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Peripheral nerve tumours are uncommon. Our aims were to calculate the incidence and relative frequencies, to define sites of nerve tumours and to judge preoperative symptoms and outcomes of intervention. The results of 53 patients, with 68 tumours and histopathological diagnoses of true neoplasms, who had been operated on at the Department of Hand Surgery, Malmo, Sweden, between 1986 and 2007, wer
Aliasing gives a lower bound for the sampling rate in ordinary spectral analysis of a time series. In parametric it appears at first sight that no such limitations are present. In this note we will obtain insight into this paradox by analyzing a simple Gauss-Markov process. We assume that a time series analysis is performed based on N samples of the series at equal spacing h. The result shows that
Determination of heart status during dialysis can im- prove patient monitoring. Pressure sensors in the dialysis machine measures the heart pulses that propagates in the body and enter the extracorporeal blood circuit. A peri- staltic blood pump, located in the same circuit, introduces strong periodic pressure pulses that interfere with the much weaker cardiac component. These signal characteristi
The institutional landscape of the EU has been transformed through the establishment of agencies and changes brought by the Lisbon Treaty. This article seeks to contribute to our conceptual and empirical understanding of European agencies post-Lisbon. It maps the current European agencies according to timing of establishment, size, functions, governance structures and financial arrangements, and d
To determine the importance of the phosphorylation capacity of receptor kinase as well as the ability to serve as docking sites for SH2-domain-containing signal transduction molecules, we established pig aortic endothelial cell lines stably expressing kinase-active platelet-derived growth factor (PDGF) alpha-receptors together with kinase-inactive beta-receptors, and vice versa. After stimulation
In December 2005, the WTO responded to the HIV/AIDS pharmaceutical crisis in the least developed world by voting to make the first permanent amendment to the WTO Agreements since their original negotiation during the Uruguay Round. New Article 31bis will amend the TRIPS Agreement to permit compulsory manufacturing licenses in order to facilitate supply of needed pharmaceuticals to those countries
Androgen receptor (AR) is expressed in all stages of prostate cancer progression, including in castration-resistant tumors. Eliminating AR function continues to represent a focus of therapeutic investigation, but AR regulatory mechanisms remain poorly understood. To systematically characterize mechanisms involving microRNAs (miRNAs), we conducted a gain-of function screen of 1129 miRNA molecules i
Marie Belloc Lowndes was a prolific author, publishing over forty novels in addition to plays, memoirs and a large number of short stories spanning the first five decades of the twentieth century. Most of these are now largely forgotten. Despite her obvious popularity, evidenced by a significant number of film adaptations of her novels, Lowndes has not yet reached the radar of literary studies. Th
Clofarabine has been shown to effectively induce remission in children with refractory leukemia. We conducted a prospective trial (clinicval.trials.gov NCT01025778) to explore the use of clofarabine-based chemotherapy as a bridge-to-transplant approach. Children with refractory acute leukemia were enrolled to receive two induction courses of clofarabine, etoposide, and cyclophosphamide (CloEC). Re
In the Protestant tradition the trade and commerce that surrounded different aspects of Catholic spirituality was regarded as something relatively alien. In Protestant Sweden the critique towards these aspects of Catholicism became an essential component in the anti-Catholic rhetoric that was recurring during the latter nineteenth and the early twentieth century. From the perspective of Lutheran t
The relationship between syntactic structure and prosodic structure has received increased theoretical attention in recent years. Richards (2010) proposes that Japanese allows wh-elements to stay in-situ because of a certain aspect of its prosodic system. Specifically, in contrast to some other languages like English, Japanese can prosodically group wh-elements together with their licensers. This
Although folded proteins are commonly depicted as simplistic combinations of β-strands and α-helices, the actual properties and functions of these secondary-structure elements in their native contexts are just partly understood. The principal reason is that the behavior of individual β- and α-elements is obscured by the global folding cooperativity. In this study, we have circumvented this problem
The issuing of Opinion 2/13 on the European Union’s (EU’s) accession to the European Convention on Human Rights by the Court of Justice of the EU (CJEU), followed by Case C- 284/16 Achmea and Opinion 1/17 on the compatibility with EU law of the Comprehensive Economic and Trade Agreement between Canada and the European Union (CETA), brought the concept of the autonomy of the EU legal order to the p
Introduction: Fetal growth restriction is associated with adverse perinatal outcome and the clinical management of these pregnancies is a challenge. The aim of this study was to investigate the potential of cerebroplacental ratio (CPR) to predict adverse perinatal outcome in high-risk pregnancies in the third trimester. Another aim was to study whether the CPR has better predictive value than its
Glas- och bärnstenspärlor var en del av dräkten som signalerade bärarens sociala och ekonomiska status. I artikeln presenteras pärluppsättningarna från 25 gravar daterade till yngre romersk järnålder period C1 och C2 funna i dagens Skåne. Pärlorna har ett varierat och unikt uttryck vilket stärker hypotesen att de mindre rika gravarna i Skåne, jämfört med på Själland, beror på ett mer stabilt samhäGlass and amber beads are colourful artefacts that have been much less discussed than other accessories such as fibulae. Like these, the beads were part of the dress that signalled the wearers’ social and economic status. In the article, beads from 25 graves from modern-day Scania, dated to the Roman Iron Age periods C1 and C2, are presented. In many ways they show a varied and unique expression,
