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Metaboliter är nedbrytningsprodukter av vår kost. De första 418 TEDDY barn som fått en första autoantikropp jämfördes med kontroller utan autoantikroppar. Plasma från blodprov undersöktes och 853 olika metaboliter identifierades.Fanns det ett mönster av metaboliter som visade att autoantikroppar höll på att utvecklas?Låga nivåer av lecitin i blodet ökade risken för att få en ö-cellsautoantikropp.L
C-vitamin påverkar betacellernas funktion. Frågeställningen var om för lite eller för mycket C-vitamin i blodet påverkade risken för TEDDY barnen att få en första autoantikropp mot antingen insulin (IAA) eller GAD (GADA).Ju mer C-vitamin i blodet desto mindre var risken att ett TEDDY barn skulle få IAA, men inte GADA, som första autoantikropp.Mängden C-vitamin i blodet påverkar således risken för
Föreslagna omgivningsfaktorer för celiaki är mycket gluten och magsjuka förorsakat av virus såsom adenovirus, enterovirus, rotavirus eller reovirus. Det är oklart om gluten och virus kan påverka varandras effekter.I studien undersöktes 83 TEDDY barn som utvecklat TGA (vävnadstransglutaminasautoantikroppar), förstadiet till celiaki, och 83 TEDDY barn utan TGA men av samma kön, ålder och ärftlig ris
Sedan slutet av 1800-talet har virus misstänkts ligga bakom autoimmun (typ 1) diabetes. Hittills har igen lyckats ta reda på om virus kan förorsaka diabetes.I TEDDY studien har barnen lämnat ett blodprov var tredje månad från 3 månaders ålder fram till fyra års ålder. Under denna tid samlade föräldrarna in ett avföringsprov varje månad. Dessa prover gjorde det möjligt att ta reda på ett möjligt s
Our research
https://www.tcr.lu.se/fibrosis - 2025-10-05
Our research
https://www.tcr.lu.se/animal-models - 2025-10-05
Our division houses a network of 12 different research groups. Daniel Bexell - Molecular Pediatric OncologyYvonne Ceder - Medical Molecular BiologyChrister Larsson - Tumor Cell BiologyRamin Massoumi - Molecular Tumor PathologyAlexander Pietras - Brain Tumor BiologyKristian Pietras - Experimetal OncologyCharlotte Rolny - Immuno-Oncology GroupLars Rönnstrand - Molecular Cancer ResearchJohan Staaf -
https://www.tcr.lu.se/research-groups - 2025-10-05
Positions available at the Division of Translational Cancer Research (TCR). Welcome to apply to this collaborative research work place. NEW Postdoc Scholarship position in Ceders lab Postdoc Scholarship in Yvonne Ceders lab.A-to-I RNA editing in prostate cancer The project aims to determine if modulation of RNA editing could be the foundation for novel therapeutic strategies to reduce prostate can
https://www.tcr.lu.se/positions-available - 2025-10-05
Following a list of doctoral theses produced at the Division of Translational Cancer Research (TCR). (Click on the authers name to go directly to the full electronic version of the thesis) Ku, Anson (2020). Harnessing urinary extracellular vesicles microRNA by acoustic trapping as potential biomarkers for prostate cancer. Lund University.Niklasson, Camilla (2019). Hypoxia and Stem Cells in Normal
https://www.tcr.lu.se/doctoral-theses-list - 2025-10-05
Collected news derivative from the Division of Translational Cancer Research (TCR). Click on the links to read the full article. Automatisk koppling... Research Portal Visit our research portal via this link.
