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Abstract in Norwegian Dette oplæg handler om moderniseringen af den indledende matematikundervisning ved de videregående uddannelser. Med henblik på diskussionen fremhæves tre teser og tilhørende konkrete eksempler fra et kursus som bud på, hvad ’modernisering’ omfatter og hvordan den kan realiseres. Fokus her er primært på de uddannelser, hvor den indledende matematikundervisning afholdes som sto
Popular Abstract in Swedish En magnetkamera kan med hjälp av diffusionsviktad bildtagning användas för att avbilda hjärnans nervsystem. Denna teknik kan utnyttjas för studier av hur hjärnans delar är sammankopplade, men även för att indirekt mäta egenskaper hos hjärnans mikrostruktur. Detta avhandlingsarbete vidareutvecklar de biofysikaliska modeller och mätmetoder som används för denna indirekta Diffusion MRI is widely used to study brain structure in vivo. While this technique is often applied to investigations of brain connectivity, it can also be used to infer specific information about the tissue microstructure; for example, to estimate the axon diameter. In the present work, the role of tissue microstructure and water exchange in biophysical models employed in diffusion MRI was inves
Financial theory, resource-based theory and deal flow generation are used to explain synd ication practices among venture capitalists in Belgium, France, The Netherlands, Sweden and the UK. Similar motives drive syndication in the five countries: the desire to share risk and increase portfolio diversification is more important than the desire to access additional intangible resources or deal flow.
This work focuses on measurement principles based on ultrasound for applications in industrial automation. The measurements made are of geometric nature. The methods used are when possible based on experience and/or inspiration from the study of bats. A platform for ultrasonic measurements, that allows a VME-based host computer to transmit and receive signals, with a considerable flexibility has b
We demonstrate control of the electron number down to the last electron in tunable few-electron quantum dots defined in catalytically grown InAs nanowires. Using low temperature transport spectroscopy in the Coulomb blockade regime, we propose a method to directly determine the magnitude of the spin-orbit interaction in a two-electron artificial atom with strong spin-orbit coupling. Because of a l
House dusts, collected for detection of microorganisms in buildings, sometimes have to be stored before measurement. It is possible that continued growth of microorganisms in the stored samples will increase the levels of CFU, chemical marker, biomass etc. The aim of this investigation was to assess the influence of relative humidity on microbial growth in dust samples. We have exposed dust sample
Popular Abstract in Swedish Omkring hälften av alla kvinnor kommer någon gång efter 50 års ålder att drabbas av ett benbrott. Ett benbrott ger upphov till smärta, en risk för långvarig invaliditet och förtida död. Det är viktigt att försöka hitta dem som riskerar att drabbas, eftersom det möjliggör förebyggande behandling. Hur stor risken är att man drabbas av ett benbrott på äldre dagar beror fraApproximately half of all women will sustain a fracture after the age of 50. Fractures may cause long-term disability and excess mortality. Identifying individuals at high risk of sustaining a fracture is important in the development of primary and secondary prevention strategies. In this study, initiated to identify factors associated with a high risk of future fractures, 1 044 women, all 75 yea
Context: Blood hemoglobin (Hb) declines with age in healthy elderly men, in whom decreasing testosterone has been regarded as part of normal ageing. However, the association between Hb and serum estradiol is incompletely known. Objective: To determine whether estradiol is associated with anemia/Hb and established determinants of Hb in elderly men without prostate cancer. Design, Setting and Partic
Background aims. Advanced therapy medicinal products (ATMP) are gene therapy, somatic cell therapy or tissue-engineered products regulated under (EC) No. 1394/2007 to ensure their free movement within the European Union while guaranteeing the highest level of health protection for patients. Academic good manufacturing practice (GMP) centers are major contributors in the development of ATMPs and th
Clear cell renal cell carcinoma (ccRCC) is the most common type of cancer in the adult kidney, and the prognosis of metastatic ccRCC remains poor with high mortality. In ccRCC, microRNAs (miRs) differentially expressed in tumour tissue have been identified and have been proposed to predict prognosis. The purpose of this study was to evaluate candidate miR markers identified from analysis of The Ca
Background The activity of the human enzyme thiopurine methyltransferase (TPMT) varies greatly between individuals because of genetic polymorphism. TPMT is involved in the detoxification and activation of thiopurines such as 6-mercaptopurine, 6-thioguanine, and azathioprine. These drugs are used in the treatment of acute lymphoblastic leukemia and inflammatory bowel disease. A total of 29 sequence
Aggregation of the amyloid-beta peptide (A beta) into toxic oligomers and amyloid fibrils is linked to the development of Alzheimer's disease (AD). Mutations of the BRICHOS chaperone domain are associated with amyloid disease and recent in vitro data show that BRICHOS efficiently delays A beta 42 oligomerization and fibril formation. We have generated transgenic Drosophila melanogaster flies that
BACKGROUND. Interleukin-6 (IL-6) is a multifunctional cytokine that has been implicated in the modulation of growth and progression of prostate cancer. Decreased expression of the tyrosine phosphatase SHP-1, involved in regulation of cytokine and tyrosine kinase receptor signaling, has been shown to be associated with less favorable outcome among prostate cancer patients. METHODS. Parental LNCaP c
We investigated the species richness of vascular plants at the scale of 5 3 5 km in the Swedish province of Harjedalen, and the relationship between richness and environment. Environmental variables included geographical, altitudinal, topographical, bedrock, soil type, and land-cover descriptors. The species richness was subdivided into groups of species with similar life-form, i.e. trees, dwarf s
Obstructive sleep apnoea (OSA) is associated with oxygen desaturation to a varying degree. A patent foramen ovale (PFO) may allow interatrial right-to-left shunting. The hypothesis of the current study was that oxygen desaturation will occur more often, in proportion to the frequency of respiratory disturbances, in OSA subjects with PFO than in those without. In a group of 209 subjects diagnosed w
As part of a UNICEF-sponsored Psychosocial Programme in Bosnia, data were collected from a representative sample of 339 children aged 9–14 years, their mothers, and their teachers in order to investigate risk and moderating factors in children's psychological reactions to war. Self-report data from children revealed high levels of post-traumatic stress symptoms and grief reactions, but normal leve
