Osteoporotic fracture is among the most common and costly of diseases. While reasonably heritable, its genetic determinants have remained elusive. Forearm fractures are the most common clinically recognized osteoporotic fractures with a relatively high heritability. To establish an atlas of the genetic determinants of forearm fractures, we performed genome-wide association analyses including 100,0

This chapter points to the fact that notwithstanding the global spread of English-medium instruction (EMI) and a growing body of research into EMI in different disciplines and higher education contexts, transnational, and comparative studies on EMI that draw on large-scale cross-institutional data are extremely scarce. Hence, the TAEC Corpus was created as part of the Erasmus+ project "Transnation

Context. Multi-planet systems are important sources of information regarding the evolution of planets. However, the long-period planets in these systems often escape detection. These objects in particular may retain more of their primordial characteristics compared to close-in counterparts because of their increased distance from the host star. HD 22946 is a bright (G = 8.13 mag) late F-type star

Cross-section measurements for a Z boson produced in association with high-transverse-momentum jets (p T ≥ 100 GeV) and decaying into a charged-lepton pair (e + e − , μ + μ −) are presented. The measurements are performed using proton–proton collisions at s = 13 TeV corresponding to an integrated luminosity of 139 fb −1 collected by the ATLAS experiment at the LHC. Measurements of angular correlat

This entry describes the basic aspects of grounded theory method (GTM) and covers four key points. First, the goal of GTM is to generate a theory. Often the coding procedures are leveraged independently by researchers for data analysis, not to generate a theory. Second, the use of GTM implies a noncommittal literature review, where the emerging theory determines the relevance of that literature re

Background: Opioid-related overdose deaths remain a common cause of death in many settings, and opioid maintenance treatment is evidence-based for the treatment of opioid use disorders. However, access to such treatment varies and is limited in many settings. Methods: The present study examines the longitudinal effects of a regional patient choice reform which substantially increased availability

BACKGROUND: Three-dimensional (3D) printing of highly porous orthopaedic implants aims to promote better osseointegration, thus preventing aseptic loosening. However, short-term radiostereometric analysis (RSA) after total knee arthroplasty (TKA) has shown higher initial migration of cementless 3D-printed tibial components compared with their cemented counterparts. Therefore, critical evaluation o

Data standards for quality registries should be evidence-based and follow guideline recommendations. To optimally monitor quality of care, not only patient-level variables, but also centre-level variables need to be included. Here we describe the development of variables to audit the structure and processes in cardiac rehabilitation for patients after myocardial infarction, and the resulting data

Background The 6-min walk test (6MWT) is widely used to assess exercise capacity across chronic health conditions, but is currently not useful to assess symptoms, as the scores do not account for the 6-min walk distance (6MWD). We aimed to 1) develop normative reference equations for breathlessness and leg discomfort intensity expressed as modified Borg (mBorg)/6MWD ratios; and 2) validate the equ

Nowadays, superparamagnetic iron oxide nanoparticles (SPIONs) have a dominant role in many subfields of biomedicine. Owing to their peculiar properties, they can be employed for magnetic separation, drug delivery, diagnostics, and hyperthermia treatments. However, these magnetic nanoparticles (NPs) suffer from low unit magnetization due to size constraints (up to 20-30 nm) to exhibit superparamagn

In this study, the physicochemical, textural, and sensory properties of high-moisture meat analogues (HMMA) prepared with hempseed protein concentrate (HPC), in combination with wheat gluten (WG), and chickpea protein concentrate (CPC), were investigated. The results showed that the protein materials exhibited different behaviours during processing and cooking. Mixing HPC with WG resulted in highe

The Sun is magnetically active and often produces eruptive events on different energetic and temporal scales. Until recently, the upper limit of such events was unknown and believed to be roughly represented by direct instrumental observations. However, two types of extreme events were discovered recently: extreme solar energetic particle events on the multi-millennial time scale and super-flares

Internationalization has become one of the main strategic goals of universities as part of their endeavors to prepare students for careers in a globalized world. However, the establishment of English-medium instruction (EMI) has raised concerns about the quality of teaching and learning, given that most stakeholders involved in the process are second language (L2) speakers of English. Therefore, a

Objectives: Global health challenges are complex and new approaches are pivotal. Engagement in arts and cultural activities is commonplace across different cultures, and research shows associations with benefits for health and wellbeing. Using the arts for health promotion and prevention of illness has increased worldwide. Study design: A population-based study. Methods: Data were obtained from th

BACKGROUND: Knowing whether interventions addressing everyday life as a whole can affect work readiness for people with severe mental health issues would be important for how to develop support. OBJECTIVE: To compare two groups of people with mental health problems, receiving either of two types of 16-week activity-based interventions, Balancing Everyday Life (BEL) or Care as Usual (CAU), regardin