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The Gut Bacterial Flora - Focus on Early Life and Physiological Traits

Popular Abstract in Swedish Fetma, övervikt och allergi är ett problem i många delar av världen och förändringar i tarmens bakterieflora kan vara en av flera orsaker. Människan har tio gånger fler mikroorganismer än mänskliga celler. Flest mikroorganismer finns i tarmen och de brukar gemensamt kallas för tarmfloran. Många bakterier är helt oskadliga och en del är dessutom nödvändiga för att vi tilThe gastrointestinal tract of the foetus is considered sterile but during vaginal birth the neonate comes into contact with bacteria from the maternal vaginal and intestinal microbiota. The main focus of this doctoral thesis was to elucidate the initial bacterial ecosystem in newborns and to relate microbial perturbations to physiological traits. The bacterial flora was mainly studied with molecul

Shame, Blame, and Passion: : Affects of (Un) sustainable Wardrobes

In order to change consumption patterns into something that is more sustainable, it is essential that we consider the various and conflicting meanings clothes have in people's lives. This article presents an analysis of diaries written by consumers of different ages and occupations over a period of three months in 2015. These consumers documented their clothing and shoe purchases, took inventory o

Exploring human-nature relationships in academic literature on the nitrogen cycle

The nitrogen (N) cycle is a familiar concept. As is the much simplified, often diagrammatic, representation commonly used to illustrate the scale, importance and interconnectedness of this global cycle that links air, water, rocks and living beings. However, in this representation, humans are often presented as a seemingly minor entity or not explicitly shown at all. This can obscure the idea that

Expression of UDP-glucuronosyltransferase 1A4 in human placenta at term

The placenta contains a large variety of metabolizing enzymes, among them UDP-glucuronosyltransferase (UGT). Several UGT2B isozymes have so far been detected in human placenta, but little is known on placental expression of UGT1A isozymes. The antiepileptic drug lamotrigine (LTG) is a UGT1A4-substrate, and its serum concentration falls by over 50% during pregnancy, leading to impaired seizure cont

Mitral valve repair using leaflet expansion and subpartial annuloplasty in children

Objective: Mitral valve reconstruction in the pediatric population is a challenge due to the frequent combination of annular dilatation and leaflet restriction and the need for growth. We present a novel strategy using leaflet expansion and subpartial annuloplasty with polytetrafluoroethylene reinforcement. Methods: From January 2014 through May 2021, 11 children aged 5 months to 14 years (median,

"Taken from Dust, Formed from Clay" : Compound allusions & scriptural exegesis in 1QHodayota 11:20-37; 20:27-39 & Ben Sira 33:7-15

This article argues that, in 1QHa 11:20-27; 20:27-39 and Sir 33:7-15, the use of allusions to humanity's creation from dust in Genesis 2-3 and to its formation from clay in Isa 29:16; 45:9; Jer 18:4, 6 represents a conscious exegetical process in which the Genesis and prophetic traditions were read and used in light of one another. Although originating within different social environments - one se

Evaluation of threshold-based models to account for surface moisture in meso-scale aeolian sediment transport simulations

Aeolian transport rates decreases during wet conditions as the threshold shear velocity for initiation of transport increases over moist sand. This study investigates the influence of surface moisture on meso-scale aeolian transport simulations. Yearly transport rates towards the dunes are simulated with ten different threshold-based models to account for moisture effects. The ten models show larg

Dietary intakes of dioxins and polychlorobiphenyls (PCBs) and mortality : EPIC cohort study in 9 European countries

Dioxins and polychlorinated biphenyls (PCBs) are toxic, endocrine disruptors and persistent chemicals for which the main exposure source is diet due to their bioaccumulation and biomagnification in food chains. Cohort studies in the general populations have reported inconsistent associations between these chemicals in serum/plasma and mortality. Our objective was to study the association between d

Functional implications of the pH-trait distribution of the microbial community in a re-inoculation experiment across a pH gradient

We compared the influence of the microbial community composition and the environmental conditions for the functioning - microbial growth and respiration - and trait distribution - bacterial pH tolerance - of soil microorganisms across a pH gradient. Sterilised soil microcosms, including pH 4.1, 5.2, 6.7 and 8.3, with added plant litter were inoculated with unsterilized soil in a factorial design a

Adsorption of acetylene and hydrogen on Pd(111) : Formation of a well-ordered ethylidyne overlayer

The C2H2(+H)/Pd(111) system has been studied using high resolution core level spectroscopy and low energy electron diffraction (LEED). Two ordered phases were found when adsorbing C2H2 at 125 K, giving rise to a (2 × 2) and a (√3 × √3)R30° LEED pattern, respectively. When preadsorbing H at 110-150 K, the sticking probability of the C2H2 molecules is strongly reduced and only the (√3 × √3)R30° over

