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Neoproterozoic high-grade metamorphic rocks of the lower to middle crust are exposed along parts of the East African Orogen (EAO). However, the mechanisms and rates of exhumation of these deep orogenic rocks remain unclear. In eastern Eritrea, the rocks of the EAO comprise two lithotectonic domains: Ghedem and Bizen. The Ghedem domain consists of low-angle mylonites among lower to middle crustal g
The toxicity induced by several environmental pollutants is mediated by the aryl hydrocarbon receptor (AHR), which controls the expression of many biotransformation genes, such as cytochrome P4501A1 (CYP1A1). Previous studies have indicated that fish populations can evolve tolerance to persistent chlorinated pollutants by down-regulating the AHR pathway. Here, we measure to what extent tissue load
We compared 12-lead electrocardiograms (ECGs) derived with an improved transformation matrix from EASI leads and standard 12-lead ECGs in the detection of acute myocardial ischemia and old infarction (MI). For the ischemia test, we used ECGs of 40 patients recorded prior to and at peak inflation during percutaneous transluminal coronary angioplasty, and for old MI we used test ECGs of 382 non-MI s
Objectives. The EGFR is expressed in malignant ovarian tumor tissue, and tissue content of EGFR has been directly associated with poor prognosis in patients with ovarian cancer. The uPA system plays a role in pericellular proteolysis, cell migration, invasion, and is over-expressed in ovarian cancer. This study explored the effects of EGF on uPAR expression in the ovarian cancer cell line OVCAR-3.
Popular Abstract in Swedish Osteoporos (benskörhet) är ett tillstånd som definieras av låg benmassa och ett tillstånd som ökar med stigande ålder. Sjukdomen i sig är symptomfri men ökar risken för frakturer. Frakturer i kota, axel, handled, bäcken, och höft efter 50 års ålder är ofta förknippade med osteoporos och ca 70 000 sådana frakturer inträffar årligen i Sverige. Även artros (ledsvikt) i höfPartly due to an ageing population, the number of osteoporosis-related fractures and osteoarthritis (OA)-related hip and knee arthroplasty procedures is increasing. The individual suffering and the burden on society for these conditions is immense. Genetic contribution for the variance in bone mineral density (BMD) is estimated at around 60–80%, and for OA 50%, leaving a considerable proportion to
Beulens JWJ, van der Schouw YT, Bergmann MM, Rohrmann S, B Schulze M, Buijsse B, Grobbee DE, Arriola L, Cauchi S, Tormo M-J, Allen NE, van der A DL, Balkau B, Boeing H, Clavel-Chapelon F, de Lauzon-Guillan B, Franks P, Froguel P, Gonzales C, Halkjaer J, Huerta JM, Kaaks R, Key TJ, Khaw KT, Krogh V, Molina-Montes E, Nilsson P, Overvad K, Palli D, Panico S, Ramon Quiros J, Ronaldsson O, Romieu I, Ro
Results of three searches are presented for the production of supersymmetric particles decaying into final states with missing transverse momentum and exactly two isolated leptons, e or mu. The analysis uses a data sample collected during the first half of 2011 that corresponds to a total integrated luminosity of 1 fb(-1) of root s = 7 TeV proton-proton collisions recorded with the ATLAS detector
OBJECTIVE-Using the genome-wide association approach, we recently identified the glucokinase regulatory protein gene (GCKR, rs780094) region as a novel quantitative trait locus for plasma triglyceride concentration in Europeans. Here, we sought to study the association of GCKR variants with metabolic phenotypes, including measures of glucose homeostasis, to evaluate the GCYR locus in samples of no
Previous studies of limestone beds of mid-Ordovician age from both Sweden and China show that the Earth saw an at least two orders of magnitude increase in the influx of extraterrestrial material approximately 470 Ma, following the disruption of an L-chondrite parent body in the asteroid belt. Recovered extraterrestrial material consists of fossil meteorites and sediment-dispersed extraterrestrial
Adolescent health is regarded as central to global health goals. Investments made in adolescent health and health services protect the improvements witnessed in child health. Though Saudi Arabia has a large adolescent population, adolescent health-care only began to emerge in recent years, yet widespread uptake has been very limited. Health-care providers are key in addressing and providing the ne
Popular Abstract in Swedish Hur lurar mördarbakterier våra celler? Neutrofiler och fagocytos räddar liv Utan vårt immunförsvar så skulle vi snabbt dö i infektioner från mikroorganismer. Det består ett komplicerat system av celler och molekyler som tillsammans kan klara av att stå emot attacker från bakterier, virus, svampar eller parasiter. Cellerna i immunförsvaret utgörs av vita blodkroppar ochNeutrophils are our most numerous and deadly white blood cells and without them we would succumb quickly to infections by pathogens. The main mechanism that the neutrophils employ for our protection is phagocytosis, where they eat and enclose their target inside a membrane-bound organelle, the phagosome. Neutrophil phagosomes are highly dynamic entities, and a large amount of antimicrobial substan
Excessive antibiotics use increases the risk of resistance. Previous studies have shown that the Centor score combined with Rapid Antigen Detection Test (RADT) for Group A Streptococci can reduce unnecessary antibiotic prescribing in patients with sore throat. According to the former Swedish guidelines RADT was recommended with 2-4 Centor criteria present and antibiotics were recommended if the te
New methodologies based on supercritical fluid extraction (SFE) have been developed for the determination of fat-soluble vitamins in processed foods. The results obtained so far indicate that SFE is well suited to extraction of fat-soluble vitamins from food products, although validation work is required to establish accuracy and precision. The vitamins investigated were A, E and beta-carotene, an
Background and Purpose-To enable self-reporting of functional outcome in quality registers, the corresponding questions have to be easy to interpret. In scientific research, the modified Rankin Scale (mRS) is a standard assessment method. Such methods, with an outsider observer, are not feasible to use in quality registers. For several aspects, eg, comparisons between outcome in clinical studies a
The thermal insulation of a clothing ensemble can be measured with a thermal manikin or estimated according to ISO 9920. In ISO 9920 there are insulation tables for a number of clothing ensembles with specified garments and other tables for a variety of single garments. The insulation of single garments can be summated to estimate the insulation for a clothing ensemble. However, when a clothing en
Objective: To describe and compare the consumption of the main groups and subgroups of vegetables and fruits (V&F) in men and women from the centres participating in the European Prospective Investigation into Cancer and Nutrition (EPIC). Design: Cross-sectional analysis. Dietary intake was assessed by means of a 24-hour dietary recall using computerised interview software and standardised pro
Silver birch and common oak are known to be sensitive to standard practices in nurseries and they often show poor establishment when transplanted in urban areas. Lifting date and time in cold storage have a strong influence on stress tolerance and plant vitality. This study was carried out to assess the effect of lifting date and storage time on partial photosynthesis measured by chlorophyll fluor
Postmenopausal women in the Western world are highly burdened by osteoporotic fractures. The aim of this study is to investigate risk factors at baseline for fracture in 6416 postmenopausal women during long-term follow-up. At baseline, all women completed a questionnaire regarding background factors, diseases, current use of medications and reproductive and contraceptive history, a physical exami
