with references studying similar chitosan films. Chitosan is a biodegradable polymer, mostly harvested from shells of crustaceans, which has been studied for packaging applicati

A recent publication introduced a new way to define all k-step linear multistep methods of order k and k+1, in a parametric form that builds in variable step-size. In this framework it is possible to continuously change method and step-size, making it possible to create better behaving adaptive numerical solvers. In this thesis general numerical solvers based on this framework have been implemente

I alla industrier där partiklar behandlas i torra prover är segregering ett stort problem. Segregering kan ske vid olika steg i processen där partiklarna i fråga till exempel transporteras, blandas eller bara lagras. Det uppskattas att uppemot 30 % av all fördröjning i processer sker på grund av segregering av partiklar(Johanson, 2014). Detta leder till kritiska konsekvenser för ett företag så somSegregation is a well-known process problem that may cost companies quality and time. The aim of this project was to establish a fundamental understanding about sifting segregation by using the sifting segregation tester described in the ASTM International standard. In this work, Cellets and Suglets were used to study particles tendency to segregate at different weight ratios and different particl

Purpose: The purpose of this study is to deepen the understanding of industrial networks in the context of Chinese indigenous innovation policies. More specifically, it is the intention to explore which relationships of Chinese ICT firms with various business and non-business actors can facilitate directly or indirectly its innovativeness. Attention is also paid to the impact of overall innovation

Background: Anterior cruciate ligament injury is a common knee injury and the treatment may be surgical and/or conservative. Different studies have shown surgical and conservative treatment, respectively, as the best intervention. Therefore it is uncertain which treatment is preferable. When searching in PubMed, no articles were found describing the thoughts and experiences of orthopedists and phy

Abstract The present thesis is concerned with the investigation of a metalorganic catalyst, a Pt complex used for C-C or C-N single bond formation in a cross coupling reaction. The investigated catalysts are used in a homogeneous reaction. In this study I have used chemical methods for the synthesis of the catalytic materials, a number of different techniques for the characterization of the catal

Vilken roll Hippocampus har i det episodiska minnessystemet är hett omdebatterat. En nylanserad teori, Competitive Trace Theory, stipulerar att strukturen ”kontextualiserar” minnen genom att skapa nya, multimodala minnesspår vid varje reaktivering av dem. Alla olika minnesspår har en gemensam, överlappande komponent samt en unik icke-överlappande komponent, och spåren konkurrerar om att slutligenThe role of the Hippocampus in episodic memory has been fervently discussed for a long time. A new model, titled ”Competitive Trace Theory”, holds that the role of this temporal lobe structure is to “contextualize” memory. This is achieved by the establishing of new, multi-modal memory traces every time the memory is reactivated. These distinct memory patterns all share a mutual component of the m