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Aim To present a systematic literature review (SLR) on efficacy, immunogenicity and safety of vaccination in adult patients with autoimmune inflammatory rheumatic diseases (AIIRD), aiming to provide a basis for updating the EULAR evidence-based recommendations. Methods An SLR was performed according to the standard operating procedures for EULAR-endorsed recommendations. Outcome was determined by
Objectives: This longitudinal study explores whether the working situation (no change in working hours despite care, reduction of working hours due to care or not working) moderates mental and physical health of informal caregivers of older people with Alzheimer's disease (AD) in Italy. Methods: Data from a sample of 146 caregivers of older people with moderate AD involved in the UP-TECH trial acr
In patients with muscle invasive bladder cancer (MIBC), neoadjuvant chemotherapy (NAC) prior to radical cystectomy has improved survival but there is an urgent unmet need to identify prognostic and predictive biomarkers to stratify patients who will benefit from treatment. This study aimed to examine the composition of tumor-infiltrating immune cells in MIBC, with particular reference to the clini
Introduction: For fast and effective antibiotic therapy of serious infections like sepsis, it is crucial with rapid information about antibiotic susceptibility, especially in a time when the number of infections caused by multi resistant bacteria has escalated in the world. Methods: Here, we have used a semi-quantitative MALDI-TOF-MS based method for antibiotic resistance detection, MBT-ASTRA™, wh
BACKGROUND: It is not clear if the European Systematic Coronary Risk Evaluation algorithm is useful for identifying prevalent subclinical atherosclerosis in a population of apparently healthy individuals. Our aim was to explore the association between the risk estimates from Systematic Coronary Risk Evaluation and prevalent subclinical atherosclerosis.DESIGN: The design of this study was as a cros
Purpose: The aim of this study was to compare the effects of four months of two types of structured training regimes, static standing (StS) versus dynamic standing (DyS), on passive range of motion (PROM) and spasticity in the hip among non-ambulatory children with cerebral palsy.Method: Twenty non-ambulatory children with cerebral palsy participated in an exercise intervention study with a crosso
Adaptive as well as innate immune responses contribute to the development of atherosclerosis. Studies performed in experimental animals have revealed that some of these immune responses are protective while others contribute to the progression of disease. These observations suggest that it may be possible to develop novel therapies for cardiovascular disease by selectively modulating such atheropr
The transcriptional response of hosts to genetically similar pathogens can vary substantially, with important implications for disease severity and host fitness. A low pathogen load can theoretically elicit both high and low host responses, as the outcome depends on both the effectiveness of the host at suppressing the pathogen and the ability of the pathogen to evade the immune system. Here, we i
Background. Thrombotic vascular occlusion resulting in infarction occurs during hyperacute rejection of allografts transplanted into sensitized patients and remains a major problem in experimental xenotransplantation. A similar process is also found in disorders of diverse etiology including atherosclerosis, vasculitis, and disseminated intravascular coagulation. Methods. We have previously constr
Background : Colorectal cancer (CRC) is considered one of the most common forms of cancer in the Western world. High intake of red and processed meat is considered to increase CRC development. Objective : This study examined associations between intake of red meats, poultry, and fish and incident CRC, and if weight status modifies the associations. Design : In the Malmö Diet and Cancer Study, diet
B cell lymphomas (BCLs) are a group of severe cancers, afflicting both men and women at different ages. Gene expression profiling (GEP), have during the latest decades fundamentally contributed to a better classification and biological understanding of the different BCLs. Most studies using GEP have analyzed mRNA from tumor tissue constituted of both tumor cells and non-malignant bystander cells.
Råd och anvisningar till doktoranden och institutionen i samband med disputation inom den naturvetenskapliga fakulteten Sida 1 av 13 Kansli N RÅD OCH ANVISNINGAR Datum 2024-06-05 Råd och anvisningar till doktoranden och institutionen i samband med disputation inom den naturvetenskapliga fakulteten 1 Avhandlingen Doktorsavhandlingen utformas antingen som ett enhetligt sammanhängande vetenskapligt v
Råd och anvisningar till doktoranden och institutionen i samband med disputation inom den naturvetenskapliga fakulteten Sida 1 av 13 Kansli N RÅD OCH ANVISNINGAR Datum 2025-11-13 Råd och anvisningar till doktoranden och institutionen i samband med disputation inom den naturvetenskapliga fakulteten 1 Avhandlingen Doktorsavhandlingen utformas antingen som ett enhetligt sammanhängande vetenskapligt v
https://www.naturvetenskap.lu.se/sites/naturvetenskap.lu.se/files/2025-11/Rad-och-anvisningar-disputation-251113.pdf - 2026-07-22
In recent years, the drawbacks of parallel systems in Disaster Risk Reduction (DRR) and Climate Change Adaptation (CCA) have been acknowledged in professional and academic communities, where the need for integration of the two fields in connection to development has been stressed. In this regard, the concept of resilience as an antithesis of risks has also been considered. In this study, a scoping
Despite the anticipated benefits of smart home technology (SHT) to support older adults' engagement in meaningful activities, barriers to the adoption of SHT have been identified. While research in the field of technology is surging, research on older adults playing an active role in designing and developing SHT to enhance usability is lacking. It is important to co-develop solutions to place olde