https://www.tcr.lu.se/welcome/news - 2025-10-05
Doctoral theses derived from the Division of Translational Cancer Research (TCR). Click on the title for a direct link to the full electronic copy of the thesis. Immune Response in Triple-Negative Breast Cancer - Machine Learning-based Insights from Histology and -Omics Author: Suze Julia RoosteeMain Supervisor: Johan StaafCo-supervisor: Mattias Ohlsson, Mattias AineOpponent: Raza Ali (Cambridge)D
https://www.tcr.lu.se/doctoral-theses - 2025-10-05
Our locals are situated at Medicon Village in Lund, in the south of Sweden. From Copenhagen Airport to Lund CentralIt is fairly easy getting here from Copenhagen Airport (CPH) via train and a ticket costs around 180 SEK (16 EURO). You can download the Skånetrafiken app for buying tickets easily since you can no longer by tickets on the train.Tutorial on Youtube on how to take the train to LundSkån
https://www.tcr.lu.se/welcome - 2025-10-05
Daniel Bexell Molecular Pediatric Oncology Yvonne Ceder Medical Molecular Biology Christer Larsson Tumor Cell Biology Ramin Massoumi Molecular Tumor Pathology Alexander Pietras Brain Tumor Biology Kristian Pietras Experimental Oncology Charlotte Rolny Immuno-Oncology Group Lars Rönnstrand Molecular Cancer Research Johan Staaf Breast/Lungcancer Kazi Uddin Molecular Cancer Medicine Calendar Link to
https://www.tcr.lu.se/tcr - 2025-10-05
Wild-type chick at Embryonic day E5. Wild-type chick at Embryonic day E9.
https://www.tcr.lu.se/embryo - 2025-10-05
Bexell lab For a complete list of publications, please visit our Lund University Research Portal page (linked on the right hand side).Selected publicationsKarlsson J, Yasui H, Mañas A, Andersson N, Hansson K, Aaltonen K, Jansson C, Durand G, Ravi N, Ferro M, Yang M, Chattopadhyay S, Paulsson K, Spierings D, Foijer F, Valind A, Bexell D, Gisselsson D. (2024) Early evolutionary branching across spat
https://www.tcr.lu.se/research-groups/molecular-pediatric-oncology/publications - 2025-10-05
Team members Matilda Engström MD Dora Adamic PhD student Hanna Chahin MD, PhD student Alexandra Seger PhD student Aleksandra Adamska Post-doc Erick Muciño Olmos Post-doc Joachim Tetteh Siaw Postdoc Chiara Lago Post-doc Kristina Aaltonen Associate researcher Javan Esfandyari Research engineer Caroline Jansson Lab technician Katarina Turesson Research administrator Daniel Bexell Group leader
https://www.tcr.lu.se/research-groups/molecular-pediatric-oncology/bexell-lab - 2025-10-05
The Bexell lab is grateful for the generous funding from: The European Research CouncilThe Swedish Research CouncilThe Swedish Childhood Cancer FoundationThe Swedish Cancer SocietyThe Medical Faculty at Lund UniversityALF goverment fundingThe Crafoord FoundationÅke Wiberg FoundationThe Royal Physiographic Society in LundBerth von Kantzow Foundation Research portal Visit the Molecular Pediatric Onc
https://www.tcr.lu.se/research-groups/molecular-pediatric-oncology/funding-support - 2025-10-05
We are dedicated to help children with cancer and our work is focused on neuroblastoma, a cancer derived from the sympathetic nervous system. Our overall goals are to investigate mechanisms of metastasis and treatment resistance, and to identify and test novel therapies against high-risk neuroblastoma. We have three main aims: 1. DEVELOPMENT OF CLINICALLY RELEVANT CANCER MODELSClinically relevant
https://www.tcr.lu.se/research-groups/molecular-pediatric-oncology/research - 2025-10-05
In excess of our standard lab equipment we have some specialised machines for certain tests or imaging. IVIS-CTIn Vivo Imaging System Spectrum CT 3D The IVIS Spectrum CT enables longitudinal workflows to characterize disease progression and therapeutic effect in animals throughout the complete experimental time frame with both quantitative CT and optical reconstructions. The preclinical models inc
https://www.tcr.lu.se/equipment - 2025-10-05
In Vivo Imaging System Spectrum CT 3D The IVIS Spectrum CT enables longitudinal workflows to characterize disease progression and therapeutic effect in animals throughout the complete experimental time frame with both quantitative CT and optical reconstructions. The preclinical models includes oncology, toxicology, cardiovascular disease, neurological disorders, inflammation and other related dise
https://www.tcr.lu.se/equipment/ivis-ct - 2025-10-05
