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Background and aims: Pharmacotherapy can be an important part of the continuum of care for alcohol use disorder (AUD). The Swedish universal health-care system emphasizes provision of care to marginalized groups. The primary aim was to test associations of neighborhood deprivation and disadvantaged social status with receipt of AUD pharmacotherapy in this context. Design: Data from linked populati
Subarachnoid hemorrhage (SAH) is a serious clinical condition where leakage of blood into the subarachnoid space causes an acute rise in intracranial pressure and reduces cerebral blood flow, which may lead to delayed cerebral ischemia and poor outcome. In experimental SAH, we have previously shown that the outcome can be significantly improved by early inhibition of the MAPK/ERK kinase/extracellu
Purpose: There is inconsistent evidence regarding the relationship between higher intake of nuts, being an energy-dense food, and weight gain. We investigated the relationship between nut intake and changes in weight over 5 years. Methods: This study includes 373,293 men and women, 25–70 years old, recruited between 1992 and 2000 from 10 European countries in the European Prospective Investigation
There is increasing demand for sources of energy and non-meat protein with balanced amino acid profiles worldwide. Nuts are rich in protein and essential amino acids, and have a high energy value due to their high fat content. Kernels from two wild fruits in Mozambique, Adansonia digitata and Sclerocarya birrea, were selected for this study to determine their amino acid and fatty acid composition,
Based on extensive ethnographic fieldwork in Uzbekistan, this article looks at the way official state narratives are challenged by silent, unorganised, often unaware gestures of resistance at the bottom of a society. Footing on a framework suggested by Scott’s definition of infrapolitics (2012), we propose to incorporate informal practices in a definition of informality that is more inclusive and
Groundwater quality and quantity are two major challenges in arid and semi-arid regions, due to their critical roles in sustainable agricultural development. Irrigated lands are spread all over Urmia Lake's surrounding plains in Iran. Due to the risk of saltwater intrusion as a result of over-exploitation from groundwater resources, it is important to monitor the groundwater quality and quantity t
Avoiding absorption in the upper gastrointestinal tract is one of the challengesconsidering targeted colon delivery but not much attention has been paid tomicrobial activity of vector material in saliva and small intestine. The aim of thepresent study was to develop an in vitro prototype model for evaluatingdigestion of encapsulation material by oral bacterial species based on readilyobtainable sa
Here, it is shown that when two optical frequency combs with identical mode spacing but different offset frequencies copropagate through a nonlinear optical fiber, four-wave mixing between them generates new modes. Although the spacings between the new modes depend on the difference of the offset frequencies, they appear irregular because of the large number of possible four-wave-mixing processes.
Latin America is the most unequal region in the world. The current sustainable development agenda increased attention to health inequity and its determinants in the region. Our aim is to investigate the social gradient in health in Latin America and assess the effects of social capital and income inequality on it. We used cross-sectional data from the World Values Survey and the World Bank. Our sa
Two fractions from pea (Pisum sativum L.), protein isolate (PPI) and dietary fiber (PF), were newly produced by extraction-fractionation method and characterized in terms of particle size distribution and structural morphology using SEM. The newly produced PPI and PF fractions were processed into pasta-like sheets with varying protein to fiber ratios (100/0, 90/10, 80/20, 70/30 and 50/50, respecti
The protection of trade secrets in Portugal and Spain has been derived from general legal principles (of Civil Law, Penal Law and Unfair Marketing Law). This chapter on implementation of the Trade Secrets Directive (TS Directive) in Portugal and Spain presents the traditional views and positions and the implementation of the TS Directive into the respective national legal orders.In Portugal, imple
Improved water, sanitation and hygiene (WASH) are significant in preventing diarrhea morbidity and mortality caused by protozoa in low- and middle-income countries. Due to the intimate and complex relationships between the different WASH components, it is often necessary to improve not just one but all of these components to have sustainable results. The objective of this paper was to review the c
Background: The national incidence of adverse events (AEs) in Swedish orthopedic care has never been described. A new national database has made it possible to describe incidence, nature, preventability and consequences of AEs in Swedish orthopedic care. Methods: We used national data from a structured two-stage record review with a Swedish modification of the Global Trigger Tool. The sample was 4
The neglect of broader social and cultural contexts in crisis communication research raises the question of the applicability of Western originated theories in nonwestern contexts. To address the issue, this study revisits Situational Crisis Communication Theory (SCCT) in Chinese contexts by taking an online discussion on Weibo about a high-profile homicide in a McDonald’s restaurant as the case.
Generation of neurons from patient fibroblasts using a combination of developmentally defined transcription factors has great potential in disease modelling, as well as ultimately for use in regeneration and repair. However, generation of physiologically mature neurons in vitro remains problematic. Here we demonstrate the cell-cycle-dependent phosphorylation of a key reprogramming transcription fa
Monoamine neurotransmitters play an important role in the modulation of sensory, motor and autonomic functions in the spinal cord. Although traditionally it is believed that in mammalian spinal cord, monoamine neurotransmitters mainly originate from the brain, accumulating evidence indicates that especially when the spinal cord is injured, they can also be produced in the spinal cord. In this revi
Roma and Travellers (”resande”) have been present in Sweden for centuries. In the 19th and early 20th centuries, rural municipalities (kommuner) often adopted policies aimed to expel them from or to prevent them from entering the municipality. This is well established by previous research. What is less known is that another kind of territorial exclusion existed as well: that of collective violence
Objective: Hyperglycaemia during pregnancy increases the risk of adverse health outcomes in mother and child, but the genetic aetiology is scarcely studied. Our aims were to (1) assess the overlapping genetic aetiology between the pregnant and non-pregnant population and (2) assess the importance of genome-wide polygenic contributions to glucose traits during pregnancy, by exploring whether geneti