The structure of aggrecan fragments in human synovial fluid : Evidence for the involvement in osteoarthritis of a novel proteinase which cleaves the Glu 373-Ala 374 bond of the interglobular domain

Synovial fluid was collected from patients with recent knee injury and from patients with early or late stage osteoarthritis. Chondroitin sulfate-substituted aggrecan fragments present in these fluids, and in normal bovine synovial fluid, were purified by cesium chloride gradient centrifugation, enzymically deglycosylated and fractionated by gel filtration on Superose-12. Each sample contained two

Differential effects of insulin-like growth factor-I on matrix and DNA synthesis in various regions and types of rabbit tendons

Tendon healing and integration of tendon grafts may be site or donor specific. To determine if differences exist in sensitivity to growth factors that have the potential to influence tendon repair, we compared the effect of recombinant human insulin-like growth factor-1 on various types of tendon segments. The dose response effects on proteoglycan, collagen, noncollagen protein, and DNA synthesis

Methodology for evaluation of hazards from solid waste and landfill generated leachate

Popular Abstract in Swedish Avfall har alltid uppkommit i alla samhällen i alla tider. Det vanligaste sättet att hand om det har varit att samla avfallet i soptippar (deponier) på mark som ansetts obrukbar, t.ex. i sankmarker utanför bebyggelsen. I takt med ökad konsumtion och produktion har också mängderna avfall ökat. Anledningen till att avfall och avfallshantering kommit alltmer i fokus i miljA methodology based on an analytical protocol for evaluation of hazards from landfill leachate and solid waste is described. A dynamic analytical protocol, the LAQUA protocol, including measurements of inorganic and water-quality parameters, polar and non-polar organic marker compounds, and toxicity, was constructed. An acute toxicity test, using the brackish water crustacean Artemia salina as tes

A dining room at work. A multi-cultural arena för eating.

Countries all over Europe have faced growing migration figures since World War II. Not least immigration from countries far away from European traditions and culture will make an impact in general and also when it comes to food, meals and eating. The estimation is that more than one out of five Swedes in now living generations has roots in other countries and cultures. Segregation from aspects of

Nuclear colocalization of c-myc protein and hsp70 in cells transfected with human wild-type and mutant c-myc genes

Using immunofluorescence and electron microscopy we have studied the localization of wild-type and mutant c-myc proteins transiently expressed in CV-1 cells. In agreement with our previous observations, wild-type c-myc protein accumulated in large amorphous globules in the nucleus. All mutant proteins tested accumulated in the nucleus as well, but gave rise to morphologically different inclusion b

Context, image and the case of the Shahbag movement

This research discusses the importance of a photograph of an accused war criminal, Abdul Kader Molla, during the period immediately before the emergence of the Shahbag movement in Bangladesh. The image captures Kader Molla flashing a V sign, and it was taken in the moments after he had been sentenced to life imprisonment by the International Crimes Tribunal in Bangladesh in 2013. After Kader Molla

Mouse ten-m/Odz is a new family of dimeric type II transmembrane proteins expressed in many tissues

The Drosophila gene ten-m/odz is the only pair rule gene identified to date which is not a transcription factor. In an attempt to analyze the structure and the function of ten-m/odz in mouse, we isolated four murine ten-m cDNAs which code for proteins of 2,700-2, 800 amino acids. All four proteins (Ten-m1-4) lack signal peptides at the NH2 terminus, but contain a short hydrophobic domain character

Disruption of the L chondrite parent body: New oxygen isotope evidence from Ordovician relict chromite grains

Mid-Ordovician fossil meteorites found in the Thorsberg quarry, southern Sweden, are believed to have been deposited during a period of enhanced meteorite flux following the fragmentation of the L chondrite parent body. During diagenesis, the fossil meteorites were largely replaced by a secondary mineral assemblage. However, primary chromite grains have been preserved. High-precision oxygen isotop

Physicians' attitudes towards end-of-life decisions: a comparison between seven countries

In the context of an European collaborative research project (EURELD), a study on attitudes towards medical end-of-life decisions was conducted among physicians in Belgium, Denmark, Italy, the Netherlands, Sweden and Switzerland. Australia also joined the consortium. A written questionnaire with structured questions was sent to practising physicians from specialties frequently involved in the care

IR and EXAFS spectroscopic studies of glyphosate protonation and copper(II) complexes of glyphosate in aqueous solution

The varying degrees of protonation of N-(phosphonomethyl)glycine (PMG, glyphosate) were investigated with infrared JR) spectroscopy and ab initio frequency calculations. The zwitterionic nature of PMG in solution was confirmed, and intramolecular hydrogen bonding was identified. Successive protonation of the PMG molecule follows the order amine, phosphonate, carboxylate. Intramolecular hydrogen bo