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Background: The sensitivity of newborn screening (NBS) in detecting infants that later develop symptomatic vitamin B12 deficiency is unknown. We evaluated the predictive value using NBS algorithms in detecting infants that later were clinically diagnosed with symptomatic B12 deficiency. Furthermore, we investigated whether being born in a hospital using nitrous oxide (N2O) as pain relief in labor
Starch from genetically modified potatoes was found to be highly branched compared with normal potato varieties through the use of 1H-NMR spectroscopy. The average chain length, blue-value,and the wavelength at maximum absorptivity clearly show that the new potato varieties produce amylopectin starch. Correlation between the degree of branching as determined by 1H-NMR and starch-iodine complexatio
Amyloid fibrils are associated with a number of different neurodegenerative diseases. Detailed knowledge of the fibril structure will be of importance in the search of therapy and may guide experiments to understand amyloid formation. In this paper we investigate the morphology of α-synuclein amyloid fibrils, associated with Parkinson’s disease, formed under different conditions. In particular, we
Miombo woodlands (MW) are increasingly experiencing widespread land use and land cover change (LULCC). This study explores the influence of fire, agriculture, and slope variability on LULCC in the miombo of the Beira Corridor. Land use and land cover data were derived from three Landsat images for 2001, 2008, and 2018. Slope attributes were derived from the Shuttle Radar Topography Mission (SRTM).
Sick leave due to mental health problems is increasing, and there is evidence that it is associated with the individual’s self-perceived organisational and social work environment. The aim of this study was to compare occupational therapists’ self-perceived organisational and social work environments in different job sectors. The goal is to identify the sectors with the most unfavourable work envi
Objective: The aim in this study was to assess the association between individual plasma carotenoid levels (alpha-carotene, beta-carotene, lycopene, beta-cryptoxanthin, lutein, zeaxanthin) and fruit and vegetable intakes recorded by a calibrated food questionnaire (FQ) and 24- h dietary recall records (24HDR) in nine different European countries with diverse populations and widely varying intakes
This thesis aims to reconstruct and explain variations in storm activity, humidity, vegetation composition and land cover in south-west Sweden during the past 6500 years. Two ombrotrophic bogs, Store Mosse and Undarsmosse, situated on the coastal plain of Halland, were selected for this purpose. The coastal plain of Halland is positioned in the cyclone path and is therefore particularly sensitive
Thylakoids from the green alga, Dunaliella salina, were fragmented by sonication and the appressed grasna membranes separated from stroma lamellae by partitioning in aqueous two-phase systems. The concentration and antenna size of Photosystem I in the two membrane domains were determined for cultures grown at three different light intensities. Although the antenna size of both PS is decreased with
We have previously reported suggestive linkage to chromosome 5p13-q13 in type 1 diabetic families. ISL1, a transcription factor involved in pancreas development, maps to this region. Sequencing of the ISL1 gene in patients and control subjects identified seven single nucleotide polymorphisms (SNPs) and one microsatellite in noncoding regions. Four haplotypes formed by six of these SNPs and one mic
Background: Impaction grafting in hip revision surgery is widely used but studies with mid- and long-term follow-up are scarce. Patients, methods and results A 5-year radiostereometric (RSA) follow-up of 15 hip revisions with the Exeter stem, morselized impacted allograft bone and cement revealed that 3 stems had not migrated between 2 and 5 years after revision, 11 stems had migrated to a minor
Using near-infrared femtosecond absorption spectroscopy, we have determined the S-1 energies of the carotenoids spheroidene and rhodopin glucoside in LH2 complexes of purple bacteria. The S-1 energies in the LH2 complexes yield values of 13400 +/- 100 cm(-1) for spheroidene and 12550 +/- 150 cm(-1) for rhodopin glucoside, which are very close to the S-1 energies obtained for both carotenoids in so
Ambivalence to treatment and repeated suicidal behaviour are well-known problems in suicide attempters. A randomised controlled study was performed to investigate the influence of repeated telephone contacts on treatment attendance, repetition of suicidal behaviour and mental health the year after a suicide attempt. SUBJECTS AND METHODS: One month after their suicide attempt 216 patients were rand
OBJECTIVE: In order to elucidate why spontaneously hypertensive rats (SHR) develop larger brain infarcts distal to an arterial occlusion than normotensive Wistar-Kyoto (WKY) rats, we determined the surface and volume densities of cerebral capillaries, and the regional cerebral blood flow distal to an arterial occlusion in SHR and WKY rats. DESIGN: Occlusion of the middle cerebral artery was chosen
Context: Childhood ketotic hypoglycemia ( KH) is a disease characterized by fasting hypoglycemia and increased levels of ketone bodies. The cause is unknown. Objective: The objective of the study was to study a pair of homozygotic twin boys, one of whom had severe KH from the age of 14 months, whereas the other boy was apparently healthy. Design and Results: At the age of 6 yr, the boys were thoro
Objective: The aim of this study was to assess the ability of a single 24-h dietary recall (24HDR) and food questionnaires (FQ) to predict plasma carotenoid levels at the ecological level by assessing the relationship between mean plasma carotenoid levels and mean intake of fruit and vegetables measured by 24HDR and FQ across 16 European regions. Design: A random subsample of 3089 subjects was inc
Objective: To examine the fatty acid composition of erythrocyte membranes, in relation to obesity indexes and breast cancer risk. Design: A nested case-control study. Setting: The Malmo Diet Cancer cohort, Sweden. Subjects: Among women 50 y or older at baseline (n=12803), incident breast cancer cases (n=237) were matched to controls (n=673) on age and screening date. Methods: A diet history method
