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The self avoiding walk (SAW) model of the polymer has been extended to study the equilibrium properties of double stranded DNA (dsDNA) where two strands of the dsDNA are modeled by two mutually attracting self-avoiding walks (MASAWs) in the presence of an attractive surface. We study simultaneous adsorption and force induced melting transitions and explore different phases of DNA. It is observed t
BACKGROUND: Perinatal stroke refers to a diverse but specific group of cerebrovascular diseases that occur between 20 weeks of fetal life and 28 days of postnatal life. Acute treatment options for perinatal stroke are limited supportive care, such as controlling hypoglycemia and seizures. Stem cell-based therapies offer a potential therapeutic approach to repair, restore, or regenerate injured bra
The cooperative emission of interacting nanocrystals is an exciting topic fueled by recent reports of superfluorescence and superradiance in assemblies of perovskite nanocubes. Several studies estimated that coherent coupling is localized to a small fraction of nanocrystals (10−7-10−3) within the assembly, raising questions about the origins of localization and ways to overcome it. In this work, w
The Care of Late-Stage Parkinsonism (CLaSP) study is a longitudinal, multicentre, prospective cohort study to assess the needs and provision of care for people with late-stage Parkinson’s disease and their caregivers in six European countries. As a cross-sectional study within the CLaSP study, 509 people with Parkinson’s disease completed the “Schedule-for-Meaning-in-Life-Evaluation” (SMiLE) quest
Pollution by chemicals and waste impacts human and ecosystem health on regional, national, and global scales, resulting, together with climate change and biodiversity loss, in a triple planetary crisis. Consequently, in 2022, countries agreed to establish an intergovernmental science-policy panel (SPP) on chemicals, waste, and pollution prevention, complementary to the existing intergovernmental s
Diabetic encephalopathy is a recognized complication of untreated diabetes resulting in a progressive cognitive impairment accompanied by modification of hippocampal function. The purinergic system is a promising novel target to control diabetic encephalopathy since it might simultaneously control hippocampal synaptic plasticity and glucose handling. We now tested whether streptozotocin-induced di
Scholarship addressing Shia Muslim minorities in Western contexts often refers to them as a ‘minority within a minority’ or ‘the other within the other,’ highlighting their dual-marginalization within non-Muslim societies. This paper challenges the concept of double-marginalization by examining the dynamics of transnational Shia communal spaces in north-west London and the creation of Shia spaces
Background: Technological evolution leads to the constant enhancement of monitoring systems and recording symptoms of diverse disorders. Summary: For Parkinson's disease, wearable devices empowered with machine learning analysis are the main modules for objective measurements. Software and hardware improvements have led to the development of reliable systems that can detect symptoms accurately and
Locust bean gum (LBG) is an industrially important polysaccharide used widely in food, cosmetics, textiles, and biopharmaceutical applications, where understanding its solution behaviour is important for formulation design. To address this, we investigate the structure and dynamics of LBG in aqueous solution using steady state shear rheology, static light scattering (SLS), ultra-small-angle light
Antagonistic coevolution (i.e., reciprocal adaptation and counter-adaptation) between hosts and pathogens has long been considered an important driver of genetic variation. However, direct evidence for this is still scarce, especially in vertebrates. The wealth of data on genetics of susceptibility to infectious disease in humans provides an important resource for understanding host-pathogen coevo
Very high spin states (I=50-60ℏ) have been observed in the transitional nuclei 161Er and 162Er using the Euroball γ-ray spectrometer. In 161Er, three bands are observed well above spin 50ℏ. In the positive parity, positive signature (+, + 1/2) band a discontinuity in the regular rotational behavior occurs at 109/2+ and a splitting into two branches occurs at 97/2- in the negative parity, positive
Purpose and aim: The overall aim of this study was to examine the relationship between adaptive function and cognitive factors in young adults diagnosed with autism spectrum disorder (ASD) in adult age.Methods: The study included 30 adults (age 18-30) diagnosed with ASD in adulthood. All participants were clinically referred to an adult psychiatric clinic for assessment. Adaptive functioning was m
Here, we present new models to fit small angle X-ray scattering (SAXS) data for the characterization of ion tracks in polymers. Ion tracks in polyethylene terephthalate (PET), polycarbonate (PC), polyimide (PI) and polymethyl methacrylate (PMMA) were created by swift heavy ion irradiation using 197Au and 238U with energies between 185 MeV and 2.0 GeV. Transmission SAXS measurements were performe
Australia is already experiencing climate change losses and damages. Australian governments and other institutional actors acknowledge vulnerability, yet they centre building resilience to climate change. Resilience is frequently used as a synonym for vulnerability reduction, but important ideological differences exist. Indeed, scholars have suggested that resilience, as a politico-ideological too
While the conventional forest plot is useful to present results within subgroups of patients in clinical studies, it has been criticized for several reasons. First, small subgroups are visually overemphasized by long confidence interval lines, which is misleading. Second, the point estimates of large subgroups are difficult to discern because of the large box representing the precision of the esti
Churches are in crisis. The turn to praxis in ecclesiology appears to attend to the current crisis; yet, the appearance might be deceptive. Since post-liberal ecclesiologies – such as John Milbank’s – consider neither quantitative-empirical nor qualitative-empirical accounts of concrete churches, the turn might be assessed as a turn to talk about praxis instead of a turn to praxis. Confronting Mil
